Solubility problem of many of effective pharmaceutical molecules are still one of the major obstacle in theformulation of such molecules. Candesartan cilexetil (CC) is angiotensin II receptor antagonist with very low water solubility and this result in low and variable bioavailability. Self- emulsifying drug delivery system (SEDDS) showed promising result in overcoming solubility problem of many drug molecules. CC was prepared as SEDDS by using novel combination of two surfactants (tween 80 and cremophore EL) and tetraglycol as cosurfactant, in addition to the use of triacetin as oil. Different tests were performed in order to confirm the stability of the final product which includes thermodynamic study, determination of self-emulsificat

Objective: The objective of this study was to prepare nanosuspension of a practical water insoluble antiulcer drug which is lafutidine to enhance the solubility, dissolution rate with studying the effect of different formulation variables to obtain the best formula with appropriate physical properties and higher dissolution rate.Methods: Nanosuspension of lafutidine was prepared using solvent anti-solvent precipitation method using Polyvinylpyrrolidone K-90(PVP K-90) as the stabilizer. Ten formulations were prepared to show the effect of different variables in which two formulations showed the effect of stabilizer type, three formulations showed the effect of stabilizer concentration, two formulations showed the effect of combinatio

With the development of computer architecture and its technologies in recent years, applications like e-commerce, e-government, e-governance and e-finance are widely used, and they act as active research areas. In addition, in order to increase the quality and quantity of the ordinary everyday transactions, it is desired to migrate from the paper-based environment to a digital-based computerized environment. Such migration increases efficiency, saves time, eliminates paperwork, increases safety and reduces the cost in an organization. Digital signatures are playing an essential role in many electronic and automatic based systems and facilitate this migration. The digital signatures are used to provide many services and s

In this study, the response and behavior of machine foundations resting on dry and saturated sand was investigated experimentally. In order to investigate the response of soil and footing to steady state dynamic loading, a physical model was manufactured to simulate steady state harmonic load at different operating frequencies. Total of 84 physical models were performed. The footing parameters are related to the size of the rectangular footing and depth of embedment. Two sizes of rectangular steel model footing were tested at the surface and at 50 mm depth below model surface. Meanwhile the investigated parameters of the soil condition include dry and saturated sand for two relative densities 30% and 80%. The response of the footing was ela

The road transportation system is considered as major component of the infrastructure in any country, it affects the developments in economy and social activities. The Asphalt Concrete which is considered as the major pavement material for the road transportation system in Baghdad is subjected to continuous deterioration with time due to traffic loading and environmental conditions, it was felt that implementing a comprehensive pavement maintenance management system (PMMS), which should be capable for preserving the functional and structural conditions of pavement layers, is essential. This work presents the development of PMMS with Visual inspection technique for evaluating the Asphalt Concrete pavement surface condition; common types o

تهدف الدراسة الى بناء مقياس التهكم التنظيمي للمعنيين بالاتحاد العراقي المركزي بالكرة الطائرة. تحديد الدرجات والمستويات المعيارية لمقياس التهكم التنظيمي للمعنيين بالاتحاد العراقي المركزي بالكرة الطائرة.وقد استخدم الباحثون المنهج المسحي على مجتمع البحث وعينته المتمثلة بالمعنيين من حكام واداريين ومدربون بالكرة الطائرة إذ بلغت العينة (185) فرداً، وبعد ذلك أجريت إجراءات البناء واختيار المجالات والعبارات ومن

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على الرغم من إن الابداع والمبدعين وخصائصهم العقلية والشخصية تعد من المفاهيم المهمة والشائعة في الحياة بمجالاتها كافة، ففي الوقت الذي نجد فيه العديد من الدراسات والمقالات العربية والاجنبية التي تناولته بشكل او باخر، لكنها جميعها اعتمدت على المقياس الخاص بالتفكير الابداعي لمؤسسه الاول تورانس منذ عام (1967)، متجاهلة التغيير والتطور المعلوماتي ولا سيما في الانترنيت والحاسوب وما افرزه هذا من مفردات شاعت وتداول