A group of amino derivatives [4-aminobenzenesulfonamide,4-amino-N¹ methylbenzenesulfonamide, or N¹-(4-aminophenylsulfonyl)acetamide] bound to carboxyl group of mefenamic acid a well known nonsteroidal anti-inflammatory drugs (NSAIDs) were designed and synthesized for evaluation as a potential anti-inflammatory agent.  In vivo acute anti-inflammatory activity of the final compounds (9, 10 and 11) was evaluated in rat using egg-white induced edema model of inflammation in a dose equivalent to (7.5mg/Kg) of mefenamic acid. All tested compounds produced a significant reduction in paw edema with respect to the effect of propylene glycol 50% v/v (control group). Moreover, the 4-amino-N-methylbenzenesulfonamide derivative (c

This study includes design and synthesis of new non-steroidal anti-inflammatory agents (NSAIDs) with expected cyclooxygenase-2 (COX-2) selective inhibition to achieve better activity and low gastric side effects. Two series of compounds have been designed and synthesized as potential NSAIDs,these  are:     Salicylamide derivatives (compounds 3,4,5 ) and Diflunisal derivatives (compounds 10&11). In vivo acute anti-inflammatory effect of one of the synthesized agents (compound 3)  was evaluated in the rat using egg-white induced paw edema model of inflammation. Preliminary pharmacological study revealed that compound 3 exhibited less anti-inflammatory effect  compared to that of aspirin after

This study is pointed out to estimate the effectiveness of two solvents in the extraction and evaluating the active ingredients and their antioxidant activity as well as anti-cancer efficiency. Therefore, residues from four different Brassica vegetables viz. broccoli, Brussels sprout, cauliflower, and red cherry radish were extracted using two procedures methods: methanolic and water crude extracts. Methanol extracts showed the highest content of total phenolic (TP), total flavonoids (TF), and total tannins (TT) for broccoli and Brussels sprouts residues. Methanolic extract of broccoli and Brussels sprouts residues showed the highest DPPH· scavenging activity (IC₅₀ = 15.39 and 18.64 µg/ml). The methanol and water ex

In light of the increasing importance of interim financial statements they provided these lists of information that enables users of accounting information to make wise investment decisions and predict the company's activities in light of changes the updated rather than wait until the end of the year and accessing information provided by the annual financial statements. In light of this research has come to the most important set of conclusions the adoption of interim financial information has been audited by the external auditor to the availability of basic qualitative characteristics in the accounting information contained in the (appropriate and timely manner, reliability and comparability) and this in turn leads to the impact on reli

The research aims to achieve proof of convergence between optimal costs and standard costs in calculating costs for the economic unit, support efforts aimed at adopting optimal costs in cost accounts and accounting thought in general, and achieve benefit from the theory of convergence between optimal costs and standard costs in the field of achieving actual costs in The economic unit in order to reduce and converge, and this came to address the possibility of adopting the concept of optimal costs in the production costs calculations for the purposes of rationalizing administrative decisions, and rationalizing the preparation of financial statements within management accounting.

The research concluded that

      تُعد أبرز الإشكاليات التي تثيرها ظاهرة تعدد الجنسية مسألة تعيين القانون الواجب التطبيق على النزاع المشوب بعنصر أجنبي عندما تشير قواعد الإسناد الوطنية فيه إلى تطبيق القانون الشخصي, الأمر الذي ترتب عليه إجتهاد الفقه والقضاء في هذا المجال إلى معايير عدّة يمكن تطبيقها لترجيح أحدى الجنسيات التي يحملها متعدد الجنسية, فضلاً عن موقف التشريعات الوطنية الحديثة التي تبنت بعض ما رجح من هذه المعايير, ويمكن تج

نشأت المدرسة الليبرالية (Liberalism) التي سعت لبناء نموذجها الفكري (Paradigm) في التحليل السياسي الذي على أساسه تقوم بتحليل النشاط البشري السياسي على المستوى المحلي والداخلي والدولي، والتعرف على الدوافع خلف ذلك النشاط، حيث إهتم البشر في بناء التفاهمات والاتفاقيات والمعاهدات وإعطاء الالتزامات وصياغة القواعد والاطر والقوانين المنظمة للمجتمع الإنساني داخليا ام دوليا، ووضع المعايير الملزمة لتلبية حاجات ومصالح إن

ملخـــص البحــــث

       تناولتْ هذهِ الورقاتُ جُزئيّةً من جُزئيّاتِ قضيّةِ المنعِ من الصّرفِ أو التنوينِ في العربيّةِ، وهي جزئيّةٌ لم تُغفلْها المصادرُ النحويّةُ بدءًا من كتابِ سيبويهِ الذي أشارَ في كثيرٍ من أمثلتِهِ إلى التخييرِ المطلقِ بينَ الصرفِ والمنعِ، وأشار في مفرداتٍ أخرى إلى جواز صرفها ومنعها على وَفق اعتباراتٍ معيّنةٍ، لا بإطلاقها. والغاي