Background: The accuracy of fitness of any dental casting is imperative for the success of any prosthodontic treatment. From the time that dental casting was first introduced, efforts have been made to produce more accurate and better fitted castings with minimal marginal discrepancy. The aim of this in vitro study was to evaluate the effects of three different investing and burnout techniques on the vertical marginal discrepancies ofceramometalcopings invested with two types of phosphate- bonded investments. Materials and methods: Sixty wax patterns were fabricated on a standardized prepared brass die representing an upper central incisor by the aid of a custom-made split mold. Three different investing and burnout techniques were applied for an Iraqi investment and a commercial type; Group I:Ring investing with conventional burnout technique (RC);Group II: Ringless investing with conventional burnout technique (RLC);Group III: Ring investing with accelerated burnout technique (RA).Twenty wax patterns of each group were divided into two subgroups according to the type of investment material used (10 for each subgroup) represented as (B) for the BellaStar XL and (W) for the WYMvest investments. Complete castings were finished and seated on the metal die. The accuracy of fit of each coping was determined by measuring the vertical marginal discrepancies between the finish line on the metal die and the margins of each coping at four specific reference points on the labial, mesial, palatal, and distal aspects of the die by the aid of a light microscope supplied with a digital camera.The arithmetic mean of each three records was computed and regarded as the amount of the marginal discrepancy of each coping and was used as a unit for the statistical analysis. Results: Mean marginal accuracy for W(RLC)was found to be the least (13.839+4.5724 um) while the highest mean value related to B(RLC) (29.033+2.102 um). In general, ANOVA test showed significant results among the mean values of the Binvestment subgroups while LSD test showed non-significance between the (RA) and both the (RC) and (RLC) subgroups. On the other hand, significance was present between the (RLC) and (RA)of the Winvestment subgroups while non-significance was located between the (RC) and both the (RLC) and (RA) subgroups. Comparing similar subgroups of the two tested investments, the Student's t-test showed non-significance between the (RC) subgroups while high significance was located between the (RLC) and (RA) subgroups respectively.Concerning the vertical marginal discrepancy of the copings, applying the (RC) technique for both investments caused non-statistical significance between the labial, mesial, palatal, and distal aspects.The (RLC) technique caused high significance between the four aspects, while the (RA) technique caused non-significance between the labial aspect only and the others. Conclusion: The Iraqi investment generally produced less vertical marginal discrepancies (using the three different investing and burn-out techniques) than the commercial investment.In order to achieve a better marginal fit, it seems that ceramometalcopings invested with the commercial investment tested are better be cast using the conventional ring investing and burnout technique.
To determine the association between cigarette smoking and oxidative stress, a study was conducted in the period from January 2020 to April 2021, at College of Medicine, Al-Nahrain University, Baghdad, Iraq. The Enzyme-linked immunosorbent assay (ELISA) technique was utilized for measurement the antioxidant enzymes including: Glutathione superoxide (GPX) and catalase (CAT) and the biomarker of lipid peroxidation Malondialdehyde (MDA). Also, the gene expression of Nrf2 and HO-1were determined by using RT-PCR technique. The results indicate lower level of both GPX and CAT (p ≤ 0.001) in smokers compared with non-smokers. While the result of MDA indicate higher level in smokers (p≤0.001) compared with nonsmokers. The Nrf2 and HO-1 gene exp
... Show MoreThe members of the family of Eentrobacteriaceae harbour a gene cluster called polyketide synthase (pks) island. This cluster is responsible for the synthesis of the genotoxin colibactin that might have an important role in the induction of double-strand DNA breaks, leading to promote human colorectal cancer (CRC). Eleven out of the eighty eight isolates (12.5%) were pks+, distributed as 7 (8%) isolates of E. coli, 2 (2.25%) of K. pneumoniae and 2 (2.25%) of E. aerogenes. The cytotoxic effects of selected pks+ isolates (E. coli and E. aerogenes) on HeLa cells were represented by decreasing cell numbers and enlarged cell nuclei in comparison to the untreated cells. Cytological changes were observed when the infected HeLa cells culture
... Show MoreThe role of transmembrane protease serine 2(TMPRSS2) in prostate carcinogenesis relies on overexpression of ETS transcription factors. The aim of this article was to investigate the association of TMPRSS2 polymorphism (rs12329760 (C\T)) with prostate cancer (PCa) in sample of Iraqi patients. One hundred and two individuals were involved in this study for the period from February – 2019 to February – 2020. The sample type was formalin fixed paraffin embedded tissue samples (FFPE), which involved fifty-six samples of pre-diagnosed patients with prostate cancer, aged between 48 and 86 years, and forty-six samples were found to be controls (healthy group) dependent on Prostate Gland integrity, which is the same age as in a group o
... Show MoreThe current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total of ninety subjects were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM g
... Show MoreThere are a few studies that discuss the medical causes for diabetic foot (DF) ulcerations in Iraq, one of them in Wasit province. The aim of our study was to analyze the medical, therapeutic, and patient risk factors for developing DF ulcerations among diabetic patients in Baghdad, Iraq.