Preferred Language
Articles
/
yBid6ZcBVTCNdQwCaKg8
Assessment of Six Polymorphic Variants as Genetic Risks for Coronary Artery Disease: A Case–Control Study
...Show More Authors
Abstract<sec> <title>Background:

Coronary artery disease (CAD) is the leading cause of death worldwide. Certain genetic polymorphisms play an important role in this multifactorial disease, being linked with increased risk of early onset CAD.

Objective:

To assess six genetic polymorphisms and clinical risk factors in relation to early onset nondiabetic Iraqi Arab CAD patients compared to controls.

Materials and Methods:

This case–control study recruited 40 Iraqi patients with early onset CAD and 20 healthy controls. Demographic and clinical data were reported. Six genetic variants were tested: β-fibrinogen (FGB), human platelet antigen 1 (HPA1a/b), angiotensin-converting enzyme (ACE), two variants of endothelial nitric oxide synthase (eNOS), and lymphotoxin alpha (LTA), utilizing a ready-to-use kit.

Results:

The majority of patients were older males (85%), nonsmokers (52.5%), hypertensives (57.5%), had dyslipidemia (100%), and had a family history of ischemia (77.5%). This contrasts the findings in the control group (P < 0.001). From the six studied polymorphisms, a statistically significant difference was found between patients and controls in relation to ACE and LTA genes (P = 0.032 and 0.028), respectively. None (0%) of the participants had a genetic risk score >6. There was a statistically significant association between higher clinical risk scores and CAD group; eNOS G894T was found to be linked with increasing age, while LTA was linked to dyslipidemia.

Conclusions:

This study aids in CAD risk stratification. There is a need for longitudinal studies assessing more genetic risks to CAD as a national CAD preventive program for high-risk Iraqi people.

Scopus Crossref
View Publication
Publication Date
Wed Aug 30 2023
Journal Name
Iraqi Journal Of Science
Periodontal Disease: A Predictive Profile
...Show More Authors

    Periodontal diseases such as gingivitis and periodontitis are considered common diseases. This study is aimed to predicate these diseases using non-harmful specimens such as saliva throughout the detection of some parameters. In the beginning, a random 51 patients' saliva was collected from outpatients who suffered from different degrees of periodontal diseases. Concurrently, another 40 people who appeared to be healthy were collected, and both patients and healthy people were subjected to a questionnaire form and diagnosed by a specialist dentist. The results of this study revealed that there is no significant difference between males and females in infection with periodontal diseases. As well, smoking is not acting as the m

... Show More
View Publication
Scopus Crossref
Publication Date
Sat Dec 24 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
A Comparative Study for the Accuracy of Three Molecular Docking Programs Using HIV-1 Protease Inhibitors as a Model
...Show More Authors

Flexible molecular docking is a computational method of structure-based drug design to evaluate binding interactions between receptor and ligand and identify the ligand conformation within the receptor pocket. Currently, various molecular docking programs are extensively applied; therefore, realizing accuracy and performance of the various docking programs could have a significant value. In this comparative study, the performance and accuracy of three widely used non-commercial docking software (AutoDock Vina, 1-Click Docking, and UCSF DOCK) was evaluated through investigations of the predicted binding affinity and binding conformation of the same set of small molecules (HIV-1 protease inhibitors) and a protein target HIV-1 protease enzy

... Show More
View Publication Preview PDF
Scopus (1)
Crossref (1)
Scopus Crossref
Publication Date
Mon Apr 05 2021
Journal Name
Solid State Technology
Genetic Algorithms in Construction Project Management: A Review
...Show More Authors

Genetic algorithms (GA) are a helpful instrument for planning and controlling the activities of a project. It is based on the technique of survival of the fittest and natural selection. GA has been used in different sectors of construction and building however that is rarely documented. This research aimed to examine the utilisation of genetic algorithms in construction project management. For this purpose, the research focused on the benefits and challenges of genetic algorithms, and the extent to which genetic algorithms is utilised in construction project management. Results showed that GA provides an ability of generating near optimal solutions which can be adopted to reduce complexity in project management and resolve difficult problem

... Show More
View Publication Preview PDF
Publication Date
Wed Aug 01 2018
Journal Name
Collegian
Behaviour change interventions to improve medication adherence in patients with cardiac disease: Protocol for a mixed methods study including a pilot randomised controlled trial
...Show More Authors

View Publication
Scopus (10)
Crossref (6)
Scopus Clarivate Crossref
Publication Date
Mon Feb 13 2023
Journal Name
International Journal Of Professional Business Review
The Reality of Local Investment in Iraq and Prospects for its Development: a Case Study in the Baghdad Investment Commission
...Show More Authors

Purpose: This research is to identify the most important challenges for the local investment commissions and to develop solutions and proposals to encourage local and foreign investment in local governments in Iraq (the Iraqi provinces are irregular in the region).   Theoretical Framework: This research suggests a conceptual framework for the local investment commissions in order to solve their problems, the most important of which was to identify the most critical challenges which are facing the Baghdad Investment Commission BIC and how to overcome them.   Design/The methodology approach: Research involved a mixed-methods approach through two stages. During the first stage, the researcher gathered quantitative data from all inves

... Show More
View Publication
Scopus Crossref
Publication Date
Fri Dec 23 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Descriptive, Prospective Observational Study- Studying Possible Prediction Factors for Disease Severity and Progression among a Sample of COVD 19 Patients in Iraq
...Show More Authors

Abstract

Coronavirus has affected many people around the world and caused an increase in the number of hospitalized patients and deaths. The prediction factor may help the physician to classify whether the patient needs more medical attention to decrease mortality and worsening of symptoms. We aimed to study the possible relationship between C reactive protein level and the severity of symptoms and its effect on the prognosis of the disease. And determine patients who require closer respiratory monitoring and more aggressive supportive therapies to avoid poor prognosis. The data was gathered using medical record data, the patient's medical history, and the onset of symptoms, as well as a blood sample to test the

... Show More
View Publication Preview PDF
Scopus (1)
Scopus Crossref
Publication Date
Tue Jan 01 2008
Journal Name
Journal Of Engineering
USING FUZZY LOGIC CONTROLLER FOR A TWO- TANK LEVEL CONTROL SYSTEM
...Show More Authors

This paper presents a fuzzy logic controller for a two-tank level control system, which is a process with a dead time. The fuzzy controller is a proportional-integral (PI-like) fuzzy controller which is suitable for steady state behavior of the system. Transient behavior of the system was improved without the need for a derivative action by suitable change in the rule base of the controller. Simulation results showed the step response of the two-tank level control system when this controller was used to control this plant and the effect of the dead time on the response of the system.

Publication Date
Wed Oct 25 2023
Journal Name
Urban Planning And Construction
A Review on Urban Planning and Its Role in Managing Flood Risks
...Show More Authors

This review delves deep into the intricate relationship between urban planning and flood risk management, tracing its historical trajectory and the evolution of methodologies over time. Traditionally, urban centers prioritized defensive measures, like dikes and levees, with an emphasis on immediate solutions over long-term resilience. These practices, though effective in the short term, often overlooked broader environmental implications and the necessity for holistic planning. However, as urban areas burgeoned and climate change introduced new challenges, there has been a marked shift in approach. Modern urban planning now emphasizes integrated blue-green infrastructure, aiming to harmonize human habitation with water cycles. Resil

... Show More
View Publication
Crossref (13)
Crossref
Publication Date
Thu Jan 20 2022
Journal Name
Webology
The Effect of Strategic Information System in Global Marketing Channel: A Case Study
...Show More Authors

The research dealt with the issue of strategic information systems and its impact on the global marketing channel. As the research aims to know the strategic information systems used in the cement company. Which support the senior management in supporting decisions taken in the process of global orientation and moving to foreign markets by choosing the marketing channel that will suit the company. Product and competition with it. With other companies' products. The problem of the study focused on how to move to global markets, and any marketing channel that can be followed to move the cement product globally, what are the strategic information systems used in the company and how will it contribute to supporting senior management dec

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sun Oct 01 2023
Journal Name
Nasq
The Impact of Harold Pinter’s Drama Upon the Iraqi Theatre: A Case Study
...Show More Authors

THE IMPACT OF BRITISH THEATER UPON IRAQI DRAMA