Discrete Racah polynomials (DRPs) are considered essential for several applications such as approximation theory, quantum physics, and digital signal processing. However, the computation of high-order DRPs presents significant numerical and computational challenges. Even though the recent advancements in algorithms have improved numerical stability, the inherently sequential nature of these algorithms continues to be a bottleneck for large-scale implementations. This paper proposes a new multithreading-based algorithm for computing the DRP coefficients. The proposed algorithm is designed to accelerate the computation of high-order DRPs by considering the advantages of the independence of different tasks and the ability to process multiple coefficients simultaneously. The algorithm introduces distinct multithreading strategies for both zero-valued and non-zero-valued parameters, which include the zero-parameter balanced algorithm (ZPBA), the zero-parameter unbalanced algorithm (ZPUA), and the valued-parameter algorithm (VPA). The experimental results show that the proposed multithreading algorithms noticeably reduce computation time when compared to the state-of-the-art baseline algorithm. Notably, both ZPBA and VPA exhibit exceptional scalability across modern multicore architectures, delivering speedup factors exceeding 10× for large polynomial sizes. This work effectively bridges the gap between mathematical theory and high-performance computing, making the generation of large-scale DRP matrices computationally viable for advanced engineering applications.
Natural honey is well known for its therapeutic value and has been used in traditional medicine of different cultures throughout the world. The aim of this study was to investigate the anti-inflammatory effect of Malaysian Gelam honey in inflammation-induced rats. Paw edema was induced by a subplantar injection of 1% carrageenan into the rat right hind paw. Rats were treated with the nonsteroidal anti-inflammatory drug (NSAID) Indomethacin (10 mg/kg, p.o.) or Gelam honey at different doses (1 or 2 g/kg, p.o.). The increase in footpad thickness was considered to be edema, which was measured using a dial caliper. Plasma and paw tissue were collected to analyze the production of inflammatory mediators, such as NO, PGE2
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