Background: Impression materials, impression trays, and poured stone cast have been said to be the main source of cross infection between patients and dentists. However, it was observed that disinfection of the impression is not performed systematically in routine dental practice. Disinfection of alginates either by immersion or spray technique was found to cause dimensional inaccuracies, although with proper disinfection of alginates there were small dimensional changes. A variety of fluoride releasing products designed for topical use is currently available. Following their use, varied amount of fluoride is systemically absorbed depending on the fluoride concentration and the manner of its use. The objective of this study was to evaluate the effect of addition (0%, 0.25%,0.5%,1%, 2%, 3%, 4% ) of (NaF) as a self-disinfection to alginate impression material powder and its effect on setting time, tear strength, dimensional change and accuracy of alginate impression materials. Materials and methods: A total No. of (700) specimen were used in this study.These specimens were divided into (5) main groups according to the tests used. Each of the four main groups contain (70) specimen divided into 7 subgroups (ten specimens to be tested for each (7)concentrations which is composed of six percentages of NaFwith alginate powder (0.25%,0.5%,1%, 2%, 3%, 4% )and one for control (0% NaF) , while the fifth group (Microbiological test) contain 420 specimen were divided between Streptococcus mutans and Candida albicans as (120) specimen for each one that was subdivided into three subgroups (specimens taken before impression casting, specimensafter pouring of alginate with stone andspecimens of stone were taken from the casts) in which it contain the same subgroups of the other concentrationsof (NaF) to test its efficacy against (Streptococcus mutans and Candida albicans). Results: Tear strength for all experimental impression materials was greater than those of the control products. There were no statistically significant differences between the dimensional change tests and also reproduction of detail test.With regard to setting time of the impressions, statisticallyreduction were seen between the control and experimental groups of alginate impression materials that contain (NaF). Self-disinfection of alginate impression material containing NaF showed a significant reduction in the count of cell forming unit of microorganisms immediately after impressions were made. Conclusion: In cooperation of specific concentrations of (NaF) as a disinfectant in alginate dental impression produced a significant reduction of contamination, also they caused non-significant effect on dimensional stability, detail reproduction and significant increase in tear strength. Therefore it is recommended as step in preventing cross contamination. Keywords: Alginate, NaF, Candida Albicans, streptococcus mutans.
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Nanosponges (NS) of etodolac(ETO) was prepared using the emulsion solvent diffusion method ; the effects of drug: polymer ratio, the effect of level concentration of internal phase and stirring time and other variables that effect on the physical characteristics of NS were investigated and characterized, The selected formula was lyophilized then incorporated into hydrogel ; which also evaluated .The results show that the formulation that contain Drug: PVA:EC in ratio 1:3:2 is the best with smallest particle size 40.2±0.098 with polydispersibility0.005 and in vitro release 97.6±0.11%, , ETO NS Carbopol hydrogel produced a significant(p<0.05) improvement of the in vitro release than pure ETO hydrogel.
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The rapid increase in the number of older people with Alzheimer’s disease (AD) and other forms of dementia represents one of the major challenges to the health and social care systems because of a large number of people affected. Early detection of AD makes it possible for patients to access appropriate services and to benefit from new treatments and therapies, as and when they become available, and to plan for the future. The onset of AD starts many years before the clinical symptoms become clear. A biomarker that can measure the brain changes in this period would be useful for early diagnosis of AD. Potentially, the electroencephalogram (EEG) can play a valuable role in early detection of AD. Damage caused to the brain due to AD leads t
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This research aimed at recognizing the properties of curricula that fitted to preeminent and talent students. Many types of these curricula were exposed, enrichment curriculum was explained as one of alternatives of available curricula.
The research used the analytical methodology for local and international literature in the field of preeminent and talent education to meet the properties of curricula that fitted to this special group of students. Many results was obtained as:
• This type of school enrichment curriculum consists of three levels( general discovery activities, individual and groups training activities, and individual or groups real problems).
• Investigation the effectively both sides of brain: right and left,
The outstanding evidence of phthalimide pharmacophore in securing enhanced biological activities had encouraged further research and development into phthalimide-based derivatives as potential new drugs. In this study, phthalimide core was hybridized with aldehydes giving integrated imines displaying different types of functionalities and at alternating positions. The resulting compounds, therefore, provide an innovative window to explore possible differential biological effects as antioxidants and anticancer agents. A total of sixteen compounds were synthesized, and each was verified by FT-IR, H NMR, C NMR, and MS characterization. Herein, a facile single-step synthesis method was employed substituting the conventional two-step che
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Objective: The present study was aimed to develop a pH-triggered in situ gel for local release of lidocaine hydrochloride (lidocaine HCL) in the buccal cavity to improve the anesthetic effect of this amino amide drug which has very high water solubility. The formulations were introduced to the oral cavity as a spray to improve compliance and for easier administration.Methods: In this work, two grades of carbopol (934 and 940)-based in situ gel spray were designed. The formulations containing lidocaine HCl 5% were prepared by mixing different concentrations of carbopol with xanthan gum. Eight formulations were investigated and evaluated for gelation capacity, spray angle, volume of solution delivered per each actuation, rheological p
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