Background: Asthma is a common chronic disease in children in which the body’s airways swell, preventing the lungs from filling with air, there are many different inflammatory cells involved in asthma which can synthesize and release cytokines which are recognized to be important in chronic inflammation and play a critical role in the inflammatory response. Objectives: to assess the local effect of ICS on oral tissue by measuring Interlukine-12 level and Candida albicans colony in saliva among12 year's old asthmatic children who were collected from AL- Zahra Center Advisory for Allergy and Asthma, and compares them with non-asthmatic children of the same age and gender.Type of the study: Cross –sectional study.Methods: The total sample composed of 60 children 30 asthmatic children who received medium dose of ICS/day for two years and thirty non-asthmatic children. The unstimulated saliva was collected under standard condition and then analyzed for assessment of IL-12 level and Candida albicans colony. Results: Among asthmatic and non- asthmatic children; the mean rank of salivary IL-12 was found to be higher among C. albicans carrier group than without C.albicans with statistically highly significant difference (P< 0.01). Concerning each gender the same findings were recorded. Concerning IL-12 + and IL-12-, results reported that the mean rank differences were found statistically non-significant difference (P>0.05). Concerning each gender the same results were reported. Concerning gender differences, data analysis showed that there were no statistically significant differences. The results illustrated that the mean rank of salivary IL-12 was found to be higher among asthmatic than non- asthmatic children with statistically significant difference (P=0.016). Concerning each gender, similar results were recorded as the difference was not significant (P>0.05). For C.albicans carrier asthmatic and non- asthmatic children and total asthmatic and non- asthmatic children, the relation between the IL-12 concentration and C.albicans quantities were strong highly significant in positive directionConclusions: The findings of the present study showed that the asthmatic disease and oral candida colonization play an important role in elevation of the IL-12 level in saliva.
Albizia lebbeck biomass was used as an adsorbent material in the present study to remove methyl red dye from an aqueous solution. A central composite rotatable design model was used to predict the dye removal efficiency. The optimization was accomplished under a temperature and mixing control system (37?C) with different particle size of 300 and 600 ?m. Highest adsorption efficiencies were obtained at lower dye concentrations and lower weight of adsorbent. The adsorption time, more than 48 h, was found to have a negative effect on the removal efficiency due to secondary metabolites compounds. However, the adsorption time was found to have a positive effect at high dye concentrations and high adsorbent weight. The colour removal effi
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A laboratory experiment was carried out at the College of Agriculture University of Baghdad in 2017. The aim was to improve the anatomical and physiological traits of broad bean seedling under salt stress by soaking it in salicylic acid. The concentrations of salicylic acid were 0, 10, and 20 mg L-1 and the electrical conductivity levels were 0, 3, and 6 dS m-1. The complete randomized design was used with four replications. The increasing of salicylic acid concentration up to 10 mg L-1 led to increasing the stem cortex thickness, stem vascular bundles thickness, and root cortex thickness significantly by (34.9,36.7,and 55 µm) respectively, while the treatment of 20 mg L-1 led to decreasing these traits by (28.2, 27.8, and 48.1 µm
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Combination of natural poly-phenolic compounds with chemotherapeutic agents is recently being a novel strategy in cancer therapy researches owing to their potential antioxidant and anti-inflammatory properties that modulate several intracellular signaling pathways.
Resveratrol and Baicalein are well known poly-phenolic compounds that belong to stilbene and flavone subclasses, respectively.
This study aims to investigate the possible enhancement effect of resveratrol and Baicalein when combined with doxorubicin using a different combination ratio and applied on two cancer cell lines: HCT116 (colorectal cancer cells) and HepG2 (hepatocellular cancer cells). It also investigates the possibility of such natural compounds to p
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