The presented study investigated the scheduling regarding jobs on a single machine. Each job will be processed with no interruptions and becomes available for the processing at time 0. The aim is finding a processing order with regard to jobs, minimizing total completion time , total late work , and maximal tardiness which is an NP-hard problem. In the theoretical part of the present work, the mathematical formula for the examined problem will be presented, and a sub-problem of the original problem of minimizing the multi-objective functions is introduced. Also, then the importance regarding the dominance rule (DR) that could be applied to the problem to improve good solutions will be shown. While in the practical part, two exact methods are important; a Branch and Bound algorithm (BAB) and a complete enumeration (CEM) method are applied to solve the three proposed MSP criteria by finding a set of efficient solutions. The experimental results showed that CEM can solve problems for up to jobs. Two approaches of the BAB method were applied: the first approach was BAB without dominance rule (DR), and the BAB method used dominance rules to reduce the number of sequences that need to be considered. Also, this method can solve problems for up to , and the second approach BAB with dominance rule (DR), can solve problems for up to jobs in a reasonable time to find efficient solutions to this problem. In addition, to find good approximate solutions, two heuristic methods for solving the problem are proposed, the first heuristic method can solve up to jobs, while the second heuristic method can solve up to jobs. Practical experiments prove the good performance regarding the two suggested approaches for the original problem. While for a sub-problem the experimental results showed that CEM can solve problems for up to jobs, the BAB without dominance rule (DR) can solve problems for up to , and the second approach BAB with dominance rule (DR), can solve problems for up to jobs in a reasonable time to find efficient solutions to this problem. Finally, the heuristic method can solve up to jobs. Arithmetic results are calculated by coding (programming) algorithms using (MATLAB 2019a)
Cytokines are a group of immunomodulatory proteins leading to a variety of immune reactions in the human; these cytokines play a significant role in the development of appropriate immune responses against T. gondii. This study aims to reveal the association of toxoplasmosis with serum levels of IL-3, IL-17A, and IL-27 in aborted women. The blood samples of patients and controls were collected from Al-Alawiya Maternity Teaching Hospital/Baghdad/Iraq from 2019 to 2020 for detecting anti-T. gondii antibodies (IgG and IgM) and the level of interleukins by ELISA. The results of TORCH by rapid test for recurrent abortion recorded 25.3% seropositive for anti-Toxoplasma antibodies, and 31.5% seropositive for one or more cases of TORCH test (Cytomeg
... Show MoreCurcumin (Cur) possesses remarkable pharmacological properties, including cardioprotective, neuroprotective, antimicrobial, and anticancer activities. However, the utilization of Cur in pharmaceuticals faces constraints owing to its inadequate water solubility and limited bioavailability. To overcome these hurdles, there has been notable focus on exploring innovative formulations, with nanobiotechnology emerging as a promising avenue to enhance the therapeutic effectiveness of these complex compounds. We report a novel safe, effective method for improving the incorporation of anticancer curcumin to induce apoptosis by reducing the expression levels of miR20a and miR21. The established