Researcher Image
رند رياض حافظ خالد - Rand R. Hafidh
PhD - assistant professor
College of Medicine , Microbiology
[email protected]
Summary

 Coarse specialization: Medical Microbiology.  Fine specialization: Medical Biotechnology.

Qualifications

 Graduated at the College of Science/Biology department/ University of Baghdad for the academic year 1998/1999. Obtained the B.Sc degree in Biology/Microbiology branch with a grade good and an average of 75.30 on 10-7-1999 from the first sitting. Serial (Rank) 12 among 184 for the two sittings.  Master Degree (M.Sc in Medical Microbiology) from College of Medicine/Al-Nahrain University 2004 (formerly known as Saddam College of Medicine that belongs to Saddam University).  Doctor of Philosophy (Ph.D in Medical Biotechnology) from Institute of Bioscience/University Putra Malaysia 2011.

Responsibility

 Current position (Nov. 2004 up to date): Assistant Professor at the department of Medical Microbiology, College of Medicine, University of Baghdad / Baghdad-Iraq.  Current position (March 2017 up to date): Manager of the Division of quality assurance and academic performance, College of Medicine, University of Baghdad / Baghdad-Iraq.  Current position (June 2023 up to date): Editor Manager of Journal of the Faculty of Medicine, College of Medicine, University of Baghdad/ Baghdad-Iraq.  Previous position (2004 to 2007): Researcher at the Biotechnology and Research Center of Al-Nahrain University/ Baghdad-Iraq.  Previous position (1999 to 2001): Demonstrator in the College of Science/Biology department/University of Baghdad/ Baghdad-Iraq.

Awards and Memberships

Awards:

  1. Gold Medal: Bactericidal Effects of Mung Bean Sprout Against Multidrug (MDR) Resistant Bacteria. PAMERAN REKA CIPT, PENYELIDIKAN DAN INOVASI. 19th-21st July 2011. Pusat Kebudayaan dan Kesenian Sultan Salahuddin Abdul Aziz Shah, University Putra Malaysia, Serdang, Selangor, Malaysia.
  2. Higher Education Award for Scientific Sciences. 30th December 2013. University of Baghdad, Baghdad, Iraq.
  3. Higher Education Award for Scientific Sciences. 18th May 2014. University of Baghdad, Baghdad, Iraq.
Research Interests

 Medical microbiology (bacteriology, virology, and mycology), tissue culture, cell line, antimicrobial activity, anticancer activity, phage therapy, molecular biology.

Academic Area
  1. Rand R. Hafidh, Nidhal Abdul Muhaimen, Rasool Dabbagh. 2004. Cell Mediated Immunity in Dermatophytoses. Iraqi Postgraduate Medical Journal. 3(3): 296-300, 2004.

  2. Rand R. Hafidh, Rasool Dabbagh, Nidhal Abdul Muhaimen. Prevalence of Dermatophytic Skin, Nail and Hair Infection in Baghdad-Iraq. Iraqi Postgraduate Medical Journal. 3(4): 328-330, 2004.

  3. Rand R. Hafidh, Rasool Dabbagh, Nidhal Abdul Muhaimen. Dermatophytoses Clearance Depends on Cell Mediated Immunity Response. Iraqi Postgraduate Medical Journal. 4(4): 352-355, 2005.

  4. Rand R. Hafidh, Rasool Dabbagh, Nidhal Abdul Muhaimen. Atopy as a Risk Factor for Dermatophytoses. Almustansiriya Journal of Pharmaceutical Sciences. 2(1): 25-28, 2005.

  5. Rand R. Hafidh, Nidhal Abdul Muhaimen, Rasool Dabbagh. Dermatophytoses and the high level of CR3 (CD11b/CD18). Almustansirya Journal of Pharmaceutical Sciences. 2(2): 14-17, 2005.

  6. Rand R. Hafidh, Nidhal Abdul Muhaimen, Rasool Dabbagh. Immunosuppressive Serum Factors in Patients with Dermatophytoses. Almustansirya Journal of Pharmaceutical Sciences. 2(2): 67-71, 2005.

  7. Rand R. Hafidh and Ahmed S. Abdulamir. Cladosporium spp. as a causative agent of white superficial onychomycosis. The Eastern Mediterranean Health Journal. 14(1): 231-233, 2008.

  8. A.S. Abdulamir, R.R. Hafidh, L.K. Mahdi, T.R. Al-jeboori, F. Abubaker, and K.A. Abbas. The Interplay between p53 and p21 Tumor Suppressor Proteins in the Transformation of Colorectal Adenoma to Carcinoma. American Journal of Immunology. 4(1): 14-22, 2008.

  9. A.S. Abdulamir, R.R. Hafidh, N. Abdulmuhaimen, F. Abubaker and K.A. Abbas. Better Understanding of the Immunosuppressive Link between the Lymphocytic Immune Cells and the Decreased Cell Mediated Immunity in Head and Neck Cancer Patients. American Journal of Immunology. 4(1): 25-31, 2008.

  10. Abdulamir, A.S., Hafidh, R.R., Abdulmuhaimen, N., Abubakar, F., Abbas, K.A. The distinctive profile of risk factors of nasopharyngeal carcinoma in comparison with other head and neck cancer types. BMC Public Health. 8: 400, 2008.

  11. Khadim HS, Abdulamir, AS., Hafidh RR., Abubakar F., Abbas K. Investigations in the molecular events of transitional cell carcinoma of the bladder. AMJ Bioch. Biotech. 4(4): 408-415, 2008.

  12. Abdulamir, A.S., Hafidh, R.R., Abubakar, F., Abbas, K.A. Changing survival, memory cell compartment, and T-helper balance of lymphocytes between severe and mild asthma. BMC Immunol. 9: 73, 2008.

  13. Hafidh RR, Abdulamir AS, Abu Bakar F, Abas F, Jahanshiri F, Sekawi Z. Antioxidant research in Asia in the period from 2000-2008. American Journal of Pharmacology and Toxicology. 4(3): 48-66, 2009.

  14. Hafidh, RR, Abdulamir, AS, Jahanshiri, F. Abas, F. Bakar, Sekawi, Z. Asia is the Mine of Natural Antiviral Products for Public Health. The Open Complementary Medicine Journal. 1: 58-68, 2009.

  15. Rand R. Hafidh, Faridah Abas, Ahmed S. Abdulamir, Fatemeh Jahanshiri, Fatimah Abu Bakar and Zamberi Sekawi. A Review: Cancer Research of Natural Products in Asia. International Journal of Cancer Research. 5: 69-82, 2009.

  16. Abdulamir AS, Hafidh RR, Abu Bakar F, Abbas K. Novel Epstein-barr virus immunoglobulin G-based approach for the specific detection of nasopharyngeal carcinoma. American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 31(6): 410-417, 2009.

  17. Abdulamir, A.S., Hafidh, R.R., Abubakar, F. Different inflammatory mechanisms in lungs of severe and mild asthma: crosstalk of NF-kappa-B, TGFbeta1, Bax, Bcl-2, IL-4 and IgE. Scand J Clin Lab Invest. 69: 487-495, 2009.

  18. Abdulamir, A.S., Kadhim, H.S., Hafidh, R.R., Ali, M.A., Faik, I., Abubakar, F., Abbas, K.A. Severity of asthma: the role of CD25+, CD30+, NF-kappaB, and apoptotic markers. J Investig Allergol Clin Immunol. 19: 218-224, 2009.

  19. Abdulamir, A.S., Hafidh, R.R., Mahdi, L.K., Al-jeboori, T., Abubaker, F. Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma. BMC Cancer 9: 403, 2009.

  20. Abdulamir, A.S., Hafidh, R.R., Kadhim, H.S., Abubakar, F. Tumor markers of bladder cancer: the schistosomal bladder tumors versus non-schistosomal bladder tumors. J Exp Clin Cancer Res. 28: 27, 2009.

  21. AS Abdulamir, FY Moghadam, RR Hafidh, Fatimah Abubakar, Latif I kadhim. 2009. Lectin Histochemistry Assay in Colon Tissues for Characterization of rodents. Proc. 4th ASVP Conf. & Ann Meeting TAVLD. pp. 376-377 published in the Thai Journal of Veterinary Medicine Vol. 39 No. 4 2009.

  22. RR Hafidh, AS Abdulamir, F Abubakar. 2009. Comparative Histological and Histochemical Inter-species Investigation of Mammalian Submandibular Salivary Glands. Proc. 4th ASVP Conf. & Ann Meeting TAVLD. pp. 384-385 published in in the Thai Journal of Veterinary Medicine Vol. 39 No. 4 2009.

  23. Abdulamir, A.S., Hafidh, R.R., Bakar, F.A. Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1, COX-2, and IL-8. Mol Cancer. 9: 249, 2010.

  24. Abdulamir AS, Hafidh, RR, Abubakar F. In vitro immunogenic and immunostimulatory effects of zwitterionized 23-valent pneumococcal polysaccharide vaccine compared with nonzwitterionized vaccine. Current therapeutic research. 71:60-77, 2010.

  25. Rand R. Hafidh, A.S. Abdulamir, Law Se Vern and Fatimah Abu Bakar. The Inhibition of Human Pathogens: Trichophyton rubrum and Trichoderma harzianum by a Natural Product. American Journal of Biochemistry and Biotechnology. 6 (1): 40-46, 2010.

  26. Rand R. Hafidh, Abdulamir AS, Law Se Vern, Fatimah Abu Bakar, Faridah Abas, Fatemeh Jahanshiri and Zamberi Sekawi. Novel in vitro antimicrobial activity of Vigna radiata (L.) R. Wilczek against highly resistant bacterial, and fungal pathogens. Journal of Medicinal Plants Research. 5(16): 3606-3618, 2011.

  27. Rand R. Hafidh, Ahmed S. Abdulamir, Law Se Vern, Fatimah Abu Bakar, Faridah Abas, Fatemeh Jahanshiri and Zamberi Sekawi. Inhibition of Growth of Highly Resistant Bacterial and Fungal Pathogens by a Natural Product. The Open Microbiology Journal. 5: 96-106, 2011.

  28. Ahmed S Abdulamir, Rand R Hafidh, Fatimah Abu Bakar. The association of Streptococcus bovis/gallolyticus with colorectal tumors: The nature and the underlying mechanisms of its etiological role. Journal of Experimental & Clinical Cancer Research. 30:11, 2011.

  29. Hafidh RR, Abdulamir AS and Abu Bakar F. Phenotype microarray profiling of the antibacterial activity of red cabbage. Functional Foods in Health and Disease. 2(6):212-227, 2012.

  30. Rand R Hafidh, Ahmed S Abdulamir, Fatimah Abu Bakar, Farid Azizi Jalilian, Faridah Abas and Zamberi Sekawi. Novel molecular, cytotoxical, and immunological study on promising and selective anticancer activity of Mung bean sprouts. BMC Complementary and Alternative Medicine. 12:208, 2012.

  31. Abdulamir AS, Hafidh RR, Abu Bakar F. The tumoricidal activity of Salmonella and its role in treating cancers. Cancer Therapy. 8: 10-23, 2013.

  32. R.R. Hafidh, A.S. Abdulamir, F. Abu Bakar, F.A. Jalilian, F. Jahanshiri, F. Abas, Z. Sekawi. Novel anticancer activity and anticancer mechanisms of Brassica oleracea L. var. capitata f. rubra. European Journal of Integrative Medicine. 5: 450–464, 2013.

  33. Rand R Hafidh, Ahmed S Abdulamir, Fatimah Abu Bakar, Zamberi Sekawi, Fatemeh Jahansheri and Farid Azizi Jalilian. Novel antiviral activity of mung bean sprouts against respiratory syncytial virus and herpes simplex virus −1: an in vitro study on virally infected Vero and MRC-5 cell lines. l. BMC Complementary and Alternative Medicine. 15:179, 2015.

  34. Ahmed Sahib Abdulamir, Sabah A. A. Jassim, Rand R. Hafidh and Fatimah Abu Bakar. The potential of bacteriophage cocktail in eliminating Methicillin-resistant Staphylococcus aureus biofilms in terms of different extracellular matrices expressed by PIA, ciaA-D and FnBPA genes. Ann Clin Microbiol Antimicrob.14:49, 2015.

  35. Hafidh, Rand R.. A comprehensive anticancer molecular study for genistein the promising anticancer drug. Journal of Contemporary Medical Sciences. 3(11): 264-269, 2017.

  36. Hafidh R.R., Hussein S.Z., MalAllah M.Q., Abdulamir A.S., Abu Bakar F. A high-throughput quantitative expression analysis of cancer-related genes in human HepG2 cells in response to limonene, a potential anticancer agent. Curr Cancer Drug Targets. 18, 2018.

  37. Jasim HN, Hafidh RR, Abdulamir AS. Formation of therapeutic phage cocktail and endolysin to highly multi-drug resistant Acinetobacter baumannii: in vitro and in vivo study. Iran J Basic Med Sci. 2018; 21:1100-1108.

  38. Sabah A.A. Jassim, Rand R. Hafidh, Zahraa Q. Ali, Ahmed S. Abdulamir. Rapid Detection of Enterohaemorrhagic E.coli Using Phage-Based Bioluminescent Assay. Journal of Clinical and Diagnostic Research. 12(11): DC05-DC08, 2018.

  39. HAFIDH, Rand R.; IBRAHIM, Basim M. Irritable Bowel Syndrome an Overview on Risk Factors and Microorganisms Role; A critical review. Iraq Medical Journal, v. 3, n. 4, dec. 2019.

  40. Abdulamir AS, Hafidh RR. The Possible Immunological Pathways for the Variable Immunopathogenesis of COVID—19 Infections among Healthy Adults, Elderly and Children. Electron J Gen Med. 2020; 17(4):em202.

  41. Rand R. Hafidh, Ahmed S. Abdulamir. The anticancer molecular mechanism of Carnosol in human cervical cancer cells: An in vitro study. AsPac J. Mol. Biol. Biotechnol. 2020; 28(3): 88-98.

  42. Shaymaa Husham Ahmed, Rand R. Hafidh. The Isolation of specifically lytic phages along with their extracted endolysins as antibacterial agents to MDR Enterococcus faecalis. Research J. Pharm. and Tech. 2021; 14(9): 4547-4554.

  43. Jassas MN, Hafidh RR. Characterization of the Antibacterial, Antibiofilm Activities, and Genetic Structure of Endolysin Extracted from Enterococcus faecalis Phage. International Journal of Drug Delivery Technology. 2021;11(3):817-826.

  44. Ali Nayyef Umayra, Jabbar S. Hassan, Rand R. Hafidh, Thanaa R. Abdulrahman. Detection of Extended-spectrum β-lactamases Genes in the Zoonotic Brucella abortus. Azerbaijan Medical Journal. 2022; 62(6): 2653-2659.

  45. Basim M. Ibrahim, Rand R. Hafidh and Sarmad M. Zainy. Molecular Identification of Dermatophytes by Arbitrarily Primed Polymerase Chain Reaction. AIP Conference Proceedings 2398, 040037 (2022); https://doi.org/10.1063/5.0093617.

  46. Rand R. Hafidh, Zahraa Q. Ali and Ahmed S. Abdulamir. Autophagy or Apoptosis: Anticancer Molecular Mechanism of Epigallocatechin Gallate with Natural Polyphenol Effect on HepG2 Cells Viability. Iraqi J Pharm Sci, 2023; 32( 1 ): 167-176.

  47. Emad R, R. Hafidh R, Zukhrufuz Zaman M. Identification of Klebsiella oxytoca by VITEK-2 System in Baghdad Hospitals. JFacMedBagdad. 2024; 65(4).

        Published Books’ Chapters:
    
  48. A.S. Abdulamir, R.R. Hafidh and F. Abubaker. 2012. The Novel Use of Zwitterionic Bacterial Components and Polysaccharides in Immunotherapy of Cancer and Immunosuppressed Cancer Patients. In: Advancements in Tumor Immunotherapy and Cancer Vaccines. Hilal Arnouk (eds), pp: 155-174. InTech, Rijeka, Croatia. https://www.intechopen.com/books/advancements-in-tumor-immunotherapy-and-cancer-vaccines

  49. Abdulamir A.S., Muhammad Zukhrufuz Zaman, Hafidh R.R. and Abu Baker F. 2012.The Role of Diet, Prebiotic and Probiotic in the Development and Management of Inflammatory Bowel Diseases (IBD). In: Inflammatory Bowel Disease Advances in Pathogenesis and Management. Sami Karoui (eds), pp: 249-274. InTech, Rijeka, Coratia. https://www.intechopen.com/books/inflammatory-bowel-disease-advances-in-pathogenesis-and-management

  50. A.S. Abdulamir, R.R. Hafidh and F. Abubaker. 2012. Streptococcus bovis/gallolyticus Induce the Development of Colorectal Cancer. In: Colorectal Cancer Biology From Genes to Tumor. Rajunor Ettarh (eds), pp: 375-390. InTech, Rijeka, Croatia. https://www.intechopen.com/books/colorectal-cancer-biology-from-genes-to-tumor -link of the books’ chapters by the author Rand Hafidh (IntechOpen) http://www.intechopen.com/chapters/78690

Teaching materials
Material
College
Department
Stage
Download
Clinical Laboratory Sciences
كلية الطب
الاحياء المجهرية
Stage 2
Infectious Diseases
كلية الطب
الاحياء المجهرية
Stage 3
Teaching

Clinical Laboratory Sciences; Infectious Diseases; Virology; Systemic and Diagnostic Bacteriology;

Supervision

Five M.Sc students

Publication Date
Mon Jan 01 2024
Identification of Klebsiella oxytoca by VITEK-2 System in Baghdad Hospitals
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Background: Klebsiella oxytoca is a Gram-negative rod-shaped bacterium that is becoming resistant to multiple drugs and is frequently endangering patients' lives. It is a member of the human microbiota.

Objectives: To assess the value of identifying K. oxytoca using an automated diagnostic system (VITEK-2) as compared to traditional manual methods.

Methods: From July to November 2022, 136 clinical specimens were collected from patients in Baghdad hospitals. The VITEK-2 system was used to recognize the isolated bacteria to the genus and species levels. The biochemical indole test was used as a confirmatory test at the species level.

Results:

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Publication Date
Sat Jan 01 2022
Journal Name
Aip Conference Proceedings
Molecular identification of dermatophytes by arbitrarily primed polymerase chain reaction
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Publication Date
Sat Jun 01 2024
تقديرالتأثير التآزري خارج الجسم الحي ل اندوليسين العاثيات مع الفانكومايسين على العزلات المحلية العراقية ل Enterococcus faecalis
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من المعروف أن المكورات المعوية البرازية تسبب العديد من الالتهابات الخطيرة مع طفرة في تطور سلالات مقاومة للمضادات الحيوية ، وخاصة إلى الفانكومايسين. العاثيات البكتيرية وأنزيمات الإندوليسين الخاصة بها لديها القدرة على التأثير على خلايا بكتيرية معينة وتحليلها مما يجعلها علاجا بديلا ممكنا للسلالات المقاومة للمضادات الحيوية.

هدفت الدراسة على تقديرالتأثير التآزري للعاثية / خليط العاثية / الإندوليسين مع ف

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Publication Date
Fri Jun 16 2023
Autophagy or Apoptosis: Anticancer Molecular Mechanism of Epigallocatechin Gallate with Natural Polyphenol Effect on HepG2 Cells Viability
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Background: The anticancer impact of Epigallocatechin gallate (EGCG) the highly active polyphenol of green tea was abundantly studied.  Though, the exact mechanism of its cytotoxicity is still under investigation. Objectives: Hence, the current study designed to investigate the molecular target of EGCG in HepG2 cells on thirteen autophagy- and/or apoptosis- related genes. Methods: The apoptosis detection analyses such as flow cytometry and dual apoptosis assay were used. The genes expression profile was explored by the real-time quantitative-PCR. Results: EGCG increases G0/G1 cell cycle arrest and the real-time apoptosis markers proteins leading to stimulate apoptos

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Publication Date
Thu Nov 14 2024
Journal Name
Journal Of Emergency Medicine, Trauma And Acute Care
Novel isolation and optimization of anti-MRSA bacteriophages using plaque-based biokinetic methods
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Background: MRSA (methicillin-resistant Staphylococcus aureus) is a global health problem. Many people are looking for new ways to combat MRSA, for example by using bacteriophages (phages). It has been extremely challenging to isolate a sufficient quantity of lytic anti-MRSA phages. Therefore, new techniques for separating, refining, and reworking anti-MRSA phages were sought in this study.

Methods: Of 437 S. aureus isolates, nine clinical MRSA isolates were obtained from three hospitals in Baghdad, Iraq and two ATCC MRSA strains were used to separate wild anti-MRS

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Publication Date
Thu Nov 14 2024
Journal Name
Journal Of Emergency Medicine, Trauma And Acute Care
Isolation, optimization, and redesigning of phages of methicillin-resistant Staphylococcus aureus from clinical hospital isolates in Baghdad
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Background: A global health concern is methicillin-resistant Staphylococcus aureus (MRSA). The use of bacteriophages is one of the many novel control strategies against MRSA that are frequently sought. However, it is quite challenging to isolate enough lytic anti-MRSA phages. In order to extract, optimize, and remodel anti-MRSA phages, this study sought novel approaches.

Methods: Two ATCC MRSA strains and nine clinical MRSA isolates were used to isolate wild anti-MRSA phages from hospital settings, dirt, and sewage. The wild phages were optimized using plaque-based biokinetic techniques. Usi

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Publication Date
Tue Sep 14 2021
Journal Name
Research Journal Of Pharmacy And Technology
The Isolation of specifically lytic phages along with their extracted endolysins as antibacterial agents to MDR Enterococcus faecalis
...Show More Authors

Background: Multidrug-resistant (MDR) enterococci have become a major problem in recent times and have been reported increasingly around the world. Lytic phages infect bacteria leading to rapid host death with limited risk of phage transduction, underlining the increasing interest in potential phage therapy in the future. Objective (s): The aim of this study is to use phage therapy as alternative approach for treatment of Enterococcus faecalis infections that recorded as MDR in Iraq to tackle this problem. Materials and Methods: Thirty E. faecalis isolates were collected from patients with different infectious diseases such as urinary tract infection (UTI), diabetic foot, septicemia, and wound infections. The isolation of specific l

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Publication Date
Sat Mar 21 2020
Journal Name
Electronic Journal Of General Medicine
The Possible Immunological Pathways for the Variable Immunopathogenesis of COVID—19 Infections among Healthy Adults, Elderly and Children
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Crossref (118)
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Publication Date
Thu Aug 13 2020
Journal Name
Asia Pacific Journal Of Molecular Biology And Biotechnology
The anticancer molecular mechanism of Carnosol in human cervical cancer cells: An in vitro study
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Carnosol, a phenolic diterpene, is one of the effective anticancer agents naturally occurring in rosemary, sage, parsley, and oregano. The chemoresistance problem increased with the routinely used chemotherapy. Therefore, the efforts to find a substitute with safe and low cost have become crucial worldwide. The current study attempts to inspect the anticancer molecular mechanisms of Carnosol on modulating up- and down- regulation of multiple genetic carcinogenesis pathways. The cytotoxicity of Carnosol on Hela cells was evaluated by MTS assay. Flow cytometry was used to assess apoptosis and cell cycle arrest. The apoptotic morphological changes were obvious by dual apoptosis assay. The differential gene expression after treatment wi

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Publication Date
Wed Apr 03 2024
Journal Name
Al- Anbar Medical Journal
Hypervirulent and the Multi-Drug Resistant Klebsiella oxytoca: A New Emerging Pathogen in Baghdad Hospitals, Iraq
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