Genetics play a major role in diabetic retinopathy DR, which is a leading cause of blindness worldwide. Although the factors such as how long a person has had diabetes and high blood sugar are important, the wide variation and progression of DR indicates to a clear genetic influence. Early studies focusing on a few candidate genes (such as VEGF) produced conflicting and population-dependent results. This confirmed the multifactorial nature of the disease and the limitations of small-scale studies. Conversely, genome wide association studies (GWAS) have provided more consistent findings in detection a new genes related to DR. For example, rs2239785 variant which is located in the APOL1 gene was found to be a high risk factor for diabetic mac

The liver is one of the largest glands in the digestive system and performs 13 various functions, including the secretion of hormones and enzymes. The gallbladder serves as a storage reservoir for secretions before they are released into the digestive system through the duodenum. The bile ducts branch from the liver’s lobes and ultimately connect to the digestive system, making this structure significant and distinct among different animal species. This review focuses on the differences between dogs and cats, highlighting the importance of these differences from both health and pathological perspectives. After conducting a detailed scientific review of the biliary tree in dogs and cats, we concluded that cats are more susceptible

Bipedal robots, designed to replicate human locomotion, face significant balance challenges due to instability and high degrees of freedom. This study examines dynamical models, balance control strategies, and locomotion methodologies. Dynamical models are categorized into simplified, centroidal dynamics, and whole-body dynamics models. Simplified models, such as the Linear Inverted Pendulum Model (LIPM), approximate the robot as a point mass at the Center of Mass (CoM) but neglect upper-body dynamics and complex terrain interactions. Centroidal dynamics models incorporate CoM motion, contact forces, and angular momentum for improved disturbance rejection but require extensive computational resources. Whole-body models achieve high

This review sums up the developments in the biological activity of tetrazole active derivatives in recent days. Some of the deliberated derivatives of tetrazole are at present actively scientifically studied; some of them have biological activity that enables them to be studied further in the future as a drug for various biological activities. This review seeks to offer a comprehensive analysis of the efficacy and clinical advantage of biological activity for tetrazole derivatives.

Arabic language processing with artificial intelligence has evolved significantly in the past decades, from traditional rule- and dictionary-based techniques, through statistical models to modern deep and transformer models. This review intends to present an overview of the most well-known Arabic models as well as datasets used for its training, and the main practical applications such as sentiment analysis, machine translation, speech recognition, and smart assistant. AI-based Arabic NLP has had good progress in the previous decades, from rule and dictionary-based approaches to statistical methods and deep transformative learning models nowadays. In addition to it, the most popular state-of-the-art models that are fine-tuned for the Arabi

According to the famous saying of the medieval physician Paracelsus, "There is no substance without poison. Only the dose determines the extent of the toxic effect." Here, the effect of monosodium glutamate (MSG) on human health and the risks to the health of its frequent use in the short term was addressed and the long term was evaluated according to the studies of several researchers specializing in this regard. Monosodium glutamate (MSG) is known as one of the most popular food additives that classified as a flavor enhancer. Parts of the evidence were reviewed from the literature explaining its effect on immune system cells in addition to metabolic disorders by exposing individuals to obesity and what is known as metabolic syndrome, as w