Background: The incisive canal is an anatomical structure with an important location in the anterior maxilla, analyzing this canal and its relation to the bone anterior to the canal is necessary during dental implant. Aim of this study is evaluated effect of gender, age and tooth loss in area of maxillary central incisors teeth on the dimensions of incisive canal and buccal bone anterior to the canal using spiral computed tomography. Materials and Methods: Sample consists of prospective study for 156 subjects for both gender, they divided into two groups, 120 dentate group (60 male and 60 female) with age ranging from (20-70) and 36 edentate group (with missing maxillary central incisors) (18 male and 18 female) with age ranging from (50-70). All subjects attended to Baquba teaching general hospital in Diyala for computed tomography scan investigation for different diagnostic purposes. The following were measured and recorded from sagittal section of CT for analysis 1-diameter and length of incisive canal.2- distance and length of buccal bone anterior to canal. Result: Gender had effect on the dimensions of incisive canal and buccal bones anterior to this canal, the mean values begin higher in male as compared to female. Dental status had effect on incisive canal length and buccal bone dimensions, mean values is higher in dentate than in edentate group, canal diameter remain unchanged with dental status. Age had no effect on all selected measurements in study sample. Duration of maxillary central incisors teeth loss had effect on canal length and buccal bone dimensions mean values begin lower in long duration than that in short duration while it had weak effect on incisive canal diameter. Conclusion: Gender and dental status are important factors that can affect incisive canal and amount of bone anterior to canal.