Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth. In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expressed significantly lower levels of miR-122 and miR-223. Furthermore, we compared the expression of these miRNAs between early-diagnosed HCC patients and healthy controls. There was a significant difference between miR-122 expression in HCC sera and healthy volunteers' sera (0.000 and 0.253, respectively), with a P value of <0.0001. Early diagnostic patients without treatment had completely deleted miR-122 expression levels, while those treated had slightly elevated levels. Clearly, miR-122 has been identified as a biomarker for early detection and follow-up of HCC treatment. HBV and HCV specimens expressed significantly lower levels of miRNA than normal samples with a P value of <0.0001. It is recommended that these findings be further investigated for diagnostic purposes. Further, these miRNAs are highly specific for diagnosing HCC, HBV, and HCV, making them valuable therapeutic indicators.
Al-sarf science is one of the most scientifically accurate and rich in branches. Because it depends on the one accent and how the changes happened inside this science (from an event associated with time or not associated). The people who create this science and were deep made a tough rule to can out of these sentences without reason. The aim of this research is to declare (The Impossible Phenomenon in the Preference Name) and this study is separated into two chapters:
Section one: it’s content of (Preference) in the base books and the scientists of linguists and the rules that authorized building in the name of Preference.
Section Two: Discussed the ways that possibly come in the name of Preference and resol
... Show Moreلا شك أن الموسيقى هي أقدر الفنون على خدمة الإنسان، وهي أرقى أنواع منشطات الحياة والصحة النفسية والعضوية، فالصحة النفسية والعضوية هي تناسق الشيء مع كل شيء الخلية مع الخلايا، والروح مع الأرواح، والإنسان مع الكون، كما تتناسق النغمة مع النغمات، والآلة مع الآلات .
This research takes its significance by referring to the participation of Arab Muslims in the knowledge of the chemical heritage, including the new writings and additions to this science; and thus made the way easy directly or indirectly for Europeans in the scientific knowledge of chemical, Starting from Khalid bin Yazid until the death of the last scientists Muslims in this area .
لا تحصى تلك الكتابات والمؤلفات التي تناولت اخلاقيات الاعمال (Business ethics) لكن الورقة الحالية التي سنقوم مخلصين بنقلها للعربية ليست مثلها أية مقالة قرأناها، فهي متفردة في اثارتها للموضوع في اطار الطروحات الفكرية لبعض رواد علم الادارة من المؤسسين الذين برزت شهرتهم في مرحلة ستينات القرن العشرين، وهم:
- W. Taylor
- I. Barnard
- F. Drucker
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Staring Of Its Philosophy And Intellectual Orientations And Ending With What Offering In Studying Rooms {Educational System} Concerning With Scientific ,Cognitive , Technological And Cultural Structures ,The Variables Inside This System More Than Constants And Preoccupation With Future More Than Past And Present .
So We Should Review The Education System Starting Of Its Philosophy Ending With Formulate The Educational Structure According To A New Standers To Estimate The Educational Outputs Within A Frame Of Behavioral Outputs Relay On Global Quality Standards Influenced By Global Quality Culture Which Make Us Along The Educational And Cul
... Show Moreتحديدات مفاهيمية في التحليل السياسي
This research aims to highlight the prophetic approach in civilized coexistence, and to show what society was like in the time of the Prophet, and specifically after the sakha and the writing of the newspaper (prophetic document) which established the rules of civilized coexistence, and there is no doubt that God almighty created all nations and different peoples according to Human nature, this difference has been recognized by the duty of coexistence and acquaintance without abolishing each other, coexistence and recognition of the other and respect for its particularities result in a state of dialogue between cultures and civilizations and paves the way for their meeting instead of clashing, as well as contributing coexistence to make
... Show MoreIn conclusion, I should mention that a lot of Alabaltrathih disappeared and no longer practiced in the present invention of alternatives to it like a game Almsra practiced by children for many generations by Almsra wooden, replaced Almsra-mail, or game Aledo.
موازين النقد في الشعر الفارسي
ABSTRACT
The Iraqi Government had used all Possible methods of financing the fiscal deficit according to the economic and Political Circumstances at the time. It had borrowed from abroad during the 1980s. Those methods of borrowing led to negative impacts on the Iraqi economy such as increased external dept burden, higher inflation rate, negative interest rate and accumulation of domestic debt.
The "Financial Management and Public Debt" law no 95/ 2004 made a great change in those methods of Financing fiscal deficit in Iraq. Before 2004, the deficit was financed by issuing Treasury Bills and selling them to the Central Bank of Iraq with a prefixed interest rate. Thus, i
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