Background: Plants used in folk medicine for
the treatment of peptic ulcer diseases is a very
promising approach to overcome the limitations of
classical medicines.
Aim: To explore the efficacy of medicinal
plants, namely turmeric, garlic and marshmallow,
in eradication of H. pylori.
Methods: This prospective study was carried out
on 225 of well-known dyspeptic patients who were
divided into four groups; a control group (received
classical medical therapy) and three other groups
that received one of the three medicinal plants,
plus the same therapy used in the control group.
The follow up was done by using a questionnaire
form, endoscopic examination, and determination
of serum levels of anti H.pylori antibodies &
gastrin by using ELISA test. In addition, liver
enzymes were monitored by using spectrophotometer
to prove the safety of medicinal plants.
Results: The rate of recurrence of peptic ulcer
disease was decreased in patients who received the
combined therapy when compared to the patients
in control group. Medicinal plants were effective
in decreasing the recurrence of H. pylori infection
when each one of them was used in combination
with the medical therapy without causing harmful
effects on the liver.
Conclusion: Turmeric, garlic & marshmallow
are effective in management of peptic ulcer with
low cost.
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