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Salivary Free Testosterone and Gingival Health Condition among a Group of Women with Polycystic Ovary Syndrome
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ABSTRACT Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women in their reproductive age.It is characterized by anovulation or oligo-ovulation and hyperandrogensim.Androgen excess is the central defect in polycystic ovary syndrome. It is a complex disorder affects general health in addition to oral health.This study aimed to assess the gingival health status among a group of women with polycystic ovary syndrome as well as to estimate the levels of salivaryfree testosterone in unstimulated saliva in relation to gingival health condition. Materials and methods: Sixty two women with an age range 20-25 years old and with a body mass index range18.5-24.9 (normal weight) were included in this study. They were divided into two groups; the study group which included thirty one women with polycystic ovary syndrome, those women. nattended Babylon Teaching Hospital/ Infertility Center and the control group which included thirty one women with regular menstrual cycles,without clinical or biochemical features of hyperandrogenism and ultrasound exclusion of polycystic ovary (without polycystic ovary syndrome). Collection of unstimulated salivary samples was carried out under standardrizedconditions, salivary free testosterone levels were estimated. Plaque index of Silness and Lӧe (1964) was used to assess dental plaque. While gingival index of Lӧe and Silness (1963) was used to assess gingival inflammation. Data analysis was conducted through the application of the (SPSS version 18). The analysis of data included: Mean, Standard deviation, t-test, Pearson Correlation (r), Receiver Operative Characteristics Curve (ROC curve). Results:Results showed that the mean value of plaque index was found to be higher in the control group (1.18±0.03) than that in the study group (1.00±0.08) with statistically highly significant difference (p<0.01).While the mean value of gingival indexwas higher among the study group (1.52±0.06)than that in the control group (1.31±0.05)with statistically highly significant difference (p<0.01).Salivary levels of free testosterone among women with polycystic ovary syndrome (44.12±1.37 pg/ml) were found to be higher than that of control (18.50±0.87) with statistically highly significant difference (p<0.01).The results in this study showed that the correlations between salivary free testosterone with the oral variables (plaque index, gingival index) were statistically not significant (P>0.05). In order to assess the specificity and sensitivity of the use of salivary free testosterone as a diagnostic tool, statistical analysis of Receiver Operative Characteristics Curve (ROC) was used and predictive Value Measurmentswere done in this study. The results showed that the area under the curve for salivary free testosterone test was (1.000) with highly significant p-value (p<0.01). The best optimal cut off point for salivary free testosterone was (30.86) with (100%) sensitivity and specificity, indicating a very good predictive capacity for using salivary free testosterone as a marker for the diagnosis of polycystic ovary syndrome. Conclusions : It was concluded that gingival inflammation was high among women with polycystic ovary syndrome. Furthermore, salivary levels of free testosterone were found to be high among women with polycystic ovary syndrome.

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Publication Date
Sun Jul 21 2024
Journal Name
Al-rafidain Journal Of Medical Sciences ( Issn 2789-3219 )
Assessment of the Knowledge and Practice on Safe Handling of Anticancer Drugs among Pharmacists in Iraqi Healthcare Settings
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Background: Occupational exposure to hazardous drugs occurs in all aspects of anticancer drug handling. Proper recommendations and guidelines should be applied to control and reduce exposure. Objective: To assess pharmacists' knowledge and practice regarding the safe handling of anticancer drugs. Methods: A cross-sectional study was conducted at seven major hospitals in Baghdad City, Iraq, from December 2023 to February 2024. A pre-designed questionnaire was given to pharmacists who handled anticancer drugs in chemotherapy units. The questionnaire comprises sociodemographic data, knowledge of the safe handling of cytotoxic drugs and thoughts about exposure and risk, practices for safely handling cytotoxic drugs, and challenges for s

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Publication Date
Thu Nov 21 2024
Journal Name
F1000research
Comparison of the severity of urinary tract infections between Metformin and SGL2 Inhibitors among Iraqi Type 2 Diabetics.
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Background Many antidiabetic medications with distinct modes of action are available, The sodium glucose cotransporter-2 (SGLT-2) inhibitors are among the most recent oral antihyperglycemic medications. The American Diabetes Association recommends metformin, a biguanide medication, as the first option for oral control of type 2 diabetes because it has demonstrated promise in this regard. Aim of the study To evaluate and compare the effects of metformin and SGLT-2 inhibitors on general urine parameters in T2DM patients from Iraq. Method a prospective cohort study where 101 adult patients of both sexes aged under 70 years and newly diagnosed with T2DM, patients were divided into two groups, Metformin group (n=52), where metformin was p

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Publication Date
Wed May 12 2021
Journal Name
Annals Of The Romanian Society For Cell Biology
Cognitive Motivation among Students of the Faculty of Education and its Relationship to the Trend to Teaching Profession
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The present research aims to identify thecorrelation between cognitive motivation andthe trend towards the teaching profession among students of the Department of Chemistry in theFaculty of Education for Pure Sciences - Ibn al-Haytham, as well as to identify the differences in the relationship according to the variable type (male, female). The measures of cognitive motivation and the trend towards the teaching profession were applied, using pearson's correlation coefficient,t-testfor one sample, andthe t-test of two separate samples.

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Publication Date
Sun Oct 01 2017
Journal Name
Journal Of Mechanical Science And Technology
Optimization of a rectangular pin fin using elliptical perforations with different inclination angles
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Publication Date
Tue Feb 01 2011
Journal Name
Biochemical Engineering Journal
Elicitation of Streptomyces coelicolor with E. coli in a bioreactor enhances undecylprodigiosin production
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Publication Date
Thu Sep 01 2016
Journal Name
Applied Thermal Engineering
Solidification of a PCM with nanoparticles in triplex-tube thermal energy storage system
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Publication Date
Thu Sep 07 2023
Journal Name
Journal Of Language Studies
A Sociolinguistic Study of Selected Iraqi-Arabic Dialects with Reference to TV Series
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The dramatic series on television have a great impact on people’sattitudes towards dialects of language varieties, by relating theconceptual pictures or prototypes presented by series’ characters tothose dialects. This study aims to show the influence of TV series onIraqi university learners’ gender and age in relating positive ornegative semantic qualities to their dialects. To this end, 150 Iraqi EFLlearners have participated in this study to examine their attitudestowards Baghdadi, Mousli and Nasiriya dialects. The data arecollected by Lambert, Hodgson, Gardner, Fillenbaum's (1960)matched guise technique and then labeled by Willmorth’s (1988)subjective reaction test. A structured interview is conducted to supportthe data

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Publication Date
Sat Apr 15 2023
Journal Name
Journal Of Robotics
A New Proposed Hybrid Learning Approach with Features for Extraction of Image Classification
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Image classification is the process of finding common features in images from various classes and applying them to categorize and label them. The main problem of the image classification process is the abundance of images, the high complexity of the data, and the shortage of labeled data, presenting the key obstacles in image classification. The cornerstone of image classification is evaluating the convolutional features retrieved from deep learning models and training them with machine learning classifiers. This study proposes a new approach of “hybrid learning” by combining deep learning with machine learning for image classification based on convolutional feature extraction using the VGG-16 deep learning model and seven class

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Publication Date
Fri Dec 08 2023
Journal Name
Frontiers In Endocrinology
Estrobolome dysregulation is associated with altered immunometabolism in a mouse model of endometriosis
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Introduction

Endometriosis is a painful disease that affects around 5% of women of reproductive age. In endometriosis, ectopic endometrial cells or seeded endometrial debris grow in abnormal locations including the peritoneal cavity. Common manifestations of endometriosis include dyspareunia, dysmenorrhea, chronic pelvic pain and often infertility and symptomatic relief or surgical removal are mainstays of treatment. Endometriosis both promotes and responds to estrogen imbalance, leading to intestinal bacterial estrobolome dysregulation and a subsequent induction of inflammation.

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In the current study, we investigated the linkage be

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Publication Date
Thu Jun 29 2023
Journal Name
International Journal Of Nonlinear Analysis And Applications (ijnaa)
Applying a suitable approximate-simulation technique of an epidemic model with random parameters
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Because the Coronavirus epidemic spread in Iraq, the COVID-19 epidemic of people quarantined due to infection is our application in this work. The numerical simulation methods used in this research are more suitable than other analytical and numerical methods because they solve random systems. Since the Covid-19 epidemic system has random variables coefficients, these methods are used. Suitable numerical simulation methods have been applied to solve the COVID-19 epidemic model in Iraq. The analytical results of the Variation iteration method (VIM) are executed to compare the results. One numerical method which is the Finite difference method (FD) has been used to solve the Coronavirus model and for comparison purposes. The numerical simulat

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