Background: Lymphomas are a group of diseases caused by malignant lymphocytes that accumulate in lymph nodes and cause the characteristic clinical features of lymphadenopathy. Intercellular adhesion molecule-1 (ICAM-1) (CD54) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily of adhesion molecules. Cortactin was first identified as one of the major substrates for src kinase. because it localized to Cortical actin structures, The aims of this study was to evaluate and compare the immunohistochemical of ICAM-1 expression as cell adhesion molecule marker and Cortactin expression as invasive marker. Material and Methods: This study was performed on (68) formalin-fixed, paraffin-embedded blocks, histopathologically diagnosed as lymphoma (head and neck lesions).Immunohistochemical staining of ICAM-1and Cortactin was performed on each case of the study sample. Results: The expression of ICAM-1 was membranous and cytoplasmic, the study cases showed a 98.5% positive reaction to ICAM-1, score 2 was the most common and found in 69.1% of all cases.The expression of Cortactin was cytoplasmic, 98.5% of cases expressed positive reactions to Cortactin, score 1 was the most common and found in 42.7% of all cases. Conclusion: Although the two markers showed a higher expression rate in all lymphomas (both HL and NHL) in this study, they can't be used to differentiate between them, nor can be used to differentiate between the subtypes of both HL and NHL. The high ICAM-1positive expression clarified that in addition to its role in cell-cell and cell-stromal interactions, it participates in proliferation, differentiation and invasion of malignant lymphoma cells.The present study is the first one that used Cortactin as an invasive marker for lymphoma.
The liver is one of the largest glands in the digestive system and performs 13 various functions, including the secretion of hormones and enzymes. The gallbladder serves as a storage reservoir for secretions before they are released into the digestive system through the duodenum. The bile ducts branch from the liver’s lobes and ultimately connect to the digestive system, making this structure significant and distinct among different animal species. This review focuses on the differences between dogs and cats, highlighting the importance of these differences from both health and pathological perspectives. After conducting a detailed scientific review of the biliary tree in dogs and cats, we concluded that cats are more susceptible
... Show MoreIn this paper, we investigate the connection between the hierarchical models and the power prior distribution in quantile regression (QReg). Under specific quantile, we develop an expression for the power parameter ( ) to calibrate the power prior distribution for quantile regression to a corresponding hierarchical model. In addition, we estimate the relation between the and the quantile level via hierarchical model. Our proposed methodology is illustrated with real data example.
Orthodontic wires facilitate the required dental adjustments in the context of orthodontic therapy. The archwire has played a crucial role in orthodontic treatment, and the increasing emphasis on aesthetic preferences from patients, as well as the development of composite and ceramic brackets, have prompted investigations into aesthetic archwires that complement these brackets. Orthodontic wires are produced using a diverse range of materials. The utilisation of all available wire types can improve patient comfort, decrease chairside time, and shorten the overall duration of treatment. The individual clinician must possess comprehensive knowledge and comprehension of the various requirements and alternatives throughout the therapeut
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The anatomical study of the epidermis leaflet for seven species and variety wild belonging to the genus Medicago L. species are: M. constricta Dur., M. coronata L., M. intertexta L., M. intertexta.var. ciliaris L., M. laciniata L., M. lupulina L., M. minima L. and M. sativa L. were studied, The search included epidermis characters and stomatal complexes addition to venation system in leaflets. It is revealed through the study, epidermis leaflet type Amphistomatic (the stomata spread on the upper and lower surface) as well as the presence of three types of stomatal complexes namely: Anisocytic (the guard cells surrounded by three unequal cell size), Anomocytic (not differential from subsidiary cells in epidermis) and Anomotetracytic (four ce
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Of the importance of the concept of ownership of real estate as the basic basis from which various projects are launched in various economic, tourism, and urban areas .... The need to research the diagnosis of real estate reality went astray in the difficulties, which played a decisive role in the process of urban development.
This leads us to the research problem of the difficulty of implementing urban development plans in many cases due to the absence of a clear methodology for organizing and modernizing the ownership of real estate and its coordination with the management of urban land and to achieve the objective
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Morphological and histological study was conducted to examine the structure of prosencephalon (Cerebrum) in Columba oenas (Linnaeus, 1758). Thirteen animals of C. oenas were used in the present study. The brains were excised, fixed and recessed for the preparation of microscope slides and used hematoxylin-eosin stain, methylene blue and Bielschowsky’s stain. The result of morphological study showed that the cerebrum is apportion of the prosencephalon and the largest part of the brain and the dorsal surface was smooth and convex and composed of two cerebral hemispheres. The cerebral hemisphere contains the cavity which called lateral ventricle. The hemispheres were connected by the anterior commissure. Histologyically the cerebral hemisphe
... Show MoreAbstract The present study aimed to investigate the morphological description and histological structure of thyroid gland in Herpestes javanicus . The results revealed that thyroid gland in adult Herpestes javanicus is located in the neck region just below the larynx and attached to the trachea . Histological study revealed that thyroid gland in H. javanicus surrounded by a capsule of losse connective tissue and the thyroid gland mainly formed from follicles within different sizes. The results showed that the follicle consists of three compenets represented by follicular lining cells, basal parafollicular cells and the colloid. Microscopical examination revealed that the follicular lining tissue is either to be simple squamous or simple cub
... Show MoreThe current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total of ninety subjects were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM g
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