Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
إن موضوع العلاقات الحضارية بين المغرب و وادي الرافدين في عصر فجر التاريخ من المواضيع التي تعنى بإنتقال التأثيرات الحضارية العراقية إلى دول المغرب العربي عامة والمغرب خاصة . فقد إسترعى إنتباهي وجود إشارات مقتضبة أحيانا ومفصلة أحيانا أخرى عن تأثيرات في بعض الصناعات الفخارية والمعدنية والعمارة الدينية والدنيوية بين بلدان شرق البحر المتوسط والمغرب في
في ظل العولمه و التقدم التكنولوجي الهائل و الصراعات الاقتصاديه و تنافس السوق في شتي المجالات اصبح يثق علي عاتق الاداره علي جميع المستويات المؤسسيه و جميع تخصصاتها الحمل الاكبر في مواكبه تلك التغيرات ، وحيث ان نظام التعليم ينتج لنا اجيال يجب ان تواكب تلك التغيرات لتتماشي مع متطلبات السوق الحالي و المستقبلي و نظام التعليم يعد احد اهم الركائز التي تستند عليه الموارد البشريه بالنسبه للدوله و اي مؤسسه ، و من هنا ب
... Show Moreمارسَ التراث بغير قصد دوراً تحكّمياً في العلل البلاغية ، إذ أمكث في كل موضوع علّة ً في عليائها بـها يقارع وبفضلها يداول ، ممـا كفل ديمومتها وتوجّـه الخاطر إليها، ومـن تلك العلل ( العناية بالمتقدّم لأنـــه الأهمّ ) الماثلة في موضوع( التقديم والتأخير) ، فقد تركت هذه العلّة لقوّة ركائزها بصمتها بنجاح لتكون مدخلاً إلى علل أخرى في إطار مفاهيمي مستوفٍ حقائق موضوعية وهواتف نفسية يغذيها الواقع، ولكن بمتابعة نصـوص قرآ
... Show Moreتعد المتابعة أحد العناصر الأساسية في الإدارة الرياضية، حيث تسهم في تحسين الأداء وتحقيق الأهداف المنشودة ويهدف هذا التقرير إلى تسليط الضوء على دور المتابعة واهميتها في سياق الرياضة.
دراسات في قانون التجارة الدولية
Initiation in Islamic economy is the key for success and the way for advancement. It leads to the use of circumstances that through which the individual can achieve the accomplishments and gains. Once initiation spreads in the community, it will become a vivacious and that will lead to the development of its reality into the best. The Messenger (PBUH)( has encouraged imitation and the companionsshowed many imitations to deal with the economic issues that are vital to the stability of the peoples and communities and to achieve the necessary level of income and livelihood pursuant to what the Islamic economy has stipulated. Therefore, finding the ideal means to employ what Allah Almighty has endowed to humanity.
Nesrin Erbil, Çağdaş Türk şiirinin kıvançla söyliyebileceğimiz öncü bir isimdir. Gerçek aşk, ayrılık, üzüntü, sevgiliye hasretin yetiştirdiği ve olanaksızlıklara haykıran bir sesidir. O bir Türkcesine tüm zencirleri kıran engelleri aşan sevgiyle sevgiye ve sevgiliye koşan kendi başına bir yaratıcılıktır. Şiirleri Erbil kokar yumuşak saçının tellerini Altın Köprü suyuyla yıkamayı diler. Yüreği ise Gürgür Baba’dır Türkmen için yanar.
Nesrin Erbil, 1960 yılından sonra Irak’ta gelişen yeni Türk edebiyatı ve serbest şiir akımının en önde gelen temsilcisi olarak, büyük ilgi toplamıştır. Şiire karşı olan merak
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Talmud is one of the important books of the Jews, which deals with the life of the Jewish and Judaism in some detail after their book "Torah" because the Talmud explains the concepts and teachings of the Torah and Ahbars in this book often Miuge clergy Jews read the Talmud being transferred Ahbars of the teachings serve their interests and the interests of the Jewish establishment where reminds one Ahbars argument urges Jews by reading the Talmud and see the teachings and concepts and say "that reads the Torah have the reward of one who reads the
After this trip in the poetry of irony fields, which restricted to the second Abbasid poetry .it is necessary to mention the most notable results that the research reached