Background: The outlook for patients with stomach cancer is generally poor, with gastric cancer being the second most common cause of cancer death. Although advances in diagnosis and treatment have led to a drastic decrease in the incidence of gastric cancer in developed countries in the past few decades. Aim: Our current study aims to evaluate the clinical and pathological outcomes associated with the effect of H. pylori on gastritis (gastric cancer) patients. Methods: To evaluate the association between gastritis (gastric cancer) and H. pylori, demographic and diagnostic parameters of 103 patients were recorded during the follow-up period, which ranged from October 2023 to October 2024, In several hospitals in Iraq. Our study detected the degree and severity of H. pylori by polymerase chain reaction. The quality of life of patients was assessed by a general health assessment (SF - 36) questionnaire, and a curve was made to show the survival rate of patients during the follow-up period. Results: Our outcomes found patients with ages above 45 years were the most group participated, with 42.72%, males with 62 cases and females with 41 cases, obesity with 42.72%, smokers with 36.89%, and alcohol consumption with 12.62%. According of gastric cancer, the upper tumor got 40.78%, tumor size had 6.12 ± 1.42, lymph node metastasis of N1 was 32.04%, N3 was 11.65%, and N2 was 18.45%. Clinical of tumor signs were CEA ?6 ?g/L include 86.41%. Conclusion: Based on our outcomes, gastric cancer remains a large global health problem because H. pylori implicates it as a major risk factor for it