Preferred Language
Articles
/
jkmc-1106
Viable Strategies to Increase Clinical Trial Patient Diversity
...Show More Authors

In the United States, the pharmaceutical industry is actively devising strategies to improve the diversity of clinical trial participants. These efforts stem from a plethora of evidence indicating that various ethnic groups respond differently to a given treatment. Thus, increasing the diversity of trial participants would not only provide more robust and representative trial data but also lead to safer and more effective therapies. Further diversifying trial participants appear straightforward, but it is a complex process requiring feedback from multiple stakeholders such as pharmaceutical sponsors, regulators, community leaders, and research sites. Therefore, the objective of this paper is to describe three viable strategies that can possibly increase the diversity of clinical trial participants: (1) Diversification of the clinical research workforce. (2) Adoption of the diversity in site assessment tool, and (3) incorporation of decentralized clinical trial technologies into clinical trial designs.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sun Apr 02 2023
Journal Name
Journal Of Oral Microbiology
Current concepts in the pathogenesis of periodontitis: from symbiosis to dysbiosis
...Show More Authors

View Publication
Crossref (360)
Crossref
Publication Date
Sat Aug 02 2025
Journal Name
Engineering, Technology & Applied Science Research
Linking the Fatigue Resistance of Nano-Modified Binders to Mixture Cracking
...Show More Authors

This study examined the correlation between binder-level fatigue properties and mixture-level cracking resistance in asphalt binders modified with five Nanomaterials (NMs): Nano-Silica (NS), Nano-Alumina (NA), and Nano-Titanium dioxide (NT) at 2%, 4%, and 6% as well as Nano-Zinc oxide (NZ) and Carbon Nanotubes (CNTs) at 1%, 2%, and 3%. Modified binders were subjected to Rolling Thin-Film Oven Test (RTFOT) and Pressure Aging Vessel (PAV) aging and tested at 25 °C using the Linear Amplitude Sweep (LAS) test to determine fatigue life (Nf) and the fatigue parameter G*.sin δ. The corresponding asphalt mixtures were evaluated using the IDEAL-CT test. The results indicated strong correlations between binder and mixture performance for

... Show More
View Publication
Scopus (1)
Crossref (1)
Scopus Crossref
Publication Date
Wed Mar 23 2022
Journal Name
Modern Sport
Using Artificial intelligence to evaluate skill performance of some karate skills
...Show More Authors

Human beings are starting to benefit from the technology revolution that witness in our time. Where most researchers are trying to apply modern sciences in different areas of life to catch up on the benefits of these technologies. The field of artificial intelligence is one of the sciences that simulate the human mind, and its applications have invaded human life. The sports field is one of the areas that artificial intelligence has been introduced. In this paper, artificial intelligence technology Fast-DTW (Fast-Dynamic Time Warping) algorithm was used to assess the skill performance of some karate skills. The results were shown that the percentage of improvement in the skill performance of Mai Geri is 100%.

View Publication Preview PDF
Crossref (2)
Crossref
Publication Date
Tue Apr 11 2023
Journal Name
Sensors
EEG Signal Complexity Measurements to Enhance BCI-Based Stroke Patients’ Rehabilitation
...Show More Authors

The second leading cause of death and one of the most common causes of disability in the world is stroke. Researchers have found that brain–computer interface (BCI) techniques can result in better stroke patient rehabilitation. This study used the proposed motor imagery (MI) framework to analyze the electroencephalogram (EEG) dataset from eight subjects in order to enhance the MI-based BCI systems for stroke patients. The preprocessing portion of the framework comprises the use of conventional filters and the independent component analysis (ICA) denoising approach. Fractal dimension (FD) and Hurst exponent (Hur) were then calculated as complexity features, and Tsallis entropy (TsEn) and dispersion entropy (DispEn) were assessed as

... Show More
View Publication
Scopus (36)
Crossref (34)
Scopus Clarivate Crossref
Publication Date
Fri Mar 01 2024
Journal Name
Heliyon
Using unsafe traditional practices by Iraqi mothers to treat newborns' problems
...Show More Authors

View Publication
Scopus (2)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Thu Jan 04 2018
Journal Name
International Journal Of Molecular Sciences
Understanding the Progression of Bone Metastases to Identify Novel Therapeutic Targets
...Show More Authors

View Publication
Scopus (42)
Crossref (33)
Scopus Clarivate Crossref
Publication Date
Sat Aug 01 2020
Journal Name
Practice Periodical On Structural Design And Construction
Case Study to Evaluate Work-Zone Safety Technologies in Highway Construction
...Show More Authors

View Publication
Scopus (21)
Crossref (20)
Scopus Clarivate Crossref
Publication Date
Mon Dec 24 2018
Journal Name
Nano Letters
Personalized Nanotherapy by Specifically Targeting Cell Organelles To Improve Vascular Hypertension
...Show More Authors

View Publication
Scopus (29)
Crossref (25)
Scopus Clarivate Crossref
Publication Date
Sun Jul 12 2020
Journal Name
International Journal Of Research In Social Sciences And Humanities
SUBJECT REVIEW: STRATEGIC LEADERSHIP STYLE: FROM THE BOTTOM TO THE TOP
...Show More Authors

View Publication
Crossref
Publication Date
Mon May 01 2017
Journal Name
Cell Host & Microbe
Global Reprogramming of Host Kinase Signaling in Response to Fungal Infection
...Show More Authors

Cryptococcus neoformans (Cn) is a deadly fungal pathogen whose intracellular lifestyle is important for virulence. Host mechanisms controlling fungal phagocytosis and replication remain obscure. Here, we perform a global phosphoproteomic analysis of the host response to Cryptococcus infection. Our analysis reveals numerous and diverse host proteins that are differentially phosphorylated following fungal ingestion by macrophages, thereby indicating global reprogramming of host kinase signaling. Notably, phagocytosis of the pathogen activates the host autophagy initiation complex (AIC) and the upstream regulatory components LKB1 and AMPKα, which regulate autophagy induction through their kinase activities. Deletion of Prkaa1, the gene encodi

... Show More
View Publication
Scopus (40)
Crossref (48)
Scopus Crossref