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The Frequency and Spectrum of K-ras Mutations among Iraqi Patients with Sporadic Colorectal Carcinoma (CRC)
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BACKGROUND: CRC is one of the most common cancers in the world. K-ras is proto-oncogene with GTPase activity that is lost when the gene is mutated. Analysis of K-ras mutational status is very important for CRC treatment, being the most important predictors of resistance to targeted therapy. OBJECTIVE: This study aims to determine the frequency and spectrum of K-ras mutation among Iraqi patients with sporadic CRC. PATIENTS, MATERIALS AND METHODS: This study enrolled 35 cases with sporadic CRC; their clinicopathological parameters were analyzed. The FFPE blocks were used for DNA extraction; PCR amplification of K-ras gene and hybridization of allele-specific oligoprobes were performed. The assay covers 29 mutations in the K-ras gene (codons 12, 13, 59, 60, 61, 117 and 146). RESULTS: The majority of cases have left colonic tumours (57%), without LN involvement (57.1%), of non-mucinous adenocarcinoma histology (85.7%), grade II (82.9%) and stage III (37.1%) tumours. Fourteen mutations were detected in 13 (37%) patients with K-ras mutations; 10 (71.4%) mutations were in codon 12 while 4(28.6%) were in codon 13. The most frequent mutation was the G>T transversions [9 (64.4%)] and the most frequent mutation type was GGT>TGT (GLY>CYS) at codon 12. CONCLUSION: The incidence of K-ras mutations lies in the middle of the reported figures worldwide; the majority of mutations occurred at codon 12 followed by codon 13; predominantly of G>T transversion and Gly12Cys type that has a poorer prognosis.

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Publication Date
Sun Oct 01 2017
Journal Name
Journal Of Educational And Psychological Researches
Cyber bullying among college students
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The current research aimed to explore the practicing of cyber bullying among college students as well as the differences of practicing cyber bullying among university students based on gender variable. The finding revealed that there was a high prevalence rate for cyber bullying among research sample who was students from Baghdad University. It assured clearly that this group participated in cyber bullying effectively, due to the biological and psychological factors which make them super sensitive toward the social and economic problems. Moreover, the results showed that there were significant differences between male and female in practicing cyber bullying. The study proved that women use cyber bulling more than men.  

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Publication Date
Wed Oct 18 2023
Journal Name
Iraqi National Journal Of Nursing Specialties
Job Satisfaction among Nursing Staff
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Objectives: The specific objectives of the present study were to assess the level of job satisfaction among
nursing staff who are working in the Ministry of Health and Ministry of Higher Education and Scientific
Research in the provinces of Erbil, Mosul and Kirkuk to determine the factors that affect their satisfaction.
Methodology:٨
descriptive design was carried-out from September 20, 2006 through April 1,'؛ 2007 in order
to assess the job satisfaction for nursing staff in governmental health agencies and educational setting.
Quantitative research methods were utilized to employ the study design. The study was conducted on three Iraqi
governorates (Mosul, Kirkuk, and Erbil). The sample of the study was collected

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Publication Date
Tue Jan 02 2018
Journal Name
Journal Of Educational And Psychological Researches
Masculine identification among secondary schoolboys
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The purposes of this study are to measure masculine's identification among secondary school students, and to examine the significant differences among secondary school students in respect of students age (16-18) year. The researcher has prepared a questionnaire comprised (25) item to measure masculine identification among students: this scale was applied on (100) student who were selected as a sample from four different school at al-rusafa side in Baghdad. The scale then modified to (23) item to be more consistent. The results revealed that there were no significant differences among students based on the variable of age, and the mean of masculine identification showed a high level than the hypothesized mean.

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Publication Date
Tue Jan 02 2018
Journal Name
Journal Of Educational And Psychological Researches
Voluntary work among university students
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This research aims to identify the level of Voluntary work among university students, and explore the statistical differences of voluntary work among students due the gender and major. A total of (400) male and female student from morning study were selected as a sample to achieve the research's objectives. Al-Malaki (2010) scale was adopted to collect the required data. The results revealed that men take massive part in voluntary work than women, and students of human sciences showed significant differences than those of other majors.   

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Publication Date
Sun Apr 03 2016
Journal Name
Journal Of Educational And Psychological Researches
KINDNESS AMONG FEMALE UNIVERSITY STUDENTS
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The research aims at constructing a Scale of Kindness phenomenon among university female students and elicit criteria to it, It also recognizes the differences in kindness levels among female students according to variables (specialization, academic grade, social status, and the age). The sample consists of 534 female students who were selected randomly. The two researchers rely on experience and the results of questionnaire, The questionnaire is given to 130 female university students from different colleges as well as their acquaintance with literary works witch dealt with kindness , The scale consists of 39 items , It has psychometric characteristics (Validity and Reliability) . The criterion (Z) is extracted from it and throu

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Publication Date
Wed Jun 07 2023
Journal Name
Journal Of Educational And Psychological Researches
Mental Fatigue among University Teachers
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The current research aims to measure the level of mental fatigue among the teachers of the University of Baghdad, as well as to measure the significant differences according to the variable of mental fatigue in terms of male and female teachers, specialization (humanitarian, scientific), and title (professor, assistant professor, lecturer). To achieve these current goals, a random sample of (300) teachers from University of Baghdad was selected for the academic year 2019-2020. To measure the mental fatigue, the researcher developed a tool to measure the variable included (56) items. The research revealed that the study sample is mentally tired, the female sample is more mentally tired than males, there are no statistically significant di

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Publication Date
Wed Mar 23 2022
Journal Name
Journal Of Educational And Psychological Researches
Introspective Awareness among College Students
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The current study aims to identify the introspective awareness of the study sample, as well as to identify the introspective awareness of the study sample in terms of gender. The researcher adopted the viewpoint of Mehling (2002) as a theoretical framework for Introspective awareness. A sample of (239) male students and (331) female students were chosen randomly from two universities (Baghdad University and Al- Mustansiriyah University). To achieve the objectives of the research, the researcher adopted a vulgar scale (Mehling, 2012), which in its final form consisted of (32) items distributed into eight domains. As for the reliability coefficient of the scale, it reached (0.896) in the Cronbach alpha equation. The study revealed that the

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Publication Date
Wed Dec 01 2021
Journal Name
Gene Reports
The molecular study for evaluation the antibiotic resistance of Escherichia coli and Klebsiella pneumoniae bacteria isolated from urinary tract infection patients
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Urinary tract infection is a bacterial infection that often affects the bladder and thus the urinary system. E. coli is one of the leading uropathogenic bacteria that cause urinary tract infections. Uropathogenic E. coli is highly effective and successful in causing urinary tract infections through biofilm formation and urothelial cell invasion mechanisms. Other organisms that cause urinary tract infections include members of the Enterobacteriaceae family, streptococci and staphylococci species and perch. In addition, K.penumoniae is another important gram-negative bacterium that causes urinary tract infections. With the PCR technique, unseen bacterial species can be detected using standard clinical microbiology methods. In this study, the

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Publication Date
Fri Dec 31 2021
Journal Name
Political Sciences Journal
The development of Russian-Iraqi relations for the period (2011-2019)
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Receipt date: 12/28/2020 accepted date: 20/1/2021 Publication date: 12/31/2021

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Russia has emerged as a rising and influential power in the international arena, especially with Vladimir Putin's assumption of power and his desire for the rise of Russia and the end of the "unipolarism" represented by the hegemony of the United States of

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Crossref
Publication Date
Thu Jan 31 2019
Journal Name
Journal Of The College Of Education For Women
Iraqi-US relations in the light of the strategic framework agreement
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The United States has stood by Iraq and supported militarily and morally, but the relationship did not quickly be strained again before August 1990, when the oldest former political system in Iraq after Iraqi troops entered the territory of Kuwait, the United States stood beside Kuwait because the two parties link military ties opted States United to support the Kuwaiti side relying on the resolutions passed by the UN security Council, the United States and found in this issue right opportunity to execute the mechanics of meddling in Iraqi affairs and the various means of political, economic, military, and methods for dealing with Iraq, especially after finding the impediment standing in front of the implementation of its goals The strat

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