Objective : To study the effect of some risk factors like age, smoking and Diabetes mellitus (DM) among patients with
certain cardiovascular diseases (Angina pectoris and Myocardial infarction), in addition to the assessment of the Creactive
protein (CRP) in the sera of those patients.
Methodology: The study was carried out on (100) subjects who were hospitalized in the Iraqi Center of heart Diseases
in Baghdad city and were suffering from Myocardial InfarcƟon (MI) (16) and Angina Pectoris (AP) (79) or from both (5)
over a period from September 2009 to June 2010. The results of paƟents were compared with those of (30) healthy
and age-matched individuals as a control group. Data were obtained from patients who were already diagnosed by
specialists through the use of questionnaire forms including information about age, gender and smoking. Venous
blood samples were collected from both the patients and control group to estimate the levels of blood glucose and Creactive
protein.
Results: StaƟsƟcal results showed that the majority of angina paƟents were males within the age group (51-60) years
with significant differences between males and females. The study also demonstrated that the incidence of (MI) and
(AP) was higher among non-smokers in comparison with smokers. The study indicated that the majority of patients
with (MI) and (AP) were diabetic. Finally, the study showed that the levels of C-reactive protein among (MI) and (AP)
patients were higher than its level among the control group with a highly significant difference.
Recommendations: A large size of sample is recommended to be studied to confirm the results of this study. Study of
other factors such as hypertension, body mass index and lipid profile may be of value.
Type 2 diabetes mellitus (T2DM) is a chronic disorder that is associated with the imbalance of trace elements which are involved in many functions especially enzyme activities. Changes in the levels of serum elements probably can create some complications in type 2 diabetes mellitus. Previous experimental and clinical studies report that oxidative stress plays a major role in the pathogenesis and development of (T2DM). However, the exact mechanism of oxidative stress could contribute to and accelerate the development of (T2DM).
The aim of this study contained the following sections: firstly, to determine some biochemical parameters in subjects with type 2 diabetes mellitus (T2DM) like lipid peroxidation marker, malondialdeh
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