Background : Coronary artery disease is theunderlying cause in approximately two thirds of
patients with systolic heart failure ;
Coronary artery angiogriphy may be useful to
define the presence ,
Anatomical characteristics ,and functional
significance of Coronary artery disease in
selected heart failure patients with or without signs
and aymptoms of Coronary artery disease.
Objectives: to verify the clinical usefulness of
coronary angiography (CA) in congestive heart
failure (CHF) patients with no history of ischemic
heart disease and to identify predictive factors for
performing coronary angiography to patients with
congestive heart failure with no obvious ischemia.
Methods :this is a cross-sestional study conducted
Ibn al –Bitar center for cardiac surgery during a
period between November 2009 and November
2010 ;all included patients have symptomatic LV
dyfunctional with NYHA functional class II or
more with no clinical evidence of IHD .History,
physical examination had been performed for each
patient , in addition ti blood tests ,ECG ,CXR,
echocardiography and Coronary angiogriphy
Results :Among 112 patients with symptomatic
LV dysfunction of unknown cause enrolled in this
study male :female ratio 3:1 their age (17 -77 years
)there were 14 patients (12.5%)with significant
Coronary artery disease , statistical analysis
between CADand non CAD group show :the CAD
were more common in male 11 patients (78% )
smokers(1)Were female , 25 patients (22.3%) were
diabetic , 25 diabetic (22.3%) were hypertensive
,50 diabetic (44.6%) were smokers . 4 diabetic3.5) with family history of dilatedhyperlipidemia and 3 diabetic (2.6%) ) with
family history ischemic heart disease (IHD in
close relative at age <50 years in men and <55
years in women ) as demographic distribution of
patients in table 1 .coronary angiography show
that are 14 patients (12.5%) with significant
coronary artery disease (CAD) and 98 patients
(87.5%) with significant coronary artery disease
. as shown in figure 1 . eleven patients (78%) of
patients (22%) were female statistical analysis
shows that the male is more predominant in
CAD groups as shown in table 2 . twelve
patients (85.7%) of patients with CAD were
smokers while only 38 patients (38.7%) were
smokers in non CAD group . statistical analysis
shows there is significant difference between
the two groups ( p value < 0.01 ) as shown in
table 3 .nine patients (64.2%) of patients with
CAD were diabetics while 16 patients
(16.3%)were diabetics in non CAD group ,
statistical analysis shows there is significant
difference between the two groups (p value <
0.005) as shown in table (3) .there is no
statistical between the mean of left ventricular
ejection fraction of CAD group ( 37 ±10 %) and
that of non CAD (36±9 % ) , p value > 0.5 as
shown in table 6 . figure 2 revealed that LAD
lesion was most common coronary artery lesion
which represent 12 (85%) followed by in order
of frequency LCX 42 % ,RCA 28% and LMS
7% ; in addition to that 57% with single vessel
disease ,14.2% with 2 vessel disease and
28.4%with r vessel disease (2)Leads , ST
depression ≥1 mm or deep T wave inversion
had been excluded
(
Background: Ankylosing spondylitis (AS) is inflammation of the sacroiliac joints and spine, associated with clinical symptoms such as pain and stiffness in the vertebral column, after which, in a considerable number of individuals, new bone growth occurs. Objective: The current research study attempted to find out whether the presence of SNPs in TNF receptor [TNFRSF1A (rs767455), TNFRSF1B (rs1061622)] encoding genes could influence patients' outcomes to etanercept in a specimen of Iraqi AS patients. Patients and methods: Sixty patients with established AS receiving only etanercept were selected to be enrolled in this research with a mean age of 40.75 ± 8.67 years, 51 patients of them were males and only 9 patients were females. Patients we
... Show MoreWhile hepatitis viruses A–E are established, emerging evidence points to additional, novel viral hepatitis agents. The torqueteno virus (TTV) has garnered interest due to its prevalence among patients with hepatitis, suggesting potential hepatotropism.
This study was conducted to detect TTV antigens in individuals infected with chronic hepatitis B (HBV) and/or C (HCV) using molecular diagnostics and to explore any associations between TTV presence and demographic characteristics of the cohort.
Abstract: Fluoroquinolones drugs are an important class of wide
... Show MoreAnalyze the relationship between genetic variations in the MTHFR gene at SNPs (rs1801131 and rs1801133) and the therapy outcomes for Iraqi patients with rheumatoid arthritis (RA). The study was conducted on a cohort of 95 RA Iraqi patients. Based on their treatment response, the cohort was divided into two groups: the responder (47 patients) and the nonresponder (48 patients), identified after at least three months of methotrexate (MTX) treatment. A polymerase chain reaction-restriction fragment length polymorphism (PCR–RFLP) technique was employed to analyze the MTHFR variations, specifically at rs1801133 and rs1801131. Overall, rs1801131 followed both codominant and dominate models, in which in
Background: A recent discoveries used for reconstruction in maxillofacial surgery is the composite bone graft materials. The availability of collagen I matrix make our choice to use this material in surgery .It is biomaterials that its structure could be modified by simple techniques. Studies to find a new materials use for bone reconstruction is to overcome the disadvantages of autogenous bone and the synthetic resorbable bone substitutes.
Objectives: This study was done to evaluate the effect of biphasic calcium phosphate collagen composite (ccpc) on healing of bone defects after oral surgical procedures.
Type of the study: A cross sectional study.
Method: It involved 60 patients, 35 male and 25 female, age (15-
... Show MoreBackground: Modifications of life style are often critically important to adequately control excising hypertension.
Objective: :to determine the source of information regarding hypertension and lifestyle modification practices in the management of hypertension in a sample of Iraqi hypertensive patients.
Type of the study: Across-sectional study.:
Methods: The study was conducted over a period of two months during November and December 2015 at Primary Health Care center of Baghdad Al-GidedaAwaland Bab Al Mudhum primary health care centers. The sample included 219 hypertensive patients (102 females and 117males). They were subjected to a
... Show MoreThere is a suggestion that an antidiuretic hormone-induced decrease in diuresis might contribute to the rapid relief of the acute pain in renal colic. This study was designed to evaluate the efficacy of desmopressin nasal spray compared with diclofenac given intramuscularly in patients with acute renal colic. The study included 75 patients randomized into three different groups; group A received desmopressin (40 μg, nasal spray), group B diclofenac (75 mg) intramuscularly and group C, both desmopressin and diclofenac. Pain was assessed using a visual analogue scale (a 10-cm horizontal scale ranging from `no pain' to `unbearable pain') at baseline, 10, 20 and 30 min after administering t
... Show MoreBackground: Radioactive iodine-131 therapy is highly effective in treating patients with hyperthyroidism. An ablative dose is preferred by a number of endocrinologists, and, a fixed dose protocol seems to be better than a calculated dose in real practice.
Objective: To check for hypothyroidism in hyperthyroid patients one year after RAI therapy, comparing between the results of high ablative versus usual dosages of RAI-131.
Methods: This study included 174 hyperthyroid patients, 101 males and 73 females, divided into 2 groups, the first consisted of 162 patients given a usual fixed dose of RAI while the second consisted of 12 patients given a high fixed ablati
... Show MoreCovalent modification of protein by drugs may disrupt self-tolerance, leading to lymphocyte activation. Until now, determination of the threshold required for this process has not been possible. Therefore, we performed quantitative mass spectrometric analyses to define the epitopes formed in tolerant and hypersensitive patients taking the β-lactam antibiotic piperacillin and the threshold required for T cell activation. A hydrolyzed piperacillin hapten was detected on four lysine residues of human serum albumin (HSA) isolated from tolerant patients. The level of modified Lys541 ranged from 2.6 to 4.8%. Analysis of plasma from hypersensitive patients revealed the same pattern and leve