Background: It has been well known that the success of mandibular implant- retained overdenture heavily depends on initial stability, retention and long term osseointegration this is might be due to optimal stresses distribution in surrounding bones. Types of mandibular implant- retained overdenture anchorage system and number of dental implants play an important role in stresses distribution at the implant-bone interface. It is necessary to keep the stresses below the physiologic tolerance level of the bone .since. And it is difficult to measure these stresses around bone in vivo. In the present study, finite element analysis used to study the stresses distribution around dental implant supporting Mandible implant retained overdenture Materials and methods: Eight models were constructed including four designs of anchorage system (ball-cup, ball-O Ring, bar without distal extension and bar with distal extension).The first group of models were supported by four dental implant and second group of models were supported by two dental implant only. Models constructed from the data obtained directly from patient The contour of bone was obtained from C.T scan image of patient, then data transferred to ANSYS program for modeling then load applied and solve the equation by the program, Specified nodes were selected at the rings of crestal bone (cortical bone) and cortical cancellous interface around each dental implant and fixed for all models to monitor the stress change in that regions of different design of MIR-OD.. After load application, Specified nodes were selected at the rings of crestal bone (cortical bone) and cortical cancellous interface around each dental implant and fixed for all models to monitor the stress change in that regions of different design of MIR-OD . Results: In the present study the stress distribution and maximum stresses value around dental implant had a relationship to the number of dental implant. , The result appeared that the maximum stresses and means of stresses value was lower in the first group of models (which was supported through the use four dental implant) than the second group of models (which was supported through the use of two dental implant only). For the first group of models the maximum stresses value around mesial implant was11.67, 10.51, 10.98 and 10.72 Mpa, while the maximum stresses around distal implant was 21.33, 18.51, 18.86, and17.56 Mpa for models 1,2,3 and 4respectively ,and the stresses around implant supporting second group of models was 22.52, 22.16, 20.51 and 19.60 Mpa for models 5,6,7and8 respectively .Statistical analyses of means value appeared that there was statistically significant difference in stresses means value around implant of the second group with that’s values around mesial and distal implant supporting first group of model . Regarding the result of both ball and bar system, it has been demonstrated that stress was greater with ball attachment and MIR-OD supported by the use of four dental implants and anchored by bar attachments with distal extension gives the minimum values of stresses than the rest models. Also the results show that higher stresses value was appeared at the cortical bone ring surrounding dental implant especially the distal implant nearest to the free end extension area. Also it was appeared that the best model was Mandible implant- retained overdenture that’s anchored by bar with distal extension and support by four dental implant. Conclusions: Bar-clips with distal extension mode of attachment considered the best type in producing the least stresses around dental implant regardless number of dental implant used.
Checkpoint inhibitors are a type of immune therapy used to treat different types of cancers. These drugs block different checkpoint proteins, for example, CTLA-4, PD-1, and PD-L1 inhibitors.
They block proteins that stop the immune system from attacking the cancer cells. Checkpoints are also described as a type of monoclonal antibody that antagonizes binding between B7 to CTLA-4 and PD-L1 to PD-1.
Immune checkpoint inhibitors are used to treat BARCA mutated triple-negative breast cancer (TNBCS) in patients who do not respond to chemotherapy, and also in the treatment of highly mutated and solid tumors such as brain tumors, liver, and pancreatic cancers.
Immune checkpoint inhibitors exhibit an effect on solid tumo
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Objectives: The study aims to evaluate the effectiveness of the educational program on nurses’ knowledge towards nursing management for patients undergoing percutaneous coronary intervention (PCI), as well as to find out the relationship between nurses' knowledge and some of their demographic characteristics (age, gender, level of education, and years of experience in cardiac units).
Methodology: A Quasi-experimental as one group (pre and post test) study was conducted at the Heart Center in Al-Diwaniyah city for the period from December 7, 2019 to February 23, 2020. A sample of (40) nurses working in the heart center was chosen from different nursing addresses. The sample covered one gro
... Show MoreThe research aims to develop a proposed mechanism for financial reporting on sustainable investment that takes the specificity of these investments.
To achieve this goal, the researcher used (what if scenario) where the future financial statements were prepared for the year 2026, after completion of the sustainable project and operation, as the project requires four years to be completed.
The researcher relied on the results of the researchers collected from various modern sources relevant to the research topic and published on the internet, and the financial data and information obtained to assess the reality of the company's activity and its environmental, social, and economic i
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Semiconductor-based photocatalytic processes are widely applied as ecofriendly technology for degrading organic pollutants. Establishing photocatalytic heterojunctions with Z-type photocarriers transfer pathways is projected to be a superb strategy to enhance photocatalytic behavior. In this paper, novel and stable (0D/2D) heterojunctions of CoS-embedded boron-doped g-C3N4 (CoS/BCN) with a high rate of charges transfer/separation were assembled for degradation of malachite green dye (MG). The CoS/BCN photocatalyst achieves a photodegradation efficiency of 96.9 % within 1 h of LED illumination, which is 2.5 and 1.4-fold enhancement compared with bare g-C3N4 and BCN, respectively. Besides, the results of species-trapping trials exhibited that
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In this research investigation, a total of eighteen diverse tetra- and penta-lateral cyclic compounds were synthesized. These included 1,3,4-thiadiazole, thiazolidin-4-one (via an alternative method), 1,2,4-triazole, carbothioamide, thiazole-4-one, azetidin-2-one, and oxazole. The synthesis procedure entailed a sequence of reactions. The thiazolidine-4-one 1 was obtained by reaction p-aminobenzoic acid with thiosemicarbazide, followed by treatment with p-tolualdehyde to produce Schiff base 2. Reaction Schiff base 2 with mercaptoacetic acid in dry benzene was carried out to produce thiazolidine-4-one 3. In another synthesis pathway, the esterification of p-nitro benzoic acid with ethanol in the presence of sulfuric acid was
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The research aims to determine the impact of employees’ retention strategy on organizational memory. This research is historical, descriptive, and analytical. The sample consists of 158 faculty members in five private colleges in Baghdad. The technique used to analyze the data is SEM (Structural Equation Modeling), and SPSS (Statistical Package for the Social Sciences). The research concludes that the employees retaining strategy plays a vital role in retaining employees and hence maintains organizational memory. The findings and recommendations of this research assure the administrations of private colleges that employees retention strategy play a vital role in retaining its employee and hence maintains organizational memory. T
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