ABSTRACT Background: work-related musculoskeletal disorders represent an important occupational health issues among dentists especially neck and low back complaints. Biomarkers of tissue damage as results of occupational physical demands could be used for detection of work related musculoskeletal disorders. Aim: The aim of this study was to assess work- related musculoskeletal disorders, physical work load index, selected salivary biomarkers (Creatine kinase and C - reactive protein) and to find the relation among them. Subjects and Methods: Study participants are consisted of 112 dentists. They were selected from college of dentistry /Baghdad University, health care center in Bagdad city. They were of both gender and aged between 40-45 years .they should fit the study criteria. Self-administered standardized Nordic questionnaires were used to evaluate musculoskeletal complaints. Physical work load was evaluated by used physical work load index. Stimulated saliva were collected from subsample (87) dentists drawn randomly from the total sample, for whom biochemical analysis (measurement of creatine kinase and C - reactive protein) were done. Results: Results showed that low back and neck complaints is the most complaint experienced by the dentists with percentages of ( 69.6% and 66.1% ), followed by the shoulder complaint (49.1% ) while the hip complaint showed the lowest percentage (13.4%).According to severity scores ,both low back and neck musculoskeletal complaints were of score 3 severity (score 3 constituted the highest percentages in both area (27.7% ,23.2%respectively) as compared to other severity scors.For shoulder complaint it was of score 2 severity (score 2 constituted the highest percentage 23.2% as compared to other severity scores, The musculoskeletal complaints(proximal ,neck, shoulder and low back) had higher mean rank values in the highest quartile of Physical work load index with non – significant differences (P<0.05). Regarding salivary creatine kinase the proximal ,total and low back complaints had higher mean rank values among dentists with highest Creatine kinase quartile , while distal manifestations ,neck and shoulder complaints had higher mean rank value in the average interquartile range of Creatine kinase with non – significant differences( P<0.05). For c- reactive protein almost all the complaints(proximal , total ,neck and shoulder) had higher mean rank values in the first lowest quartile with non – significant differences( P<0.05). Conclusions: Physical work load increase the risk of musculoskeletal disorders occurrence. Salivary creatine kinase could serve as a biomarker that reflects the underlying of musculoskeletal complaints more than C - reactive protein. Further studies that used more objective tools for assessing musculoskeletal disorders is needed.
Background: With the start of the current century, increased the interest in the role of the adipose tissue derived substances that named adipokines in the inflammatory diseases of the human being including the inflammatory periodontal disease, but scientific evidences were not clearly demonstrate the association between these adipokines and periodontal pathologies. Materials and Methods: Forty two subjects male only with normal body mass index were selected for the study with an age ranged (30-39 years). Samples were divided into three groups of 14 subjects in each group based on clinical periodontal parameters; clinically healthy gingiva (group I), gingivitis group (group II) and chronic periodontitis patients group (group III), from whom
... Show MoreBackground: Salivary biomarkers, a non-invasive alternative method to serum and tissue based biomarkers and it is consider as an effective modality for early diagnosis. Salivary microRNA 21, a nucleotide biomarker, was reported to increase in patients with oral squamous cell carcinoma. This study was conducted to measure the fold change of microRNA 21 in stimulated saliva and to study its association with smoking and occurrence of oral squamous cell carcinoma. Materials and methods: A 20 patients with oral squamous cell carcinoma who used to be smokers was included in addition to 40 control subjects (20 smokers and 20 non- smokers health looking subjects). Stimulated saliva was collected under standardized condition. Salivary microRNA 21 wa
... Show MoreResearch Summary
... Show MoreThe Behavioral Disorders of Primary School pupils the son of Alcohol and Non Alcoholic
Abstract:
The aim of the current study was to investigate the possible protective effect of graded doses (5, 10, and 15mg/kg) of pyridoxine hydrochloride intraperitoneally injected against (15mg/kg) doxorubicin-induced cardiotoxicity in female rats. Fifty-six (56) Wistar albino female rats were utilized weighing 180-200 gm allocated into eight groups, seven rats each; Group I: negative control distilled water; Group II: Pyridoxine (5mg/kg); Group III: Pyridoxine (10mg/kg); Group IV: Pyridoxine (15mg/kg); Group V: doxorubicin (15 mg/kg); Group VI: Pyridoxine (5 mg/kg) prior to
... Show MoreBackground: While two-thirds of breast cancers express hormone receptors for either estrogen (ER) and/or progesterone (PR) , genetically altered PI3K pathway was found in more than 70% of ER-positive breast cancers.An aberrant activity of cyclin-dependent kinase 1 (CDK1) in a wide variety of human cancers has selectively constituted an attractive pharmacological targets in MYC-dependent human breast cancer cells.
Aim of the study: Role of p110-beta as well as and CDK 1 in the pathogenesis of subset of breast cancers and contribution in their carcinogenesis.
Type of the study: is a retrospective study
Methods: This retr
... Show MoreThe research aims to extrapolate the repercussions of the use of expert systems in the work of the external auditor on the quality of audit, as the research problem was that despite the use of these techniques in audit work, there is a problem related to the efficiency and effectiveness of these technological systems used in audit work, the feasibility of their use and the extent of their impact: The quality of the audit process.
The researchers adopted the questionnaire as a tool for collecting study data from a community composed of auditors in auditing offices and companies in Iraq, and the auditors of the Iraqi Federal Financial Supervision Bureau. The number of recovered and valid qu
... Show MoreThe aim of the research is to identify the attitudes of Iraqi youth
towards volunteering work by using the survey method and the scale
tool to identify what young volunteers can carry from the attitudes
towards volunteering work because the phenomenon of volunteer
work is of great importance in society. The scale was applied to
(525) volunteers among Iraqi youth. The research reached a set
of results, the most prominent of which is the existence of positive
trends among young people towards volunteering work, meaning
that Iraqi youth volunteers have awareness of the concept of
volunteering correctly. As for their goals of volunteering, they are
humanitarian and social goals for the advancement of society, an