Zerumbone is a well-known compound having anti-cancer, anti-ulcer, anti-inflammatory and anti-hyperglycemic effects. During its use for the disease treatment, the membrane of erythrocyte can be affected by consumption of this bioactive compound. The current study was the first report of investigation of the hemolytic activities on human erythrocytes and cytotoxic profile of zerumbone. The toxicity of zerumbone on human erythrocytes was determined by in vitro hemolytic assay. Brine shrimp lethality assay was used to evaluate the cytotoxic effect of zerumbone at concentrations 10, 100 and 1000 μg/mL. The human erythrocyte test showed no significant toxicity at low concentrations, whereas hemolytic effect was amplified up to 17.5 % at the highest concentration. The half lethal concentration (LC50) value of zerumbone against brine shrimp was less than 1000 µg /mL (LC50=190 µg/ml) showing the significant toxic nature of this compound. These results provide a baseline in terms of the toxicity of therapeutic formulations from this compound to membrane erythrocytes with a great attention to the highest concentrations, which paves promise for drug development.
الملخص (باللغة العربية) شكّل اجتياح العراق للكويت في 2 آب/أغسطس 1990 اختباراً حاسماً لقدرة جامعة الدول العربية على إدارة الأزمات الإقليمية وصياغة موقف عربي موحّد إزاء انتهاك واضح لسيادة دولة عضو. غير أن أداء الجامعة خلال أزمة الخليج الثانية كشف عن حالة من الشلل المؤسسي والإجرائي، تجلّت في بطء اتخاذ القرار، وتنازع التأويلات حول شرعية الإجراءات، وتوظيف نصوص الميثاق بما أعاق إنتاج قرار عربي حازم وقابل للتنفيذ. تن
... Show MoreThe aim of this research is to make a new investigation of a scientific thesis in Arabic Morphology in which an allusion occurred in relation to its real author and its title, there is alot of dropping and flaw when it was first applied due to depending on one written transcript
هدف البحث الى التعرف على القياس المحاسبي عن التنمية المستدامة، وبيان العلاقة بين القياس المحاسبي عن التنمية المستدامة وتقارير الابلاغ المالي، وكذلك بيان أثر القياس المحاسبي عن الاستدامة على تقارير الإبلاغ المالي في الشركة العامة للمنتوجات الغازية، وقد تمحورت مشكلة البحث في بيان أثر عناصر المحاسبة عن التنمية المستدامة، البيئية، والاجتماعية، والاقتصادية، على تقارير الإبلاغ المالي في الشركة العامة للمنتو
... Show Moreهدف ال الأسلوب المعرفيّ م الإد ا ركيّ اضة للبنات، والتعرّف على علاقة التنظ ة وعلوم الر ة البدنّ ة التر لّ ة في ات المرحلة الثانّ طال إنّه احثتان اضة للبنات، وأفترضت ال ة وعلوم الر ة البدنّ ة التر ل ة في ات المرحلة الثان عض طال التأمّليّ الاندفاعيّ لدى اس الأسلوب المعرفيّ التأمّليّ الاندفاعيّ لدى عیّنة م الإد ا ركيّ ونتائج مق اس التنظ ة بین نتائج مق
... Show MoreThe research aim to know the effect of note–taking by computer method as amentalactivators in achievement of physics subject for the first intermediate class students.
To investigate from aim of the research the research sample was chosen from the first intermediate class students in Al–mutamyzat secondary school for girls. Which belongs to the general administration for the second karkh education which randomly chosen from (9) schools for distinct female students in Baghdad. Then randomly chosen two sections form three about (80) female students at (66.667%) from total sample it’s about (120) female student in the three sections. The randomly chosen too, section (a) to represent experimental group it’s about (41) female
... Show MoreAbu Al- Qasim Qa ,im Maqam is famous figure in political life of lranian; The life of Abu Al- Qasim Qa ,im Maqam is full of incidents and conflicts in the period of the expansion of foreign influence in lran Abu Al- Qasim Qa ,im Maqam has an important role in the history of Iran Modern political considered him one of the most prominent leaders to the unified Arabian nationalistic liberating Abu Al- Qasim Qa ,im Maqam raised in the history of the Qajar .
شغلت قضية اعداد المعلم اهتمامات العديد من المسؤولين في قطاع التربيه والتعليم وكذلك اولياء امور الطلبه واساتذه الجامعه , ولازالت الهم الاكبر , وذلك لاختلاف سياسه اعداد المعلم من دولة واخرى وحسب الفلسفه التربويه والمتغيرات والتطورات السريعه التي يشهدها العالم
وفي ضوء ماتقدم , ان المعلم هو احد عناصر العمليه التربويه في اي بلد . بعد الطالب والمنه
... Show MoreProblem: Find dimensions of the problem by answering the following question: what the effect of using the Six Thinking Hats strategy to acquire the historical concepts and retain the fourth-grade students in the subject of literary history. Importance of research: current research is gaining importance in many ways, including: 1. Keep pace with the new in the field of education and modern educational strategies. 2. Shed light on innovative education strategy in the teaching of history, which is one of the materials that need to renew the tragedy of instruction methods for students. 3. Out of the monotony and traditional way of teaching to a method and a new strategy to develop the teacher and the learners thinking skills through various
... Show More