Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
The research came to a statement in explaining the impact of movement in general in the Arabic language, as a word and sentence, in the Holy Qur’an in particular, and the Arabic syntactic movement in understanding the Qur’anic text.
The research contained two sections. Each section has two demands, an introduction, and a preface. The most prominent titles of the research are the aspect of parsing, which is one of the characteristics of the Ḍād; the definition of parsing in language and terminology; the impact of movement on understanding the Arabic text in general; and in understanding the Qur’anic text in particular
تعد الاسرة إحدى الوحدات الاجتماعية التي تهيئ الجيل المتطلع للحياة وهم الاطفال، وهي المهد الطبيعي للطبقة البشرية التي تباشر وتواجه اثراً هاماً تكوين الشخصية والسلوك الاجتماعي والخلقي ، وهي نقطة الوصول والتفاعل بين البيولوجي والاجتماعي وعنها ينشأ التفاعل النفساني ، وشبكة العلاقات الاسرية والعلاقات الخارجية المجتمعة . ومن خلال معاييرها وقيمها ينشأ السلوك سوياً كان ام مرضياً ( جانحاً ) ، ومشكلة جنوح الا
... Show Moreالدور السياسي للاحزاب الاسلامية في تركيا
Black slaves formed a section of the Murabit community, and they had an important role in wars and in settling battles to the Murabit state. Murabit state lords have depended on them in many scales such as, wars or within the community boarders
In this research, trying to highlight the reasons for the illusion, and do not want to repeat what the previous scholars and researchers from the ancients and modernists said, but to continue from where they ended, as the blogging has undergone several images that influenced the nature of the narrations, and their proximity to the truth according to the whims of the authority, or the narrator's whims and inclinations and any destination. Here we don't mean bees and plagiarism... It goes beyond the fact that traffic is made to the whims of those who write or write to it, or in it a little bit of truth and then be framed, to add exaggeration and exaggeration to it.
Sıfat - Fiillere Osmanlıcada fer’i fiil adı verilmektedir. Sıfat - fiiller için çeşitli kaynaklarda, kılın adı (kılın sanı[1]), ortaç[2], sıfat - fiil (sıfat - eylem[3]), partisip[4], isim - fiil[5] gibi terimler kullanılmıştır.
Sıfat - fiiller, isim- fiiler gibi fiilden türerler. Aldıkları belli başlı ekler vardır. Bu eklere sıfat - fiil ekleri denir.sıfat - fiiller, cümlede bir sıfat gibi görev yaparlar. Sıfatlar gibi isimlerin önün gelirler ve onları nitelerler tıpkı bir sıfat gibi ismin hal eklerini alab
... Show Moreاشكالية المواطنة في الخطاب الاسلامي المعاصر
Islamic banking refers to a system of banking or banking activity that is consistent with the principles of the Shari'ah (Islamic rulings) and its practical application through the development of Islamic economics. The principles which emphasise moral and ethical values in all dealings have wide universal appeal. Shari'ah prohibits the payment or acceptance of interest charges (riba) for the lending and accepting of money, as well as carrying out trade and other activities that provide goods or services considered contrary to its principles. While these principles were used as the basis for a flourishing economy in earlier times, it is only in the late 20th century that a number of Islamic banks were formed to provide an alternative basi
... Show Moreم,د. فرات سمير فرج
تدريسي في مديرية تربية محافظة الانبار
The study of manuscripts that related to medicine and pharmacology is of interest to the study of the history of science., it illustrates aspects of the practice of doctors and pharmacists, the status of patients, and the types of drugs