Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
The science of The facts basically depends on the intentions of the speaker and what he deliberately waves to the interlocutor, taking into account the context in which the verbal act was received .
ان في هذه الاية الكريمة لآبلغ وصف للاكتئاب حيث الضيق الشديد والشعور باليأس من الدنيا والوحدة .
وقال المتنبي :.
كفى بك داء ان ترى الموت شافياً
وحسب المنايا ان يكن امانيا
وقال مجنون ليلى :.
وامطر في التراب سحاب جفني
وقلبي في هموم واكتئاب
الحزن والقلق والهم والغم جزء من حياة الناس وهناك كثير من العوامل الممه
... Show MoreAfter this stage in the Bible is problematic and the profane in the poetry of the AL-Sayeghs,
and found that the poems path heading towards obey religious authority because of their wills
and powers, and the insurgency in other areas, as it did not employ shady methods and puns
and intriguing, and I find the reason for this is due to the fear poet focused toward the
influence of political Sergeant, more than effusion direction ascendancy religious sergeant,
was a AL-Sayeghs stop at this border; but went to the formulations problematic diversity in
the cognitive system, he tries it all to critique, as submitted by the history of the conflicts
produced generations of oppression and conflict and tension (what my fault I
Pride in the poetic Genius in Al-Shareef Al-Murtada's poetry.Pride in the poetic genius is a rich and recurring subject .The poets always compete with each other to show their skills in composing poetry.This subject illustrates the poet's creative talents and his ability to comprehend the vocabulary of the Arabic language.Pride in the poetic gift witnessed great development which was caused by the cultural progress of the Abyssian Age. Such influences are often reflected in poetry because it is an essential part of life.
Введение
Международные контакты обусловили интерес к изучению основной формы общения – диалога. Форма диалога в каждом из контактирующих в процессе общения языков должна быть рассмотрена в разных аспектах – не только лингвистическом, но и социолингвистическом и этическом. Это объясняется тем, что в речевой коммуникации необходима как адекватность выражения мысли, так и соблюдение тради
... Show Moreالقنوات الخلفية في السياسة الخارجية الامريكية
يهدف البحث الى قياس مستوى الثقافة الاسلامية لدى الطالب الجامعي العراقي والكشف عن الفروق في المستوى الثقافي الاسلامي بين الذكور والاناث وتحدد البحث بعينة ممثلة 200طالب وطالبة من طالب الجامعات العراقية ( بغداد ، المستنصرية ) للعام الدراسي (2018-2017) ، واعتمد على المنهج الوصفي (اسلوب المسح ) لدراسة الموضوع ، وخرج البحث بعدة استنتاجات منها يعاني طالب الجامعات العراقية ( ذكور واناث ) من ضعف في مستوى الثقافة الاسلامية لد
... Show Moreشيد الفكر العربي المعاصر تحولات عدة فرضتها بعض التيارات الفكرية والفلسفية الغربية، وأثرت في تكوينه وتحديد اتجاهاته، فضلا عن التحديات التي بات لزاما عليه ان يتعامل معها ويمكن رد هذه التحديات الى عدة عوامل داخلية وخارجية أنتجت عدة تيارات تناولت موضوع العقلانية في الفكر العربي المعاصر، لعل أبرزها التيار الاصلاحي، التيار الليبرالي، والتيار العقلي النقدي
The bourgeoisie groups derived great advantages from the system upon which the Fatimids built up their Regime out the land-tax and other taxes against a fixed sum . The surpulus revenue was the prophet of the farmers . A striking feature of the Fatimid was freedom of enterprise .All sectors of economic life were free-crafts , industry and trade . The government interfered in the trade in victuals only so far to in order to guarantee the supply of wheat to the big towns
The Egyptian Bourgeoisie enjoyed also the great prosperity which was produced among other reasons by the inflationary system of Fatimid economy .
The maintenance of gold dinar being almost pure and of full weight was only possible because Egypt steadily received cons