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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Thu Feb 24 2022
Journal Name
Journal Of Educational And Psychological Researches
معوقات عمل المرأة في المنظمات غير الحكومية بحث ميداني
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The issue of volunteerism is one of the most important issues that have become prominent in social sciences and contemporary social thought, especially as a result of the transformations and changes that the world undergoes today. The voluntary sector has become the concern of all societies and governments for its development and service to society and various sectors. The practice of women is prominent in the work of volunteerism after 2003 in Iraq, but its work face a number of obstacles and hindrance. The problem of research is the obstacles of women's work in non-governmental organizations. The research aims to identify the nature and characteristics of volunteer work of Iraqi women.        &nb

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Publication Date
Mon Oct 22 2018
Journal Name
Arab Science Heritage Journal
الفلاسفة الفلاسفة وآراؤهم في العقل وعلاقته بالنفس والروح والقلب
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In this research  I  like  to shed  light on the mind  because  of its  importance  because  it is  what  distinguishes  Human  from all  other  animals and  that  the question  and  status  comes  from his role in the  formulation  of  knowledge  and  science  where the  machers  agreed  that  the word of  mind  in  its  general  sense  is the  source  of  thought  and  thought  and the instrument  of  faith  and  philosophy , Then to the statement  of the  various  stages  pass

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Publication Date
Sat Apr 01 2023
Journal Name
مجلة كلية بغداد للعلوم الاقتصادية الجامعة
دور استراتيجية الانتاج الانظف في حماية البيئة وتخفيض التكاليف
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ان حماية البيئة وتخفيض التكاليف من األهداف التي تسعى الوحدات االقتصادية الى تحقيقها لكي تتماشى مع التوجه العالمي لحماية الموارد الطبيعية وإنتاج منتجات صديقة للبيئة وفي الوقت نفسه التخلص من االلتزامات التي تتحملها الوحدات االقتصادية من تكاليف بيئية وغر امات مما يؤدي الى ارتفاع كلف االنتاج ، يهدف البحث الى دراسة المرتكزات المعرفية الستراتيجية اإلنتاج األنظف وتحديد التكاليف التي يمكن تخفيضها خالل مراحل اا

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Publication Date
Sun Oct 21 2018
Journal Name
Arab Science Heritage Journal
قراءة قراءة في القواعد الإعلالية وأثـــرها فـــي بـــنــيــة الكلمة
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this research talks about the weakness that had happened in the construction of the sentences which effected on the syntactic meaning . it considers an important problems faced the languages .

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Publication Date
Mon Jan 01 2018
Journal Name
حوليات كلية الآداب
الومضة في نصوص الريح لاتصادق أحدًا للشاعر لطيف هملت
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Publication Date
Tue Oct 06 2020
Journal Name
College Of Islamic Sciences
منهج الشيخ الخراساني (ت 1329هـ) في كتابه كفاية الأصول
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Conclusion

After this tour with Alkhund Al-Khurasani and his book “Adequacy of Fundamentals,” we can highlight the results we have got through what we have reviewed in the research:

  • Al-Akhund Al-Khurasani was born and raised in a scientific environment that gave him from his childhood the opportunity to gain knowledge of achievement. Therefore, he left to seek knowledge from the beginning of his youth and toured the cities, then he went  to  Tehran and then  He went  to the holy city of Najaf, then left for Samarra, then returned to Najaf in order to work on the scholars and the student. 
  • Al Akhund al-Khorasani studied on several scholars , whether in Iraq or in Geran, and he

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Publication Date
Mon Jul 01 2024
Journal Name
مجلة نسق
الإدمان في منظور قوة علم النفس الإيجابي وطرائق الوقاية
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Publication Date
Mon Dec 05 2022
Journal Name
Baghdad Science Journal
IPv6 Security Issues: A Systematic Review Following PRISMA Guidelines
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Since Internet Protocol version 6 is a new technology, insecure network configurations are inevitable. The researchers contributed a lot to spreading knowledge about IPv6 vulnerabilities and how to address them over the past two decades. In this study, a systematic literature review is conducted to analyze research progress in IPv6 security field following the Preferred Reporting Items for the Systematics Review and Meta-Analysis (PRISMA) method. A total of 427 studies have been reviewed from two databases, IEEE and Scopus. To fulfil the review goal, several key data elements were extracted from each study and two kinds of analysis were administered: descriptive analysis and literature classification. The results show positive signs of t

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Publication Date
Tue Jan 30 2018
Journal Name
مجلة جامعة الانبار للعلوم القانونية والسياسية
الحماية المدنية للمستهلك في المرحلة السابقة على التعاقد الالكتروني
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يتناول البحث الحماية المدنية للمستهلك في المرحلة السابقة على التعاقد الالكتروني

Publication Date
Thu Sep 30 2021
Journal Name
College Of Islamic Sciences
Islam's position on freedom according to John Stuart Mill
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The issue of freedom is the most prominent and distinctive issue of Western thought, which it reached after a long struggle. The English thinker John Stuart Mill is considered the most prominent Western thinker who elaborated on the issue of freedom, until his ideas on the issue of freedom became the semi-final formula for issues of freedom in Western thought, which revolve in their entirety on The individual has complete freedom as long as it does not harm others, and this freedom is controlled by law.

And if the freedoms he offered were not considered an achievement in Western thought; Freedom in Islam is a central and fundamental issue, and the details of freedoms in Islam have not been accomplished by anyone, but rather came

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