This study was done to test the activity of some plant extracts as antioxidant agents. The plants were (Morus rubra, Hibiscus sabdariffa L ., Rhus coriaria L., Anethum graveolens and Petroselinum sativum).
Ethanolic 98% (24 hours/ 25˚c) and distilled water (30 minutes/ 25˚c have been used for extraction.The Total phenols, total flavonoids, total anthocyanin, antioxidant activities were studied.
The extract of Morus rubra was chosen because it has a higher antioxidant activity.
The phenolic extract of Morus rubra was prepare and examined by application it in burger . The antioxidant activity test of Morus rubra was made before and after 3,6 days of cold storage. The sensory evaluation of all treatments were done within 5,10 days.
The results showed:
There was significant different between ethanolic extract and water extract in total phenols and flavonoids compound, the ethanolic extract of Morus rubra shown superior phenolic compound contain (23.3 mg GAE/ gr.), water extract of Morus rubra L., Showed height phenolic compound (20 mg GAE/ gr.).
Ethanolic and water extracts of Morus rubra have a higher Flavonoids (81.1, 69.8 μg /g Rutin Equv.). The Morus rubra shown superior Anthocyanin compound 56.3 μ g Cyanidin 3- glucoside/ gr. The antioxidant activity different according to type of plant and concentration, the ethanolic extract of Morus rubra gave higher antioxidant activity(88.9%) compared with other extract and α- tocopherol (86.5%) and lower from BHT (97 %).
The extract was added to burger at (0.04, 0.08, 0.12gr./ 100 gr.) which were stored at 4C for 5,10 days the peroxide value decreased as the extract concentration was increased.
Abstract
Itraconazole is a triazole antifungal given orally for the treatment of oropharyngeal and vulvovaginal candidiasis, for systemic infections including aspergillosis, candidiasis, and for the prophylaxis of fungal infections in immunocompromised patients.
The study aimed to formulate a practical water-insoluble Itraconazole, with insufficient bioavailability as nanosuspension to increase aqueous solubility and improve its dissolution and oral bioavailability.
Itraconazole nanosuspension was produced by a
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