خلفية البحث: مرض السكري هو عامل خطر لأمراض القلب والأوعية الدموية وتصلب الشرايين وسبب مهم للوفاة. يرتبط خلل الدهون في الدم بشكل شائع بمرض السكري من النوع الثاني ويعتبر مؤشر تصلب الشرايين في البلازما علامة قوية للتنبؤ بخطر الإصابة بتصلب الشرايين وأمراض القلب التاجية. الهدف من البحث: دراسة ارتباط المؤشرات الدهنية لتصلب الشرايين لدى المرضى العراقيين المصابين بالسكري من النوع الثاني ولديهم أمراض قلبية وعائية. المرضى وطرق العمل: أجريت هذه الدراسة السريرية في مستشفى بغداد التعليمي/ مدينة الطب - بغداد في الفترة من تشرين الأول 2022 ولغاية شباط 2023. تم مشاركة 60 مريضًا مصاباً بالسكري من النوع الثاني في هذه الدراسة. ثلاثون مريضا منهم كانوا يعانون من أمراض القلب والأوعية الدموية و 30 غير مصابين بأمراض القلب والأوعية الدموية. تراوحت أعمارهم بين 40-55 سنة. تم اختيار 30 فردًا سليما كمجموعة سيطرة. النتائج: كان هناك ارتفاع كبير في فحوصات نسبة السكر والدهون في الدم لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية مقارنة مع أولئك الذين لا يعانون من أمراض القلب والأوعية الدموية ومجموعة السيطرة. أظهرت النتائج الحالية مستويات مرتفعة من نسب الدهون لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية. كشفت النتائج أيضًا عن مستويات عالية من البروتين الدهني غير عالي الكثافة لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية (241.8 ± 12.24 ملغم/ ديسيلتر) مقابل (150.1 ± 7.12 و 68.9 ± 5.1 ملغم/ ديسيلتر) لأولئك الذين لا يعانون من أمراض القلب والأوعية الدموية ومجموعة السيطرة على التوالي. كان مؤشر تصلب الشرايين للبلازما لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية مقارنة بمجاميع مرضى السكري والأصحاء (0.8 ± 0.09) مقابل (0.7 ± 0.03 و 0.2 ± 0.08) على التوالي. كان هناك ارتباط معنوي موجب بين مؤشر تصلب الشرايين للبلازما والعوامل الجسمية، صورة السكر والدهون في الدم مع نسبها لدى مرضى السكري مع وبدون أمراض القلب والأوعية الدموية. الاستنتاجات: تؤكد نتائج هذه الدراسة أن مؤشرات الدهون هي مؤشرات خطر لضبط نسبة السكر في الدم بقيمة تنبؤية أعلى من العوامل التقليدية. أيضًا، ممكن اعتبار البروتين الدهني غير عالي الكثافة ومؤشر تصلب الشرايين في البلازما من العوامل الهامة للسيطرة على نسبة السكر في الدم.
Azo derivative ligand[H3L] have been synthesized by the reaction of diazonium salt of p-amino benzoic acid with orcinol in(1:1)mole ratio. The bidente ligand was reacted with the metal ions MnII,FeIIandCrIIIin(2:1)mole ratio via reflux in ethanol using Et3N as a base to give complexes of the general formula: [ M(H2L)2(H2O)x]Cly The synthesized compounds were characterized by spectroscopic methods[ I.R , UV-Vis, A.A and H1 NMR]along with melting point, chloride content and conductivity measurements. The complexes were screend for their in vitro antibacterial activity against one strain of staphylococcus as Gram(+) positive and one strain of pseudomonas as Gram(-) Negative, using the agar diffusion technique.
The health care industry is witnessing an increasing trend in the use of generic medicines because of their presumed low cost compared with innovator medicines. The aim of this study was to determine and compare the performance of the copy drug Osveral®and its innovator drug deferasirox (Exjade®).
A prospective observational study including 223 patients receiving the branded medicine Exjade®and 101 patients receiving the copy Osveral®was carried out. Data were assessed for a 1-year period and included clinical symptoms, serum ferrit
The objectives of this research are to determine and find out the reality of crops structure of greenhouses in association of Al-Watan in order to stand on the optimal use of economic resources available for the purpose of reaching a crop structure optimization of the farm that achieves maximize profit and gross and net farm incomes , using the method of linear programming to choose the farm optimal plan with the highest net income , as well as identifying production plans farm efficient with (income - deviation) optimal (E-A) of the Association and derived, which takes into account the margin risk wich derived from each plan using the model( MOTAD), as a model of models of linear programming alternative programming m
... Show MoreColorectal cancer (CRC), the second most fatal cancer and the 3rd most common cancer is expected to cause 0.9 million deaths globally in 2025. Carcinoembryonic antigen (CEA) is currently used in the follow-up of patients with colorectal cancer, and in this study, we are trying to find a better marker than CEA in following up on patients' health and knowing the effectiveness of the treatment used and as a diagnostic marker for colorectal cancer. To determine the significance of Cancer antigen 72-4 (CA72-4) as a prognosis predictor in patients with colorectal cancer, compare its prognostic validity to the CEA biomarker. this case-control study includes (150) participants, 100 patients (59 males and 41 females), and 50 healthy controls
... Show MoreDiabetes mellitus is a set of metabolic diseases, the most prevalent of which is chronic hyperglycemia. The culprits include insulin synthesis, insulin action, or both. Osteoporosis is a progressive systemic skeletal disorder defined by decreased bone mass and micro architectural degeneration of bone tissue, resulting in increased bone fragility and fracture risk, according to the World Health Organization (WHO). The degree of Nervosa damage determines how much a diabetic patient's body has been compromised. The current study's goal is an estimation: Age, BMI, FBS, HbA1C, D3, ALP, Ca, P, and Osteocalcin in Iraqi T2DM Women's patients with and without Osteoporosis. Three vitamins are required for Osteocalcin biosynthesis: vitamin K for Gla f
... Show More60 patients diagnosed as having urticaria were included in the study ; 30 patients were effected with acute urticaria and 30 patients were affected with chronic urticaria. In addition, 30 healthy adult volunteers were selected as control group .The patients and control groups sera were examined with enzyme linked immunosorbent assay ( ELISA) to detect total level IgE and radial immunodiffusion (RID) to detect levels of IgG , IgA and IgM . The total level of IgE in acute urticaria ( 1.45±0.13) IU/mL and chronic urticaria (2.12 ± 0.10) IU/mL patients were significantly higher than the control groups ( 0.85 ± 0.10)IU/mL (p<0.05). The level of IgG in acute urticaria ( 12.5± 0.42) g/L and chronic (13.16±0.40) g/L patients , IgA in acute (2.
... Show MoreBackground: EOS (encoded by the IKZF4 gene) is a member of the zinc finger transcription factor IKaros family, and plays a critical role in Treg suppressor functions, and maintaining Treg stability. IL-6 is a soluble mediator with a pleiotropic effect on inflammation, immune response, and hematopoiesis. Aim: To estimate serum IL-6 level and EOS gene expression in Iraqi patients with psoriasis. Method: Twenty-two patients with psoriasis (8 females, 14 males) with age ranged 18-72 years, were recruited from Baghdad Teaching Hospital, Dermatology Clinic, Baghdad, and 24 healthy donors. The serum levels of IL-6 by ELISA and the gene expression of IKZF4 (EOS gene) by RT-qPCR technique. Results: The results showed a non-significant diffe
... Show MoreHepatitis B virus (HBV) infection is a serious disease of the liver and signifies a major worldwide health concern. HBV Genotyping is vital for further epidemiological study, predicting the disease outcome and response to treatment. The current study aimed to determine hepatitis B virus genotypes in patients with chronic hepatitis B, and to validate possible associations with the baseline characteristics of the disease. A total of 90 patients with chronic hepatitis B infection were enrolled in this study. Liver function tests, hepatitis B virus markers and DNA viral load were done using routine standardized procedures. HBV genotyping was performed using real time PCR. Genotype D was the most predominant in 64 (71.1%) of samples, while
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