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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Fri Nov 15 2024
Journal Name
الاستاذ
اثر القرائن وصورها في النص القراني
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The research aims to clarify the effect of evidence in interpreting verses and what are their forms related to interpretation, which every interpreter must be familiar with, along with the necessity of knowing the sciences with which the interpreter is armed in order for the true meaning and intended meaning of the Qur’anic verses to emerge. The determinants of the clues and the extent of their relationship to the Qur’anic text were also explained, and the levels of their impact in directing the meaning were identified in terms of strength, verification, clarity, generality and

Publication Date
Wed Jun 01 2005
Journal Name
Journal Of The College Of Languages (jcl)
السخرية والمفارقة في شعر احمد مطر
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السخرية والمفارقة في شعر احمد مطر

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Publication Date
Sun Apr 07 2013
Journal Name
Journal Of Educational And Psychological Researches
تشخيص الاطفال التوحديين في رياض الاطفال
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Developing disorders or ingeneral disability considered one of infortant cases which socities faces as a case with several a spects that may lead to disability . the movement of growth anf developing in the society thus the gardiauship of abnormal individuals became insisting issue which has social and human necessity .

The children of autism considered as special categories that guardian ship and care started of them inhoticeble image at the last time .

Hence, the researcher interested in this problem that made her studying it the study aimed to educte the child of autism that exist in kindergarten .the resrarcher depended on (Adel Abdullah) test for child autism that consists o

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Publication Date
Thu Jan 01 2015
Journal Name
مجلة مداد الاداب
المهارات اللغوي ودورها في التواصل اللغوي
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Publication Date
Fri Nov 15 2024
Journal Name
مجلة الاستاذ للعوم الانسانية والاجتماعية
القراءات القرآنية في مدونات العلوم الاخرى
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Publication Date
Sun Mar 26 2023
Journal Name
Arab Science Heritage Journal
حزن الأنا في الشعر النسائي العراقي
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This research seeks to show the state of the sad female self in Iraqi women's poetry, reveal its psychological potential within the text, analyze the phenomenon of sadness and explain its presence in poetic texts, show the influences of social life, the turmoil that was the main resource for the crisis of the creative woman's self and how to confront it,  explain the motives and reasons why the creative woman wrote about the sadness of herself through techniques and methods unique to her

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Publication Date
Sun Mar 26 2023
Journal Name
Arab Science Heritage Journal
الحركةُ الإعرابيَّة في فهم النَصّ القرآنيّ
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The research came to a statement in explaining the impact of movement in general in the Arabic language, as a word and sentence, in the Holy Qur’an in particular, and the Arabic syntactic movement in understanding the Qur’anic text.

  The research contained two sections. Each section has two demands, an introduction, and a preface. The most prominent titles of the research are the aspect of parsing, which is one of the characteristics of the Ḍād; the definition of parsing in language and terminology; the impact of movement on understanding the Arabic text in general; and in understanding the Qur’anic text in particular

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Publication Date
Wed Dec 20 2023
Journal Name
Arab Science Heritage Journal
الصراع الدّرامي في روايات سميرة المانع
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Praise be to God, and prayers and peace be upon the most
eloquent of those who uttered adverbs, our master Muhammad
and his family and companions, and after,,
This study has shed light on some of the fictional works of
Samira Al-Manea. It contributed in one way or another to
increasing the artistic value of the literary work, spreading in it
an emotional energy that mixed with its events

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Publication Date
Sun Oct 01 2006
Journal Name
Journal Of Educational And Psychological Researches
التكوين الاجتماعي والثقافي ودورهما في التنميةالمستدامة
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ان العلاقة بين البناء الأجتماعي والثقافي والتنمية المستدامة ، علاقة عضوية ومتبادلة التأثير ، فالبناء الأجتماعي هو أحد الأعمدة الرئيسة الذي تدور حوله عمليات التنمية المستدامة . وبالثقافة يصنع الأنسان القيم الفكرية والروحية والمادية ، ويترجم فلسفته الى أنماط سلوكية ، ومواقف حياتية ، فبغير الثقافة تبقى الموارد البشرية والطبيعية مجرد خامات أولية غير موظفة لصالح الأنسان والمجتمع . فالتنمية الأجتماعية وا

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Publication Date
Tue Jan 01 2013
Journal Name
Journal Of The College Of Languages (jcl)
LA ENSEÑANZA Y EL APRENDEZAJEDELLÉXICO ESPAÑOL ENIRAK
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El tema de esta investigación está directamente relacionado con el papel del léxico en la enseñanza-aprendizaje del español como segunda lengua en el sistema de enseñanza universitariairaquí, donde se llevó a cabo la investigación empírica y la propuesta de criterios de la selección de léxico español.

Este estudio se ha centrado concretamente en los alumnos irakíes de nivel elemental que estudian elespañol como segunda lengua extranjera. Con el fin de conocer los estilos de enseñanza-aprendizaje del vocabulario practicado en las aulas, de determinar las faltas en la selección léxica y realizar propuestas de mejorar la competencia  léxica,  hemos efectuado el an

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