The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
درست الباحثة البنية الإيقاعية عند الشاعر الصقلي
Resumen
Este trabajo de investigación ofrece uno de los temas relevantes en la lengua, el cual es estudiar las dimensiones sintácticas, semánticas y pragmáticas de las preposiciones, en general, y de las dos preposiciones "Para" y "Por" en concreto, en una unidad linguística más amplia que la llamada "Oración". En la parte referida al estudio de las dos preposiciones mencionadas, estudiamos sus distntos usos funcionales, usos que se acercan, unas veces, entre sí y se alejan en otras.
Abstract
... Show MoreAbstract The present research aims to know the range of Knowledge and the using of teachers of aerography department in colleges of Education to Applicant electronic Learning , So the Sample of the research reached (129) teacher, of the university of Boghdad and Al mustansiria who were chosen by using Randomly sample , and applauding questioner for these perpos that prepared by muhamed bn Ghazi Al Judi – and by using the T-test for one sample and person correlation formula as a statistical means. The research reached to the results which indicate that weakness knowledge and using the theachers of geographe department to the application electronic learning. And according this the researcher put some Recommendation and suggestions.
... Show Moreاثر التواجد العسكري الامريكي على النظام السياسي في العراق
The subject of the research is the collective words = Jawami Al-kalim. Those who wants to know this subject to be aware of the benefit of "Al-Ejaz and Al-iktisar " and to cover the Rhetoric of signal should think carefully the abbreviations because the collective words because it is the a face of the important faces represented by the abbreviation of shortness as it is and old subject where it can be found in every source of rhetoric books which were old or modern. But what attracts attention is that this subject did not take all its range in study in the way that discover its beauty concerning style, words, sentences and meaning. This cause
... Show Moreيهدف البحث التعرف على اثر استراتيجية القوائم المركزة في تحصيل مادة الكيمياء عند طلاب الصف الثاني المتوسط وتم استخدام المنهد التجريبي ذو الضبط الجزئي وكذلك تم اختيار مجامع البحث جميع طلاب المدارس الثانوية والمتوسطة التابعة لمديرية تربية كربلاء