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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Tue Nov 13 2018
Journal Name
Arab Science Heritage Journal
المجتمع المجتمع الاسكندري: عاداته وتقاليده الاجتماعية في العصر المملوكي
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It is important to study that the social circumstances in Alexandria through  Mamluk era specially social life in Egypt specially in Alexandria  which had describe as it was show change in opposite with other sides of life

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Publication Date
Thu Jun 01 2006
Journal Name
Journal Of The College Of Languages (jcl)
Модальные частицы и их значения и происхождения в современном русском языке
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Модальные частицы это служебные слова, которые служат в
предложении для выражении различных оттенков значений и
представляют собой продукт сложных изме- нений грамматического
строя русского языка.
Явно категория модальных частиц тесно соприкасается с
частями речи и частицами ((Модальность в русском языка
выражается формами наклонений, а так же лексическими
средствами-модальными словами и

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Publication Date
Wed Oct 31 2018
Journal Name
Arab Science Heritage Journal
حوار حوار الانبياء في القرآن الكريم-دراسة اسلوبية مقارنة
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اسلوب الحوار في القرآن الكريم اسلوب حياة وفي حقيقة الامر يضم القرآن الكريم بين دفتيه حوارات كثير مابين الله عزوجل وخلقه وما بين الانبياء واقوامهم وما بين الانبياء والطواغيت ومابين المؤمنين والكفار وهكذا ، وبدء الخلق قام على حوار مابين  الله عزوجل وآدم وما بين آدم وابليس وما بيا الله جل وعلا والملائكة .

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Publication Date
Wed Nov 28 2018
Journal Name
Arab Science Heritage Journal
الصناعة الصناعة في بغداد للفترة (334هـ /935م -555هـ/ 1160م)
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The industries in Baghdad, the most important economic activities in the era albeit and Seljuk to the availability of manpower and resources which encourage the establishment of these industries in Baghdad.

These industries seam as simple crafts, but they may have influenced the nature of the social and economic life in the Baghdadi community during the foreign authority on Iraq and general in Baghdad in particular.

 

 

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Publication Date
Thu Aug 27 2020
Journal Name
Arab Science Heritage Journal
تعالق النص القرآني في شعر كعب بن مالك الأنصاري
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     The Qur'an was revealed with a clear Arabic tongue, and it seized minds, and was astonished by its eloquence and eloquence of tastes, so it was a new dawn, and a nucleus for the birth of a new literature inspired by the tolerant thought of Islam, its fresh words, and its delicate and revealing meanings

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Publication Date
Sun Apr 01 2012
Journal Name
Journal Of Educational And Psychological Researches
الأوضاع النفسية والإجتماعية لنساء الأقليات في العراق )دراسة ميدانية(
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The study present a detailed description of the new violent situation that those women faced after 2003 in Iraqi society and the effect of such violence and security breaking down on minority women perception and feeling of bonding or adaptation with this society and how they look to the aaceptance of the society to them and their minority group as a whole. In addition to the impact of these social changes after 2003,on the women rights and personal freedom. One of the aims of the study is to provide data base to be used when efforts present to put a policies or programs for supporting the minority women. Another aim is to point out and define the violations commited on the rights of those women. The field survey included 2100 women from

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Publication Date
Wed Oct 01 2008
Journal Name
Journal Of Educational And Psychological Researches
برنامج لتقويم اداء رؤساء الاقسام العلمية في الجامعات العراقية
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مشكلة البحث

       لقد حدا بالمهتمين في الميدان التربوي، والادارة التربوية بصورة خاصة، ان يجدوا علاقات ايجابية بين متغيرات الميدان التربوي عامة والاداري بصورة خاصة وقد تمخض هذا عن وجود علاقة ايجابية بين اداء المديرين ورؤساء الاقسام ودرجة التقويم، ومن هنا يتضح انه كلما كان التقويم عالياً في درجته، يتضح ان هناك اداءً فاعلاً ولكن ليس بالشكل الحقيقي لمعنى التقويم ما لم يكن هناك

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Publication Date
Thu Nov 08 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
المشكالت الصحية المرافقة لالستخدام الخاطئ للحاسوب في مدينة بغداد
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The Research aimed for identification the significant of health problems that occurrences through
misused of computer for those whom attaches with more than two hours daily and to identification the
nature of demographical characteristics variables and that related variables with using computer. Also to
know the level of user’s knowledge for some attaché’s equipment's and finally creating a new suggested
measurement scale for studying health problems that were occurred through misused of computer.
Creating questionnaire includes several domains (Social problems – family environment, Social problems –
external environment, some health problems attaches with related equipment's, psychological problems,
and hea

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Publication Date
Thu Dec 13 2018
Journal Name
Arab Science Heritage Journal
صك صك الرزق في القرن الأول الهجري(البطاقة التموينية)
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 The government gave the muslims additional things to the sum of money ,it was al rizq which was given to the mujahidin .

   Those who distributed the ata where called al urafa ,they were from the best biography people

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Publication Date
Wed May 05 2021
Journal Name
Arab Science Heritage Journal
تربية الشباب في التراث الاسلامي وانعكاساتها على الواقع المعاصر
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Islam paid great attention to the youth, and took care of them because they
are the strength and movement, which is the preferrence stage in human life,
and they are the ones who

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