Background: An oily calcium hydroxide formulation proved over the last years to be highly efficient in promoting bone regeneration in closed defects as periapical lesions, cysts, or post-extraction defects. The aim of the present study is the assessment of the outcome of treatment of deep intrabony periodontal defects with an Open Flap Debridement) (OFD) + combination of {(30% Hydroxyapatite HAp + 70% ?-Tricalcium Phosphate granules mixed with an Oily Calcium Hydroxide Suspension (OCHS )} and compare the results with {(OFD) alone)}. The combination of OCHS& TCP was used in humans with a sort of positive results, and more conduction of studies was recommended. Material and method: The sample of this study composed of sixteen patients; each had at least two intrabony defect teeth. For each patient, one tooth was treated by OFD only (control group 16 teeth) and the other teeth (study group 16 teeth) were treated with OFD + a mixture of (OSTEON II- Korea) granules comprise of (30% Hydroxyapatite HAp + 70% ?-Tricalcium Phosphate) and OCHS (Osteoinductal®, Osteoinductal GmbH., Muenchen, Germany). The clinical parameters that were measured and recorded included (Plaque index PLI, Gingival index (GI), Gingival recession(GR) , Bleeding on probing (BOP), probing pocket depth (PPD), clinical attachment level (CAL) and radiographical width & depth of the bony defect. These parameters were recorded before treatment (base line) & six months after the treatment. Results: The results after treatment revealed a highly significant reduction in all of the parameters except the PLI in both study & control groups compared to baseline (p < 0.001). The clinical results were indicated that the study group showed significant reductions of PPD and CAL mean values more than improvements obtained by the control group with significant difference (p < 0.05). Conclusions: An excellent postoperative improvement in clinical parameters was noticed in the study group more than control group and the differences were significant. Thus the present study has revealed that the treatment modality of OFD + a combination of granules comprise of (30% Hydroxyapatite HAp + 70% ?-Tricalcium Phosphate) mixed with oily Calcium Hydroxide suspension is successful, predictable and more beneficial than (open flap debridement) (OFD) alone in the treatment of deep intrabony periodontal defects.
Herein, a biocomposite of crosslinked chitosan polyethylene glycol diglycidyl ether (CS-PEDGE), montmorillonite (MMT), and foodgrade algae (FGA) was successfully prepared by a hydrothermal technique. The resulting absorbent (CS-PEDGE/FGA/MMT) was assessed for its adsorption property with methyl violet 2B (MV 2B) a toxic cationic dye. The physicochemical properties of CS-EDGE/ FGA/MMT were assessed via various analytical techniques, including BET, Elemental analysis, pHpzc, and spectroscopy (FTIR, XRD, SEM-EDX). The influence of three adsorption variables, namely adsorbent dose (A: 0.02–0.1 g/100 mL), solution pH (B: 4–10), and contact time (C: 10–420 min) on the rate of MV 2B dye removal was examined using the Box-Behnken design (RSM-
... Show MoreWellbore instability problems cause nonproductive time, especially during drilling operations in the shale formations. These problems include stuck pipe, caving, lost circulation, and the tight hole, requiring more time to treat and therefore additional costs. The extensive hole collapse problem is considered one of the main challenges experienced when drilling in the Zubair shale formation. In turn, it is caused by nonproductive time and increasing well drilling expenditure. In this study, geomechanical modeling was used to determine a suitable mud weight window to overpass these problems and improve drilling performance for well development. Three failure criteria, including Mohr–Coulomb, modifie
Sequencing technologies have reshaped the study of the subgingival microbiome, but selecting the appropriate method remains challenging because of differences in resolution, cost, host DNA contamination, and computational complexity. This review compares 16S rRNA sequencing, full-length 16S, shotgun metagenomics, and metatranscriptomics with respect to taxonomic resolution, functional output, sample requirements, and analytical limitations. Key practical issues, including low microbial biomass, contamination control, and the choice of appropriate bioinformatic tools, are emphasized to help researchers avoid common pitfalls. A decision-making framework is provided to link study goals to suitable sequencing methods while outlining rea
... Show MoreObjective: Synthesized a series of new thiourea (TU) derivatives, tested their antioxidant activity, and investigated their expected biological activity by theoretical study (computational methods). Methods: The derivatives were made using a one-pot reaction with two steps. Initially, succinyl chloride was mixed with KSCN to make succinyl isothiocyanate. Then, primary and secondary amines were used to make TU derivatives. The theoretical studies were done by Swiss ADME and molecular docking via Genetic Optimization of Linkage Docking (GOLD). Then evaluate antioxidant activity using the DPPH scavenging method. Results: FT-IR, 1H NMR, and 13C NMR spectroscopy show the verification of all the prepared derivatives. Compounds (II), (VIII),
... Show MoreThis study refers to the development and characterization of silver oxide nanoparticles obtained by X-ray diffraction, nanostructured silver oxide was used in order to calculate the micro strain and crystal size by Halder-Wagner method and by relying on X-ray diffraction diagram of the nonstructural silver oxide, where the results of the crystal size and the micro-strain were 4nm and 0.33 respectively. Other analysis techniques, such as the Size-strain plot, The X-ray diffraction study confirmed that the crystalline nature of silver oxide nanoparticles has a cubic structure. Through the X-ray diffraction results, the crystal size was calculated using Debye-Scherrer and Williamson-Hall methods. Halder-Wagner (HW), Size-strain plot, D
... Show MoreIn this article the nanoparticles synthesis of ZnO (Nps) by using the precipitation method at concentrations range (0.5, 0.25, 0.125, 0.0625, 0.03125) mg/mL and then activity was examined against Streptococcus spp that causing dental caries in vitro by well diffusion method, find these concentrations effected in these bacteria and better concentration is 0.03125. ZnO Nps were characterization by EDS to prove this particles are ZnO, and also characterized by atomic force microscope (AFM), X-ray Diffraction (XRD) and TEM, from these technic found that the average size about 30.52 nm and hexagonal shape. The UV-visible result reveals that the large band is observed at 340.8 nm, Zeta potential show that the surface charge is 30.19 mv an
... Show MoreThe ability of the human brain to communicate with its environment has become a reality through the use of a Brain-Computer Interface (BCI)-based mechanism. Electroencephalography (EEG) has gained popularity as a non-invasive way of brain connection. Traditionally, the devices were used in clinical settings to detect various brain diseases. However, as technology advances, companies such as Emotiv and NeuroSky are developing low-cost, easily portable EEG-based consumer-grade devices that can be used in various application domains such as gaming, education. This article discusses the parts in which the EEG has been applied and how it has proven beneficial for those with severe motor disorders, rehabilitation, and as a form of communi
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