The biomarker significance of three chemokines (CXCL8, CXCL10 and CXCL16) was evaluated in sera of 45 breast cancer (BC) and 28 benign breast lesion (BBL) patients, as well as 20 control women. Clinical stage and tumor expression of estrogen (ER), progesterone (PgR) and human epidermal growth factor receptor-2 (HER-2) receptors were considered in this evaluation. The results demonstrated that CXCL8, CXCL10 and CXCL16 showed a significant increased median in BC and BBL patients compared to control (CXCL8: 47.3 and 25.7 vs. 15.0; CXCL10: 37.6 and 30.7 vs. 13.1; CXCL16; 27.9 and 25.2 vs. 19.2 pg/ml, respectively). The increased levels of CXCL8 and CXCL16 were more pronounced in triple-negative and HER-2 positive patients, respectively. Binary logistic regression analysis revealed that CXCL8 was a significant predictor of BC, and such prediction was more depicted in triple-negative patients. The receiver operating characteristic analysis also revealed that CXCL8 recorded an area under curve of 0.998 in BC patients. In conclusion, CXCL8 is a potential biomarker for BC, especially when ER, PgR and HER-2 expression is considered. In this context, the predictive significance of CXCL8 in influencing BC progression is suggested in triple-negative patients.
The wall of Eastern side considers one of the important prominence architect sign of Baghdad city through Abbasid era , it is surrounded by many shops, houses , the work had started in the period of caliph( Al-Mustathher Billah )
سار العباسيون على نفس النهج الذي كان عليه الأمويين في كثير من الانظمه والتقاليد والسياسات على الرغم من إن الدولة العباسية كانت تمثل بداية لعصر جديد في تاريخ الإسلام(1)،ومن تلك الأنظمة التي ورثوها عن الأمويين وطوروها هي اهتمامهم بالنظام الزراعي منذ بداية قيام دولتهم وهنا سنحاول تقديم بعض الانجازات
دور مكننة المعلومات المحاسبي في اتخاذ القرارات
This research is an attempt to prove the scientific tendency in the Islamic philosophical heritage through a review of the most important ideas of intellectual and philosophical theories brought by the philosophers of this
All praise be to Allah, Lord of the worlds, and prayers and peace be upon the most honourable of the prophets and messengers, our beloved Muhammad, and on his family and companions until the Day of Judgment
الفيدرالية : نظرة في منطلقاتها الفكرية وآفاقها المستقبلية
العلوم الاجتماعية في جامعة بغداد .. التاريخ والتطورات
ادى انتشار الاسلام وانتعاش الاوضاع الى تطور السياحة البحرية
many painters tried to mix colors with Music by direct employment through colorful musical pieces or the use of multiple instruments and techniques , or vice versa, including the French artist )Robert Stroben(, he transferred the piece of music to be depicted on the painting and worked on the tones of music (Johann Sebastian Bach) by dropping the color on the lines of the musical scale, for example (the C tone) ranging from brown to red ( Tone La A) from gray to orange, and so on, the presence of links and similarity factors between the world of music and the world of colors facilitated the process of linking musical notes with colors, the most famous of which was presented by the world (Newton) in the circle of basic colors and linking
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