خلفية البحث: مرض السكري هو عامل خطر لأمراض القلب والأوعية الدموية وتصلب الشرايين وسبب مهم للوفاة. يرتبط خلل الدهون في الدم بشكل شائع بمرض السكري من النوع الثاني ويعتبر مؤشر تصلب الشرايين في البلازما علامة قوية للتنبؤ بخطر الإصابة بتصلب الشرايين وأمراض القلب التاجية. الهدف من البحث: دراسة ارتباط المؤشرات الدهنية لتصلب الشرايين لدى المرضى العراقيين المصابين بالسكري من النوع الثاني ولديهم أمراض قلبية وعائية. المرضى وطرق العمل: أجريت هذه الدراسة السريرية في مستشفى بغداد التعليمي/ مدينة الطب - بغداد في الفترة من تشرين الأول 2022 ولغاية شباط 2023. تم مشاركة 60 مريضًا مصاباً بالسكري من النوع الثاني في هذه الدراسة. ثلاثون مريضا منهم كانوا يعانون من أمراض القلب والأوعية الدموية و 30 غير مصابين بأمراض القلب والأوعية الدموية. تراوحت أعمارهم بين 40-55 سنة. تم اختيار 30 فردًا سليما كمجموعة سيطرة. النتائج: كان هناك ارتفاع كبير في فحوصات نسبة السكر والدهون في الدم لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية مقارنة مع أولئك الذين لا يعانون من أمراض القلب والأوعية الدموية ومجموعة السيطرة. أظهرت النتائج الحالية مستويات مرتفعة من نسب الدهون لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية. كشفت النتائج أيضًا عن مستويات عالية من البروتين الدهني غير عالي الكثافة لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية (241.8 ± 12.24 ملغم/ ديسيلتر) مقابل (150.1 ± 7.12 و 68.9 ± 5.1 ملغم/ ديسيلتر) لأولئك الذين لا يعانون من أمراض القلب والأوعية الدموية ومجموعة السيطرة على التوالي. كان مؤشر تصلب الشرايين للبلازما لدى مرضى السكري المصابين بأمراض القلب والأوعية الدموية مقارنة بمجاميع مرضى السكري والأصحاء (0.8 ± 0.09) مقابل (0.7 ± 0.03 و 0.2 ± 0.08) على التوالي. كان هناك ارتباط معنوي موجب بين مؤشر تصلب الشرايين للبلازما والعوامل الجسمية، صورة السكر والدهون في الدم مع نسبها لدى مرضى السكري مع وبدون أمراض القلب والأوعية الدموية. الاستنتاجات: تؤكد نتائج هذه الدراسة أن مؤشرات الدهون هي مؤشرات خطر لضبط نسبة السكر في الدم بقيمة تنبؤية أعلى من العوامل التقليدية. أيضًا، ممكن اعتبار البروتين الدهني غير عالي الكثافة ومؤشر تصلب الشرايين في البلازما من العوامل الهامة للسيطرة على نسبة السكر في الدم.
The infection with H. Pylori stimulates a signaling cascade that causes the generation of Cytokines and provokes Oxidative stress that is involved in the chronic inflammatory response leads to Gastric cancers. Reactive oxygen species (ROS) produce 8-Hydroxydeoxyguanosine (8-OHdG), the persistent oxidative DNA damage product. The study objective was to assess if there was a link between inflammatory cytokine levels and the presence of Oxidative DNA damage in Gastric tumor patients. In addition, evaluation of the diagnostic and prognostic value of Oxidative DNA damage and inflammatory cytokine biomarkers for Stomach cancers is being conducted. The study was accomplished on medically diagnosed Stomach cancer patients before any form of trea
... Show MoreBackground: Recent studies suggest that chronic periodontitis (CP) and type2 diabetes mellitus (T2DM) are bidirectionally associated. Analysis of saliva as a mirror of oral and systemic health could allow identification of α amylase (α-Am) and albumin (A1) antioxidant system markers to assist in the diagnosis and monitoring of both diseases. The present study aims at comparing the clinical periodontal parameters in chronic periodontitis patients with poorly or well controlled Type 2Diabetes Mellitus, salivary α-Am, A1, flow rate (FR) and pH then correlate between biochemical, physical and clinical periodontal parameters of each study and control groups. Materials and Methods: 80 males, with an age range of (35-50) years were divide
... Show MoreThis study was conducted to detect the relationship between organic content in the sediment of Rivers Tigris and Diyala, at two locations south of Baghdad, with some environmental factors and the benthic invertebrates and values of diversity indices. Monthly samples collected from the area for the period November 2007 to October 2008. Results showed differences in the physical and chemical characteristics of the two sites, Where the annual average in Tigris and Diyala were respectively for: water temperature (19, 20) C°, pH (8, 8), dissolved oxygen (4, 8) mg / l , Biochemical oxygen Demand BOD5 (3,44 ) mg/l, TDS (632,1585) mg / l, TSS (42, 44) mg / l, turbidity (28,74) NTU, and total hardness as CaCO3 (485,823) mg / l ,Sulfat
... Show MoreTrigeminal Neuralgia (TN) is one of the most commonly painful cranial neuralgia characterized by paroxysmal attacks as short lasting facial pain along the trigeminal nerve branches. The aim of the present study is to innovate a biochemical relationship between (melatonin, GALNT12 and Zn) and TN and also to examine the biochemical action of tegretol (carbamazepine) as a treatment on the above biochemical parameters. Blood samples were collected from fifty four (54) trigeminal neuralgia patients diagnosed by magnetic radiation image (MRI). Patients were classified into four groups: G3 (40- 70) years composed of (12) diagnosed male (without treatment), G4 (48- 75) years composed of (12) diagnosed female (without treatment), G5 (34- 76)
... Show MoreInfection of the gastric mucosa with Helicobacter pylori is strongly associated with chronic gastritis, peptic ulcer and gastric cancer. Helicobacter pylori virulence factors include a variety of proteins that are involved in its pathogenesis, such as VacA and CagA. Another group of virulence factors is clearly important for colonization of H.pylori in the gastric mucosa. These include urease, motility factors (flagellin), and Superoxide dismutase (SOD). Because of this organism's microaerophilic nature and the increased levels of reactive oxygen in the infected host, we expect that other factors involved in the response to oxidative stress are likely to be required for virulence. Superoxide dismutase is a near
... Show MoreBackground: The present study involved the following parts, the first part is evaluation of the levels of glycated hemoglobin(HbA1c), creatinine, uric acid(UA) and albumin in patients with diabetic nephropathy comparison with the group of healthy as a control group. The second part is the measurement and evaluation of oxidative stress represented in the malondihydehyde(MDA) as a biomarker of oxidative stress as well as the identification of vitamins C and E as an antioxidant in patients with diabetic nephropathy(DN) compared with the healthy group. Objective: The objective of this study is to estimate oxidative stress by calculate malondialdehyd as biomarker and evaluate some vitamins such as vit C and vit E as antioxidants in diabetic neph
... Show MoreBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is still a severe threaft for human health currently, and the researches about it is a focus topic worldwide.
Aim of the study: In this study, we will collect some laboratory results of the patients with coronavirus disease (COVID-19) to assess the function of liver, heart, kidney and even pancreas.
Subjects and Methods: Laboratory results of the patients with COVID-19 are collected. The biochemical indices are classified and used to assess the according function of liver, heart, kidney; meantime, and blood glucose is also observed and taken as an index to roughly evaluate pancreas.
Results: There were some in
... Show MoreThis study included estimation of glutathione (GSH) and Malondialdehyde (MDA) levels in the serum of diabetic patients type II who are treated with a polyherbs mixture (Nigella sativa, Trigonella foenum-graeum, Cyperus rotundus and Teucrium polium) for three months of treatments. Seventy samples of diabetic patients Type II male and females with age about (35-60) years were taken including 44 samples for group one (24 male, 20 female) who used herbs accompanied with chemical treatment (drugs) and 26 samples for the second group (13male and 13 female) who used herbs only. These groups were compared with 60 samples obtained from healthy persons (29 male, 31 female) at the same age of patients as a control group. Effect of age and treatment fo
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