Background: Mouth breathing can lead to introduce cold, dry unprepared air that insults the tissue of oral cavity, nasopharynx and lung, leading in turn to pathological changes in oronasal cavity, nasopharyngeal and other respiratory tissue, mouth breathing associated with nasal obstruction may lead to many health problems, in particular oral health problems such as inflammation of gingiva, oral dryness, change in oral environment that may decrease pH, salivary flow rate and increase bacteria and dental caries.Aims of the present study were to assess the oral health condition among mouth breather associated with nasal obstruction, including dental caries, oral cleanliness and gingival health condition as well as to evaluate the changes in salivary physical characteristics and salivary mutans streptococci counts, and their relation to oral variables in comparison to a control group. Materials and Methods: Thirty patients with mouth breathing associated with nasal obstruction (15 females and 15 males) were selected as a study group with an age range (18-22) years old, all subjects were examined by ENT specialist to confirm mouth breathing. A 30 gender and age matched healthy looking subjects without nasal obstruction were selected as control. The diagnosis and recording of dental caries was according to severity of dental caries lesion through the application of D1_4MFS(Manji et al., 1989). Plaque index of (Silness and Loe, 1964) was used for plaque assessment; gingival index of (Loe and Silness, 1963) was used for gingival health condition assessment. Stimulated salivary samples were collected according to (Tenovuo and Lagerlof, 1996) and the following variables were recorded: microbiological analysis included the salivary counts of mutans streptococci, salivary flow rate, salivary pH (potential of hydrogen) and then measurement of salivary viscosity by using Ostwald's viscometer. Results: Results of the present study showed that the mouth breathing group had statistically highly significant, higher plaque and gingival indices than nose breathing group (P<0.01) with a positive highly significant correlation between them in mouth breathing and nose breathing groups (r=0.56, r= 0.64, respectively).The salivary flow rate was lower among mouth breathing with highly significant difference than nose breathing (P<0.01), also salivary pH was lower among mouth breathing but with significant differencecompare to nose breathing (P<0.05); statistically a negative highly significant correlation was recorded among mouth breathing group between salivary flow rate with gingival index (r= -0.56). It has been found that salivary viscosity was not statistically significant difference between mouth breathing group and nose breathing group. The salivary viscosity was found to be inversely significantly correlated with salivary flow rate among mouth breathing group (r= -0.38). While it was positively not significantly correlated with plaque index, gingival index and counts of mutans streptococci among mouth breathing group. Data analysis of the present study showed that salivary mutans streptococci counts among mouth breathing group were higher than that among nose breathing group, difference was statistically highly significant (P<0.01). Conclusion: Mouth breathing associated with nasal obstruction may have an effect on oral health status, leading to an increase in periodontal disease and changes in dental caries.
Background: Myasthenia gravis is an autoimmune disease of the neuromuscular junction that results in fluctuating muscle weakness as well as significant fatigue. Disease exacerbation is a critical condition, and the predisposing factors for it need to be identified to improve preventive measures.
Objectives: Our study aims to determine the predisposing factors for myasthenia gravis exacerbations in a group of Iraqi patients.
Subjects and Methods: A total number of 30 myasthenia gravis patients were admitted to the hospital with an exacerbation of their symptoms, determined as the development of functional disability, dysphagia, or respiratory fai
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Background: Nutrition can affect periodontal disease through contributing to microbial growth in the gingival crevice, affecting the immunological response to bacterial antigens and assisting the repair mechanism of the connective tissue at the local site after injury from plaque and calculus. The aim of this study was to assess the prevalence of Oral hygiene (plaque and calculus) and gingivitis in relation to age, gender and nutritional status. Materials and methods: The sample included (444) kindergarten children at age of (4 and 5 years old) males and females from urban areas in Al-Ramadi city. The assessment of nutritional status was performed using anthropometr
... Show MoreBackground: Dental caries is the most common oral problem, although dental caries is not life threating, it has aharmful effect on quality of life. Socioeconomic factors were found to be strong predictors of the prevalence of oral diseases in children, likes family income, occupational prestige, and education. The aim of this study is to assess the effect of socioeconomic factors on occurrence dental caries in their children. Materials and methods: The sample consists of 550 kindergartens children aged between (4-5) years were selected randomly, girls and boys. The kindergartens selection was randomly from different geographical areas in Al-Najaf governorate. Information was taken from children's parents using questionnaire with the help o
... Show MoreAssessment of Salivary Macrophage Inflammatory Protein-1 Alpha Level in Different Stages of Periodontitis, Riyam Muthanna Muhammed*, Hadeel Mazin Akram
Background: Periodontitis is an infection attributable to multiple infectious; it causes an interrelated cellular and humoral host immune responses. Recent reports have indicated that human cytomegalovirus (HCMV) may contribute to pathogenesis of periodontitis. The HCMV can stimulate the release of cytokines from inflammatory and non-inflammatory cells and weaken the periodontal immune defense. This study aimed to reveal the presence of anti-CMV IgG, and determine the levels of ILâ€6 and TNF-α and to correlate the presence of cytomegalovirus (CMV) with cytokines levels. Materials and Methods: Forty patients with chronic periodontitis and 40 healthy control subjects (their age and sex were matched with the patients) were involved
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For the graph , the behavior associated with to the majority of the graphical properties of this graph is covered in this article. The reflection of the capabilities of on the Ly constructions is one of the key ideas addressed throughout this paper. For instance, by this technique we can comprehend the mechanism via which groups of relatively tiny structure are exist within Ly.
Delivering therapeutic agents to the brain remains a major challenge due to the restrictive nature of the blood–brain barrier (BBB). Intranasal administration has emerged as a promising, non-invasive approach that bypasses the BBB and facilitates direct nose-to-brain transport via the olfactory and trigeminal pathways. In this study, we developed a nanostructured lipid carrier (NLC) system for the intranasal delivery of dolutegravir sodium, a potent integrase inhibitor, with the goal of enhancing brain bioavailability for the treatment of neuroHIV and related central nervous system (CNS) complications. The NLCs were optimized for particle size, polydispersity index (PDI), and drug incorporation efficiency. The optimized formulation exhibi
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الخلفية: التهاب المفاصل الرَثَيَانِي أو الداء الرثياني أو الالتهاب المفصلي الروماتويدي هو مرض مزمن، من الأمراض الانضدادية التي تؤدي بالجهاز المناعي لمهاجمة المفاصل، مسببة التهابات وتدميرًا لها. ومن الممكن أيضًا أن يدمر جهاز المناعة أعضاء أخرى في الجسم مثل الرئتين والجلد. وفي بعض الحالات، يسبب المرض الإعاقة، مؤدية إلى فقدان القدرة على الحركة والإنتاجية. ويتم تشخيص المرض بواسطة تحاليل دم مخبرية مثل تحلي
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