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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Sun Nov 04 2018
Journal Name
Arab Science Heritage Journal
دراسة دراسة في أعلام بغداد الأب أنستانس الكرملي أنموذجا
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The study of the Baghdad personalities is an important issue because the owners of these personalities usually belong to the elite, which play a distinct role in the development of any society in all political, economic, social and cultural fields. These include the study of the personal personality of Father Anastas Marie Carmeli to highlight many aspects of personality And his clear fingerprints on the movement of society in the field of culture and thought

    That Karamli's efforts in the field of language, literature and history made him one of the most prominent pioneers of Renaissance late in the history of modern Iraq

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Publication Date
Sun Oct 01 2023
Journal Name
مجلة قضايا سياسية
الذكاء الاصطناعي والوجود الإنساني: قراءة فكرية في الابعاد الاقتصادية
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يعد الذكاء الاصطناعي من العلوم الحديثة التي ارتبطت بالإنسان منذ العقود الخمسة الماضية، ولتصبح السياسة الرقمية الاقتصادية جزءاً لا يتجزأ من المجتمع، لكونها خرقت أغلب مجالات حياة الانسان. وهذا ما شجع صانعوا السياسات التكنولوجية الجديدة في التفكير بكيفية توظيفه لخدمة مصالحهم الاقتصادية العُليا، بغض النظر عن بذل الجهود للتفكير في مصالح الانسان الاقتصادية وتنظيمهم ومراقبة الذكاء الاصطناعي التوليدي. لقد أيقن

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Publication Date
Fri Jul 12 2019
Journal Name
Rule Of Law And Anti-corruption Center Journal
المظاهر القانونية للفساد واستراتيجية مكافحته في تعزيز قيم النزاهة
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بات الفساد ظاهرة عالمية تهدد المجتمعات وبقائها ، وبدت الانقسامات المجتمعية تتضاعف في البلدان التي ينتشر فيها الفساد بمختلف أنواعه وتسمياته ، حيث استكشفت الدراسة بأن التشريعات الجنائية حرصت على تقرير نظام عقابي خاص لمواجهة جرائم الفساد مما استوجب بنا بيان المظاهر القانونية للفساد السياسي المتمثل بالرشوة الدولية والرشوة الانتخابية لان الفساد لم يعد متعلقا بالجانب الاقتصادي فحسب بل امتد إلى الجوانب الأخرى

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Publication Date
Sun Jan 17 2021
Journal Name
Arab Science Heritage Journal
التنظيمات المالية في العصر العباسي (132-566هـ/749-1170م)
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The Abbasid Caliphate generally paid attention to the financial aspect through the collection of resources , And also in terms of spending these resources

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Publication Date
Mon Nov 19 2018
Journal Name
Arab Science Heritage Journal
تعمير تعمير الأرض وأهمية الغرس في ضوء السنة النبوية
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Islam is a religion that God wanted to be a platform emerges from human steps in various walks of devotional and economic life, etc, so it went Islam, guids human beings being as successor of God on earth.

 The result that the worship of man for the Lord, which is one of the reconstruction of the land that is the secret of the sustainability of human life on the ground, often urged the Sunnah on the reconstruction of the earth and the importance of planting them and paired the reconstruction work that obtained by the human reward which would Allah his home in the Hereafter, There construction of the earth does not involve just planting them; it takes many forms Maintaining them and not marring the form of reconstruction and

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Publication Date
Sun Jan 01 2006
Journal Name
Journal Of Educational And Psychological Researches
المسرحية بين النقل التلفزيوني والتسجيل في الأستديو (دراسة مقارنة)
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اهمية البحث والحاجة اليه :

            في بداية ظهور التلفزيون كانت البرامج المقدمة تعتمد على المنوعات والمسرحيات المنقولة من المسرح . وقد استفاد التلفزيون من الفنون التي سبقته مثل المسرح فنرى ان :

" محطات التلفزيون بادرت بتسجيل المسرحيات المتعددة لتملأ بها ساعات الارسال " [1]

            وكذلك

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Publication Date
Mon Jan 23 2023
Journal Name
Arab Science Heritage Journal
ظاهرة المفارقة في كتاب بلاغات النساء دراسة بلاغية اسلوبية
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The Arab woman expressed the life of oppression that she suffers from in her masculine environment, as she expressed her linguistic abilities with eloquence and intelligence, as she did not neglect philosophy, wisdom,

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Publication Date
Fri Feb 08 2019
Journal Name
Journal Of The College Of Education For Women
بدایات الفكر الجمھوري في العراق 1908 - 1921 دراسة تاريخية
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The main target of this research is to follow the stages of the emergence of
the idea of republican form of government from its very beginning , yet there
were many elements from different estates thinker , educated , few of heads of
clans . This first opportunity for the mobilization of politically-minded people
with fundamental activity like najei shokat . hussain al-rahal notable poet maruf
al-rasafi those who formed what so called the political elite who believed in
constitutional , democratic parliamentary republic , one of them was al-rahal who
called for a constitutional republic even before the emergence of the
constitutional movement in Iran and ottoman empire (1908).
The holy najaf become cultural cen

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Publication Date
Mon Jul 22 2019
Journal Name
Arab Science Heritage Journal
رؤية حضارية لمناهج الفكر الفلسفي واتجاهاته في المشرق الإسلامي
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This research involves the civilized vision of the trends and approaches of philosophical thought in the Islamic Orient, whose objectives were to show Islamic philosophy and the pioneers of thought in it and the most important products that crystallized after its emergence in the Islamic world

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Publication Date
Mon Dec 01 2008
Journal Name
Political Sciences Journal
العلوم السياسية في العراق بداياتها ، نشأتها ، تطورها ، ومفرداتها التدريسية
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العلوم السياسية في العراق بداياتها ، نشأتها ، تطورها ، ومفرداتها التدريسية

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