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Four different spectrophotometric methods are used in this study for the
determination of Sulfamethoxazole and sulfanilamide drugs in pharmaceutical
compounds, synthetic samples, and in their pure forms. The work comprises
four chapters which are shown in the following:
Chapter One: Includes a brief for Ultraviolet-Visible (UV-VIS) Absorption
spectroscopy, antibacterial drugs and sulfonamides with some methods for
their determination.
The chapter lists two methods for optimization; univariate method and
multivariate method. The later includes different types, two of these were
mentioned; simplex method and design of experiment method.
Chapter Two: Includes reaction of the two studied drugs with sodium nitrite
and hydrochloric acid for diazo
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