Abstract Introduction: MMP3 plays a crucial role in the process of bone erosion in the pathomechanism of rheumatoid arthritis (RA). It acts by removing the outer osteoid layer, which allows the osteoclasts to tightly connect and carry out the subsequent damage to the underlying bone. MMP3 can trigger the production of other MMPs like MMP-1, MMP-7, and MMP-9, it plays a pivotal role in the remodeling of connective tissues. Aim of the study: to assess the influence of MMP-3 serum levels and single-nucleotide polymorphisms of rs679620 in the rheumatoid arthritis patients' group in comparison to the control group. Subjects: eighty eight samples, 45 rheumatoid arthritis patients after being referred by their treating physician for regular RA

Leishmaniasis is one of the important parasitic diseases, affecting mainly low social class people indeveloping countries, and is more prevalent and endemic in the tropical and subtropical regions of old worldand new world. Despite ofbroad distribution in Iraq,little known about the geneticcharacteristics of thecausative agents. So this study was aimed to evaluate the genetic varietyoftwo IraqiLeishmaniatropicaisolatesbased on heat shock protein gene sequence 70 (HSP70) in comparison with universal isolates recordedsequences data. After amplification and sequencing of HSP70 gene,the obtainedresults were alignment alongwith homologous Leishmania sequences retrieved from NCBI by using BLAST. The analysis results showedpresence of particular g

The study uses the photometric method, which depends on the intensity of color scale levels in the image pixels. The work is based on converting color into a wavelength in each pixel; in the beginning, the work has been verified by measuring the monochromatic wavelengths of rays, such as lasers. The Matlab program (image processing) calculated the number of lasers as 325 nm, 473 nm, 477 nm, 535 nm, 603, and 785 nm, where the results were very good and had a low error rate. The elements had distinctive colors, which indicated wavelengths in the visible range. The work was done for the sulfur element found in specific Iraqi locations, such as Al-Mashraq field in Mosul province. The image processing techniques by Matlab software, with the a

A crucial area of research in nanotechnology is the formation of environmentally benign nanoparticles. Both unicellular and multicellular play an important role in synthesis nanoparticles through the production of inorganic materials either intracellularly or extracellularly. The agents (pigments, siderophores, cell extracted metabolites and reducing compounds) were used to prepare silver nanparticles with different sizes and shapes. The color variations (dark yellow, slightly dark yellow and golden yellow) arising from changes in the composition, size, and shape of nanoparticles, surrounding medium can be monitored using UV-visible spectrophotometer. These effects are due to the phenomena called surface plasmon resonance. The silver nanopa

This paper proposes two hybrid feature subset selection approaches based on the combination (union or intersection) of both supervised and unsupervised filter approaches before using a wrapper, aiming to obtain low-dimensional features with high accuracy and interpretability and low time consumption. Experiments with the proposed hybrid approaches have been conducted on seven high-dimensional feature datasets. The classifiers adopted are support vector machine (SVM), linear discriminant analysis (LDA), and K-nearest neighbour (KNN). Experimental results have demonstrated the advantages and usefulness of the proposed methods in feature subset selection in high-dimensional space in terms of the number of selected features and time spe

Background: The microbial production of substances that have the potency to suppress the growth of other microorganisms is probably one of the prevalent defense strategy developed in nature, microorganisms produce a variable bunch of microbial defense systems, which include antibiotics, metabolic by-products, lytic agents, bacteriocins and others. Objective: The purpose of the present study was to isolate and identify Enterococcus faecium isolates then detecting its ability of carrying the gene responsible for enterocin production in this species. Materials and methods: Out of 50 samples from different sources (food and clinical sources) were collected for the Enterococcus faecium isolation, and the isolated bacteria Enterococ

Cefixime is an antibiotic useful for treating a variety ofmicroorganism infections. In the present work, tworapid, specific, inexpensive and nontoxic methods wereproposed for cefixime determination. Area under curvespectrophotometric and HPLC methods were depictedfor the micro quantification of Cefixime in highly pureand local market formulation. The area under curve(first technique) used in calculation of the cefiximepeak using a UV-visible spectrophotometer.The HPLC (2nd technique) was depended on thepurification of Cefixime by a C18 separating column250mm (length of column) × 4.6 mm (diameter)andusing methanol 50% (organic modifier) and deionizedwater 50% as a mobile phase. The isocratic flow withrate of 1 mL/min was applied, the temper

Dora petroleum refinery waste water is the one of the important source of pollution by priority pollutant aromatic compound discharged to Tigris river in Iraq. the station has waste water treatment unit contains many treatment subunits The most important sub units is :skimmer units ,physiochemical unit ,daf unit, biological unit. The aim of research project is to study the ability of unit to remove the priority pollutant aromatic compound and follow up these compounds in river to study ability of river to self removal. A solid phase extraction (SPE) followed by high performance liquid chromatography-ultra violet (HPLC-UV) technique is depicted for the quantitative estimation of benzidines and phenols. Experimental studies were performed to

Wireless Body Area Sensor Network (WBASN) is gaining significant attention due to its applications in smart health offering cost-effective, efficient, ubiquitous, and unobtrusive telemedicine. WBASNs face challenges including interference, Quality of Service, transmit power, and resource constraints. Recognizing these challenges, this paper presents an energy and Quality of Service-aware routing algorithm. The proposed algorithm is based on each node's Collaboratively Evaluated Value (CEV) to select the most suitable cluster head (CH). The Collaborative Value (CV) is derived from three factors, the node's residual energy, the distance vector between nodes and personal device, and the sensor's density in each CH. The CEV algorithm operates i

Contracaecum rudolphii Hartwich, 1964 is a nematode which causes major concerns to human and wildlife animal’s health. However, the population genetics of C. rudolphii has been poorly studied in Iraq. In order to gain a deeper understanding in the outline of the genetic diversity of the nematode C. rudolphii that were isolated from its host cormorant Phalacrocorax carbo (Linnaeus, 1758), in the middle areas of Iraq, twenty specimens of C. rudolphii adults were isolated from nine individuals of P. carbo. The first (ITS-1) internal transcribed spacers (ITS) of ribosomal DNA (rDNA) of C. rudolphii were amplified using conventional polymerase chain reaction (PCR); then, the amplicons were subjected to sequencing. Concatenation of ITS

Cryptosporidiosis is a parasitic disease result from parasite Cryptosporidium parvum, that effect intestinal tract of mammals. It was recorded that this parasite causes 6% of diarrhea in immunocompetent persons and 24% in AIDS persons. The primary symptoms of this disease are non- bloody and watery diarrhea, also may cause abdominal pain, nausea, vomiting, and anorexia, .Infection can affect other organs such as gall bladder, liver, and lungs. The aims of this review article to provide the important update information of Cryptosporidium parasite, which is the causative agent of cryptosporidiosis. In conclusion cryptosporidiosis is considered a serious health problem, infect human intestinal tract of different ages, and children are

The complexity of multimedia contents is significantly increasing in the current world. This leads to an exigent demand for developing highly effective systems to satisfy human needs. Until today, handwritten signature considered an important means that is used in banks and businesses to evidence identity, so there are many works tried to develop a method for recognition purpose. This paper introduced an efficient technique for offline signature recognition depending on extracting the local feature by utilizing the haar wavelet subbands and energy. Three different sets of features are utilized by partitioning the signature image into non overlapping blocks where different block sizes are used. CEDAR signature database is used as a dataset f

This study aimed to demonstrate the biosynthesis procedure of zinc oxide nanoparticles (Zn-O NPs) by using extracellular components from environmental isolates of Escherichia coli as reducing and stabilizing agent by adding 1 g of zinc sulfate to 10 ml of bacterial extract to prepare of zinc oxide nanoparticles. These organic pollutants are considered one of the most important causes of poisoning that have great health risks to humans and are also considered one of the most dangerous environmental pollutants as they are toxic and harmful to the environment. The optimum condition for Zn-O biosynthesis was characterized through several devices and techniques such as ultraviolet- visible (UV-Vis) Atomic force microscope (AFM) X-Ray diffract

Chronic kidney disease (CKD) is a serious threat to global medicine as more than two million get CKD yearly. However, the understanding of DNA damage, DNA methylation in chronic kidney disease (CKD) remains elusive. The study goal was to establish whether homocysteine (Hcy), oxidative DNA damage (ODD), glutathione peroxidase (GPX3) and 5-methylcytosine (5mC) could be used as a potential marker of CKD. Measurements of Hcy, ODD, and GPX3 levels were done by commercial enzyme linked immunosorbent assay (ELISA) kits of 60 patients with chronic kidney disease (age range 20-87 years) and 30 age-matched healthy controls. DNA extracted from blood of patients was used to evaluate the global 5-methylcytosine (5mC) levels by the MethylFlash

Academic chemical laboratories (ACL) are considered public places  the employees come in contact with a variety of pollutants. The aim of the current study was to detect heavy metals levels in the indoor air of ACL in two universities in Baghdad city and assess their levels in the academic employees’ scalp hair as biomarkers. Air samples inside ACL were collected to detect Fe, Cd, Zn, Pb and Cu. Scalp hair samples were collected from 40 adult chemical laboratory employees aged 30-60 years, who worked 5 days/week for 6 hours a day. Personal information relating to employees such as age, duration of exposure, smoking habit and sex, was collected as a questionnaire. The results of this study concluded that academic laboratory employees w

 Klebsiella pneumoniae has become one of the most common etiologic agents in the context of recurrent UTI. Capsule is the earliest recognized factor determining bacterial pathogenicity. This study aimed to test the effects of staphyloxanthin, meropenem and a combination of them on capsule genes of Klebsiella pneumoniae. Eighty-eight gram negative bacterial isolates were collected from 150 urine specimens between September and November of 2022.after cultivation on MacConkey agar medium. Oxidase (negative) and catalase (positive) tests were performed. In addition, all isolates were found to be non-motile when their motility was further examined. The results presented that 77 (51.3%) could ferment lactose (lactose ferment

The applications of herbal medicine have recently acquired growing interest in range of the prophylaxis and treatment of diseases. Olibanum has been used since ancient eras and several reports studied the pharmacological characteristics of boswellic acid, particularly their effect on the inflammatory response, analgesic properties, and anti-arthritic activity mostly in cell lines, but new approaches include animal models to assess these natural derivatives effects taking into consideration of being safer than synthetic preparations.  The impact of olibanum oil on several parameters was studied in rats during this study. These included white blood cell (WBC) count, lactate dehydrogenase (LDH), and C reactive protein (CRP), as well as oth

High antibiotic resistance among Pseudomonas aeruginosa could be viewed as the primary cause of nosocomial infections. In this study, 60 isolates of Pseudomonas aeruginosa were isolated from urine, sputum, burn, ear and wounds swab. The major goal was to determine the relationship between MexX and MexY and the resistance of MDR P. aeruginosa to many drugs. Prevalence of multidrug resistant (MDR) Pseudomonas aeruginosa was 22 isolates (36.66%) and 38 isolates (63.34%) were found to be non-MDR isolates. Moreover, molecular detection of MexX and MexY genes was done for MDR isolates.MexY gene was found in all MDR isolates and MexX gene was detected in 2