The condition known as hypothyroidism is common in women, even in those who are fertile. The quantity and caliber of follicles present in the ovary at any one moment are known as the ovarian reserve. Individuals who are susceptible to a decreased ovarian reserve ought to have an assessment of their ovarian reserve conducted. The purpose of this research is to assess the impact of hypothyroidism on Iraqi women's ovarian reserve using Inhibin B hormone and hormone tests FSH, LH. There was no discernible variation in the average (±SD) age from (20 to 40) years of the patient group compared to the control group (p-value 0.08). However the mean BMI of the patients were statistically significantly different from the controls (P- value 0.006).Women with positive and negative anti-TPO, those with overt and subclinical hypothyroidism, difference in mean values of studied parameters (Inhibin B, FSH and LH) in patients group according to regularity of menstrual cycle (regular vs. irregular), with significant decrease in mean value of Inhibin B in irregular menstruated patients when compared to regular ones (P -value 0.038). There was no significant difference in mean values of other measured parameters. A noteworthy inverse relationship was seen between BMI and inhibin B (r = -0.34, P- value 0.02). This study indicated that, regardless of the cause or state of thyroid function, women with established hypothyroidism should have their serum levels of Inhibin B measured.
