Background: Impression materials, impression trays, and poured stone cast have been said to be the main source of cross infection between patients and dentists. However, it was observed that disinfection of the impression is not performed systematically in routine dental practice. Disinfection of alginates either by immersion or spray technique was found to cause dimensional inaccuracies, although with proper disinfection of alginates there were small dimensional changes. A variety of fluoride releasing products designed for topical use is currently available. Following their use, varied amount of fluoride is systemically absorbed depending on the fluoride concentration and the manner of its use. The objective of this study was to evaluate the effect of addition (0%, 0.25%,0.5%,1%, 2%, 3%, 4% ) of (NaF) as a self-disinfection to alginate impression material powder and its effect on setting time, tear strength, dimensional change and accuracy of alginate impression materials. Materials and methods: A total No. of (700) specimen were used in this study.These specimens were divided into (5) main groups according to the tests used. Each of the four main groups contain (70) specimen divided into 7 subgroups (ten specimens to be tested for each (7)concentrations which is composed of six percentages of NaFwith alginate powder (0.25%,0.5%,1%, 2%, 3%, 4% )and one for control (0% NaF) , while the fifth group (Microbiological test) contain 420 specimen were divided between Streptococcus mutans and Candida albicans as (120) specimen for each one that was subdivided into three subgroups (specimens taken before impression casting, specimensafter pouring of alginate with stone andspecimens of stone were taken from the casts) in which it contain the same subgroups of the other concentrationsof (NaF) to test its efficacy against (Streptococcus mutans and Candida albicans). Results: Tear strength for all experimental impression materials was greater than those of the control products. There were no statistically significant differences between the dimensional change tests and also reproduction of detail test.With regard to setting time of the impressions, statisticallyreduction were seen between the control and experimental groups of alginate impression materials that contain (NaF). Self-disinfection of alginate impression material containing NaF showed a significant reduction in the count of cell forming unit of microorganisms immediately after impressions were made. Conclusion: In cooperation of specific concentrations of (NaF) as a disinfectant in alginate dental impression produced a significant reduction of contamination, also they caused non-significant effect on dimensional stability, detail reproduction and significant increase in tear strength. Therefore it is recommended as step in preventing cross contamination. Keywords: Alginate, NaF, Candida Albicans, streptococcus mutans.
This study was aimed to extract the effective material from the dry nests of termites and detect its antibacterial activity against some pathogenic bacterial isolates and inhibit synthesis of its biofilm. Termites dry nests were collected and the effective material was extracted then the antibacterial activity was detected using the disc diffusion assay. Results were showed that the extract have antibacterial material from the Termites dry nests, this extract showed antibacterial activity against Gram positive bacteria (Staphylococcus aureus) at (21.5mm) and Gram negative bacteria ( Enterobacter sp. and Pseudomonas aeruginosa) at (26 mm and 20 mm) respectively by inhibiting their growth, as well as its effect on biofilm production o
... Show MoreMetalloendo peptidase is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones, including atrial natriuretic factor, giucagon, enkephalin, substance p, neurotensin, oxytocin, and bradykinin. It is also a major enzyme for the degradation of beta-amyloid. This study aimed to measure enzyme activity and compare it with other biochemical changes in sera patients with diabetic nephropathy. The study included 35 pathological samples of people with diabetic nephropathy, 24 samples from males and 11 samples from females, as well as the same number of healthy people as a comparison group of 15 males, 20 females, with the ages of both groups of patients with diabetic nephropat
... Show MoreGiven the paucity and toxicity of available drugs for leishmaniasis, coupled with the advent of drug resistance, the discovery of new therapies for this neglected tropical disease is recognised as being of the utmost urgency. As such antimicrobial peptides (AMPs) have been proposed as promising compounds against the causative Leishmania species, insect vector-borne protozoan parasites. Here the AMP temporins A, B and 1Sa have been synthesised and screened for activity against Leishmania mexicana insect stage promastigotes and mammalian stage amastigotes, a significant cause of human cutaneous disease. In contrast to previous studies with other species the activity of these AMPs against L. mexicana amastigotes was low. This suggests that ama
... Show MoreThe effect of the aqueous extract of fig (Ficus carica) fruit was studied by using different concentrations of this fruit (15, 20 and 25 mg/kg of body weight) on some hematological parameters (hemoglobin concentration, packed cell volume, white blood cell count and platelets count) in female rabbits. Twenty female rabbits were randomly divided into four groups (five animals in each group). Three groups were dosed with the concentrations mentioned above, while the last was administered with distilled water and considered as control group. These animals were orally dosed by aqueous extract using a micropipette. The results showed that there was a significant (P<0.05) increase in hemoglobin concentration and packed cell volume means for all
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