استشعار النصاب (Quorum sensing, QS) هو آلية معروفة تستخدمها جراثيم عديدة للسيطرة على عوامل الضراوة الهامة من خلال الإنتاج والاستجابة اللاحقة ل .)N-acylhomoserine (AHLs جرى تسجيل تثبيط استشعار النصاب (QSI) ، الذي يستهدف الإشارات المعتمدة على AHL، كاستراتيجية للسيطرة على الأمراضية الجرثومية. وبالتالي، تهدف هذه الدراسة إلى البحث عن قدرة جرثومة الزائفة الزنجارية كمؤشر للفحص السريع عن QSI المحتمل المتسبب عن المستخلصات النباتية على أساس تثبيط الصبغة. استخدمت أربع مستخلصات نباتية كحولية بضمنها: براعم زهور القرنفل المجففة ( Syzygium aromaticum L)، لحاء القرفة (Cinnamomum cassia L)، أوراق المورينجا (Moringa oleifera Lam)، والقطب (Tribulus terrestris L) وجرى مقارنة قابيلتها على التثبيط QSI)) مع الفيورانون. استخدمت طريقة الانتشار في حفر الهلام، إذ جري تلقيح عزلة الزائفة الزنجارية على وسط الهلام الخاص بـها الذي احتوى على حفر بحجم 8 ملم لتحميل تراكيز مختلفة من المستخلصات النباتية فضلا عن الفيورانون أو محلول الفوسفات الداريء (سيطرة سالبة). أظهرت النتائج نجاح الفيورانون في تثبيط صبغة البايوسيانين للزوائف الزنجارية دون التداخل مع النمو الجرثومي، وهذا يؤكد قدرة هذه العزلة الجرثومية كمؤشر فعال يستدل من خلاله على وجود QS. الأهم من ذلك، سبب مستخلص القرنفل بتراكيز مختلفة في تثبيط تام لصبغة البايوسيانين مع تأثير ضئيل على النمو الجرثومي. عند استخدام القرفة، أظهرت التراكيز العالية فقط تثبي ًطا واض ًحا لصبغة العزلة المستخدمة. تسببت المورينغا أي ًضا في درجة معينة من تثبيط الصبغة ولكن بتراكيز عالية فقط. وعلى العكس من ذلك، لم يؤثر القطب على إنتاج البيوسيانين ولا على الحيوية الجرثومية. يستنتج من هذه الدراسة نجاح عزلة الزائفة الزنجارية المنتجة للبايوسيانين في فحص مثبطات QS. توصي هذه الدراسة البسيطة باستخدام مثل هذه العزلة ككاشف عن QSI دون الاعتماد على استيراد سلالات معينة من جراثيم Chromobacterium violaceum أو Pseudomonas aureofaciens أو Agrobacterium tumefaciens.
The audit profession today gets an increasing interest by the financial , economic and legal contemporary societies , because of the importance of the technical & neutral auditor’s opinion to the financial reports beneficiaries in order to enable them making their investment decisions , but some of them whom suffered damage or loss when they made that decisions according to the mentioned financial statements which consolidated with auditor’s report , exposed the function to a responsibility and credibility crisis in addition to missing the trust especially at the latest years. They always ask why or what is the reason that cause the auditor didn’t giving us any warning signs about the economic mater for that companies.
The economic units always sought to maintain its market position and Trchinh the technology management and modern methods that will support success factors .vdila about it has become a customer and one profitability analysis of the most practical way benefit of economic units as modern management focus their attention on achieving this satisfaction, as the customers make up the axis of the success of every organization and that there are many government units aiming to profit directs attention to customers and the number of these units increased continuously. The administration used the customer profitability analysis in order to obtain information to assist in making and decision-making process. How to use modern tec
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his project try to explain the using ability of spatial techniques for land cover change detection on regional level with the time parameter and did select for explain these abilities study case (Hewaizah marsh ) . this area apply to many big changes with the time. These changes made action on characters and behaviors of this area as well as all activities in it . This Project concerting to recognize the Using importance of remote sensing and GIS Methodology in data collecting for the changes of land use and the methodology for the analyses and getting the results for the next using as a base data for development and drawing the plans as well as in regional planning .This project focus on practical
... Show MoreKlebsiella pneumoniae has been found in the urinary tract of some bladder cancer patients. Bacterial presence within tumor tissue may affect the tumor-microenvironment and consequently influence cancer behavior, development, and treatment response. This study investigated mesenchymal and stemness transdifferentiation of bladder cancer cell line due to environmental stress of K. pneumoniae. Cultures of urothelial bladder cancer cell line (T24) were infected with K. pneumoniae with different multiplicity of infection (MOI) for two and four days. Transdifferentiation-associated features were morphologically assessed.
Moreover, transdifferentiation markers were estimated using Q-PCR and immunohistoc
... Show Moreلقد إزدادت التطورات العلمية والتكنولوجية ولاسيما المعلوماتية زيادة في العلوم والحقائق والنظريات والإكتشافات بصورة مذهلة، وكذلك زيادة فروع في العلم والمعرفة ففي كل يوم نشهد قيام فروع أو تخصص معرفي جديد، إضافة إلى تفجر المعرفة التي ساهمت في بناء قنوات الفروع والتخصصات العلمية القديمة والجديدة (عبد الغفور 2001 ص8).
فالثورة في مجال العلم والمعرفة والمعلومات والإتصا
... Show MoreThis study deals with examining UCAS students’ attitudes in Gaza towards learning Arabic grammar online during the Corona pandemic. The researcher has adopted a descriptive approach and used a questionnaire as a tool for data collection. The results of the study have statistically shown significant differences at the level of "0.01" between the average scores of students in favor of the students of the humanities specializations. It has also been found that the students’ attitudes at the Department of Humanities and Media towards learning Arabic grammar online are positive. Additionally, the results revealed no statistical significant differences due to the variable of UCAS students’ scientific qualifications. The results stressed
... Show MoreThe current research aims to shed light on the Global Reporting Initiative (GRI), which helps to report financial and non-financial information by economic units in general and listed on the Iraq Stock Exchange in particular. The research was based on a main premise that apply the criteria of the Global Reporting Initiative (GRI) would provide useful information to users to help them make appropriate decisions. To achieve the goal of the research, the descriptive analysis method was used, and quantitative analysis was used. At the level of the descriptive analysis method, a desk survey was conducted. As for the quantitative analysis, it relied on applied data through a questionnaire form (Questioners) as a research tool, and the
... Show MoreThis research deals with the role of quantitative (indirect) tools of monetary policy that used by the Central Bank of Iraq in order to control and manage the size of the money supply that intermediate goal through which monetary policy is able to achieve its final goals, foremost among which is to reduce inflation and raise the value of the local currency in front of foreign currency rates. The research is based on a major hypothesis stating that quantitative tools have a direct and strong influence on the money supply, especially under the circumstances of the shift towards a market economy. There has been a branching relationship with this statistically significant relationship between the money supply and the quantitative tools used
... Show MoreOrganophosphorus insecticide and growth regulator namely Ethephon (2-chloroethylphosphonic acid) are widely used as a ripening process accelerator and a cultivation duration inhibitor. Pomegranate extract (PPE) has recently been taken into consideration due to its pharmacological effects especially those associated with renal diseases. Thus, this study aims to investigate the possible protective effect of PPE against ethephon-induced nephrotoxicity in rats. In this study four groups of adult male rats were divided into control group, PPE 400 mg/kg group, Ethephon 250 mg/kg group, and finally, PPE + Ethephon group (treated with the same dose of PPE group and Ethephon group). In the current study, kidney function parameters (KIM-1, creatin
... Show MoreSamuel Beckett’s Happy Days (1961) clearly portrays a lack of communication among the characters of the play which refers to the condition of modern man. This failure of communication led Samuel Beckett to use a lot of pauses and silences in all plays written instead of using words. To express the bewilderment of the modern man during the 20th century, Beckett adopts the use of no language strategy in the dramatic works. After World War II, people were without hope, religion, food, jobs, homes, or even countries. Beckett gave them a voice. He used a dramatic language out of everyday things, in which silence was part of the syntax as a poetic repetition. Language is no more important to the modern man; instead, he us
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