Background :Infectious disorders in general have high morbidity and mortality.. CNS infections include many disorders like bacterial meningitis, tuberculous and other subacute and chronic meningitis, viral meningitis, cerebral abscess, spinal cord infections, and others.
Objective: To assess our locality about prevalence of CNS infections , to have more awareness regarding CNS infections, and to try to find the proper way to reduce their prevalence and to treat them in appropriate way.
Method :We revised the records of all the cases of CNS infections excluding cases of spinal cord infections who were admitted in the wards of neuroscience hospital over the previous two years ( from July/2010 to June 2012 ),those were 132 cases.Seasonal incidenceand other clinical aspects and other parameters like age , sex, , fever are extracted and recorded
Results: The most common CNS infections in sequence from the most to the least were bacterial meningitis, viral encephalitis, tuberculous meningitis, viral meningitis, and cerebral abscess.
The most common age group which is affected by CNS infections was below 10 years.
Males are affected more than females taking in consideration all types of infection.
P values were statistically significant for age, fever, signs of meningeal irritation, focal neurological deficit, and seizures.
Conclusion : The total rate of admission of CNS infections in our series was lower than other study.
The most frequent type of CNS infections was bacterial meningitis which is the same as most of the studies.
Males are affected more than females in our study in all types of CNS infections, this was approximate to other studies except for tuberculous meningitis.
Bacterial meningitis and viral encephalitis were more common in preschool children in our study.
Fever rate in bacterial and tuberculous meningitis was different from other studies.
Seizure rate in bacterial meningitis and viral encephalitis was approximate to other results.
Rate of focal deficit in viral encephalitis and tuberculous meningitis was different from other studies.
Rate of CSF protein elevation in all CNS infections was approximate to other studies.
Rate of hypoglycorrhachia was different from other studies only in tuberculous meningitis.
CSF pleocytosis was approximate to other studies in all types of CNS infections.
The two most common types of CNS infections , bacterial meningitis and viral encephalitis, are more common in preschool age groups.
The Ligand 6,6--(1,2-benzenediazo) bis (3-aminobenzoicacid) derived from o-phenylenediamine and 3-aminobenzoicacid was synthesized. The prepared ligand was identified by Microelemental Analysis, 1HNMR, FT-IR and UV-Vis spectroscopic techniques. Treatment of the ligand with the following metal ions (CoII, NiII, CuII and ZnII ) in aqueous ethanol with a 1:1 M:L ratio and at optimum pH. Characterization of these compounds has been done on the basis of elemental analysis, electronic data, FT-IR and UV-Vis, as well as magnetic susceptibility and conductivity measurements. The nature of the complexes formed were studied following the mole ratio and continuous variation methods, Beer's law obeyed over a concentration range (1×10-4 - 3×10-4 M). H
... Show MoreBackground: The bond strength of root canal sealers to dentin was important for maintaining the integrity of the seal in root canal filling in both static and dynamic situations. In a static situation, it should eliminate any space that allowed the percolation of fluids between the filling and the wall while in a dynamic situation; it was needed to resist dislodgement of the filling during subsequent manipulation. Materials and Methods: Forty mandibular premolars were selected for this study. All canals were instrumented using ProTaper rotary instruments. Instrumentation was done with copious irrigation of 5.25% sodium hypochlorite. Roots were randomly divided into four groups according to the type of cleaning and method of root canal irrig
... Show MorePhytochemical Screening and Antibacterial Effect of Stevia Rebaudiana (Bertoni) Alcoholic Leaves Extract on Streptococcus Oralis (Dental Plaques Primary Colonizer), Manar Ibrahim
Background: Enforcement of sustainable and green chemistry protocols has seen colossal surge in recent times, the development of an effective, eco-friendly, simple and novel methodologies towards the synthesis of valuable synthetic scaffolds and drug intermediates. Recent advances in technology have now a more efficient means of heating reactions that made microwave energy. Efforts to synthesize novel heterocyclic molecules of biological importance are in continuation. Microwave irradiation is well known to promote the synthesis of a variety of organic and inorganic compounds. The aim of current study was to conceivea mild base mediated preparation of novel Schiff base of 2-Acetylpheno with trimethoprim drug (H2TPBD) and its complexes w
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