Background : Coronary artery disease is theunderlying cause in approximately two thirds of
patients with systolic heart failure ;
Coronary artery angiogriphy may be useful to
define the presence ,
Anatomical characteristics ,and functional
significance of Coronary artery disease in
selected heart failure patients with or without signs
and aymptoms of Coronary artery disease.
Objectives: to verify the clinical usefulness of
coronary angiography (CA) in congestive heart
failure (CHF) patients with no history of ischemic
heart disease and to identify predictive factors for
performing coronary angiography to patients with
congestive heart failure with no obvious ischemia.
Methods :this is a cross-sestional study conducted
Ibn al –Bitar center for cardiac surgery during a
period between November 2009 and November
2010 ;all included patients have symptomatic LV
dyfunctional with NYHA functional class II or
more with no clinical evidence of IHD .History,
physical examination had been performed for each
patient , in addition ti blood tests ,ECG ,CXR,
echocardiography and Coronary angiogriphy
Results :Among 112 patients with symptomatic
LV dysfunction of unknown cause enrolled in this
study male :female ratio 3:1 their age (17 -77 years
)there were 14 patients (12.5%)with significant
Coronary artery disease , statistical analysis
between CADand non CAD group show :the CAD
were more common in male 11 patients (78% )
smokers(1)Were female , 25 patients (22.3%) were
diabetic , 25 diabetic (22.3%) were hypertensive
,50 diabetic (44.6%) were smokers . 4 diabetic3.5) with family history of dilatedhyperlipidemia and 3 diabetic (2.6%) ) with
family history ischemic heart disease (IHD in
close relative at age <50 years in men and <55
years in women ) as demographic distribution of
patients in table 1 .coronary angiography show
that are 14 patients (12.5%) with significant
coronary artery disease (CAD) and 98 patients
(87.5%) with significant coronary artery disease
. as shown in figure 1 . eleven patients (78%) of
patients (22%) were female statistical analysis
shows that the male is more predominant in
CAD groups as shown in table 2 . twelve
patients (85.7%) of patients with CAD were
smokers while only 38 patients (38.7%) were
smokers in non CAD group . statistical analysis
shows there is significant difference between
the two groups ( p value < 0.01 ) as shown in
table 3 .nine patients (64.2%) of patients with
CAD were diabetics while 16 patients
(16.3%)were diabetics in non CAD group ,
statistical analysis shows there is significant
difference between the two groups (p value <
0.005) as shown in table (3) .there is no
statistical between the mean of left ventricular
ejection fraction of CAD group ( 37 ±10 %) and
that of non CAD (36±9 % ) , p value > 0.5 as
shown in table 6 . figure 2 revealed that LAD
lesion was most common coronary artery lesion
which represent 12 (85%) followed by in order
of frequency LCX 42 % ,RCA 28% and LMS
7% ; in addition to that 57% with single vessel
disease ,14.2% with 2 vessel disease and
28.4%with r vessel disease (2)Leads , ST
depression ≥1 mm or deep T wave inversion
had been excluded
(
This study aims to study the effect of gout disease on complete blood picture and biochemical parameters and some non-enzymatic antioxidants, some tracing elements and lipid peroxidation ,in outpatients with gout disease at Al-Ramadi Teaching-Hospital ,Al-Razi Hospital and the study duration from Octo.2013-to May 2014.(50) blood samples were collected from patients with age groups (30-80 years) from both sexes (28 males,22 females),a (30) blood samples (15 males,15 females) were collected from normal individuals as a control group with age groups (27-75 years). Hematological measurement showed no significant differences in size compressed blood cells, the percentages in ( 45.15 +4.99 and 46.87+6.30) % in patient and control groups respect
... Show More
Evaluating treatment effect on interferon-alpha in female patients with systemic lupus erythematosus: a case-control study
Background: Treatment modalities of acromegaly and disease control impact differently on glucose homeostasis and lipid changes, and consequently on cardiometabolic risk. Aim: To investigate the possible association of lipid profile changes with the glycemic control status in acromegaly patients treated with octreotide LAR. Methods: This cross-sectional study included 52 Iraqi patients with acromegaly treated with octreotide LAR and not using statins. Demographic, anthropometric, and clinical data were collected, as well as the duration of Octreotide LAR administration. The glycemic state was assessed and classified as DM, prediabetes, or normal. Plasma levels of triglycerides, LDL cholesterol, HDL cholesterol, and non-HDL were evalu
... Show More
In individuals with type 2 diabetes mellitus (T2DM), the cannabinoid receptor 1 (CNR1) gene polymorphism has been linked to diabetic nephropathy (DN). Different renal disorders, including DN, have been found to alter cannabinoid (CB) receptor expression and activation. This cross-sectional study aimed to investigate the relationship between CNR1 rs1776966256 and rs1243008337 genetic variants and the risk of developing DN in Iraqi patients with T2DM. The study included 100 patients with T2DM, divided into two groups: 50 with DN and 50 without DN. Genotyping of CNR1 rs1776966256 and rs1243008337 polymorphisms was conducted using PCR in DN patients and control samples. The distribution of rs1776966256 and rs1243008337 genotypes and alleles bet
... Show More
(2)
(2)
(3)
(2)
he study aimed to purify of Leucine aminopeptidase (LAP) from sera of hyperthyroidism patients and its relation to some thyroid hormones (TSH, T 3 , T 4 ) of subclinical hyperthyroidism and hyperthyroidism patients with lipid peroxidation levels that may be play a role in this diseases. Specimens were collected during the time from Nov 2017 until Jan 2018 from Endocrine and Diabetes Center, blood samples were collected from fifty healthy control and one hundred patients, patients were divided into two groups consisted of (50) with hyperthyroidism and (50) with subclinical hyperthyroidism. The aged for all subjects ranged (15-60) years with body mass ranged ((25- 29) kg/m 2 . The purification is done by addition of ammonium sulfate, dial
... Show MoreHypothyroidism is the decrease in thyroid hormones production and thyroid gland function. Hashimoto’s thyroiditis is the most common cause of hypothyroidism with production of autoantibodies directed toward autoantigens thyroglobulin (Tg) and thyroid peroxidase (TPO). This study was carried out to determine and compare serum and salivary levels of thyroid antibodies (TPO-Ab and Tg- Ab) in hypothyroid patients (with and without periodontitis) and healthy control; as well as to estimate the possibility to evaluate and measured these antibodies in the saliva as measured in the serum. Serum and saliva samples were collected from sixty hypothyroid patients with age ranged (20-64) years (30 of patients were with periodontitis and 30 without per
... Show MoreBackground: Gingival crevice fluid (GCF) is a mixture of substances derived from serum, leukocytes, and structural cells of periodontium and oral bacteria. These substances possess a great potential for serving as indicators of periodontal disease and healing after therapy the main purpose of this study was to find if there is a difference in albumin concentration between healthy and diseased periodontal tissues and to compare between diseased group according to pocket depth Materials and methods: total sample composed of 60 pockets found in 35 patients all of them had no history of any systemic disease, The samples were divided in to three main group that include two diseased groups divided according to the depth of the periodontal pocket
... Show More
Alopecia areata is a common disorder, hypothesized to be autoimmune in etiology. Cortisone taken orally may stimulate new hair growth. Prednisone (orally administered steroid (has proved effective for patients with alopecia areata, but its potential side effects include weight gain, metabolic abnormalities, acne and menstrual problems.
This clinical study was designed to assess the clinical significance of the nutrient antioxidants (vitamin A, vitamin E and vitamin C) in reducing the dose of corticosteroids (prednisolone), and as a consequence, their side effects in patient with alopecia. The results of this study reveal the potential clinical significance of the therapy for two months with these antioxidants in reducing the dose
... Show More