Higher education is one of the foundational pillars that contributes to the development of societies and the achievement of social and economic progress. With the accelerating advancements in technological, environmental, and social fields, universities and educational institutions worldwide are facing significant challenges requiring them to adapt to these changes and develop new educational strategies. In this context, directing higher education towards achieving sustainable development goals (SDGs) has become imperative, as these goals are now an integral part of modern societies' vision, particularly in light of global challenges such as climate change, population growth, and unemployment. By the year 2050, educational institutions are expected to undergo fundamental transformations in the way education is delivered, necessitating innovative and advanced models that align with technological changes and meet the needs of the future labor market. This research focuses on anticipated changes in higher education based on five core axes for its development towards a sustainable future: Students: Emphasizing the enhancement of their digital skills and fostering critical and creative thinking abilities in learn. Instructors: Facing new challenges that require adaptation to modern technologies and the development of teaching methods suited to students' needs. Curriculums: Incorporating concepts of innovation and sustainability, with a focus on developing problem-solving skills for students. Infrastructure: Significant transformations turning universities into smart educational hubs that support remote and blended learning while ensuring campus sustainability. Administrative Bodies: Developing strategies capable of adapting to rapid changes and ensuring effective coordination among stakeholders, including governments and Various institutions Through these axes, this research aims to foresight the future of higher education by 2050 and explore how it can adapt to future challenges while achieving sustainable development goals.