Objective(s): Ramadan is the Holy month of the Muslims, where they are required to abstain from food and drinks
from dawn till the beginning of night. This study was conducted in Ramadan to investigate the effect of fasting on
hematological incidences, lipid profile, renal and liver function tests among healthy adult males.
Methodology: The present study was carried out in Ramadan – 1431 of Higira (August-September 2010). The study
sample was 56 healthy adult males. Five samples of blood were taken at five intervals (Before, at day 1, 15, 28 and
after Ramadan). Estimation was done for hematological markers, (hemoglobin, white blood cells count, platelet
count); renal function tests (blood urea, serum uric acid, serum albumin, total serum protein); biochemical
parameters, (blood glucose, total serum cholesterol, serum triacylglyceride, high and low density lipoproteins) and
liver function tests (AST, ALT, Alkaline phosphatase, total serum bilirubin).
Results: The mean age of the subjects was 48.4 years (SD 7.15) and mean weight was 79.92 kg (SD 7.94). No
significant changes were observed in weight, hemoglobin, white blood cell count and platelets count, blood urea and
serum albumin values. Whereas, serum uric acid and total serum protein levels were statistically lower during and
aŌer Ramadan (P< 0.05, 0.01).
Blood levels of glucose showed no significant decrease and serum cholesterol and serum triacylglyceride results were
non-significant at first 2 weeks of Ramadan.
The same significant changes (p< 0.05, 0.01) were observed in the lipoprotein at day 15 and 28 of Ramadan. Findings
of liver functions levels showed significant changes. While, total serum bilirubin still with no significant changes during
Ramadan.
Recommendations: The present study recommends performing more studies with both larger groups and in various
categories of healthy and unhealthy subjects.
In The Name of Allah Most Gracious Most Merciful
Scholars, past and present, have paid attention to the books of Fasting and Hajj, and they have compiled literature on that, and they have written treatises and researches. The best days, and as for the pilgrimage, it is one of the great pillars of Islam, which God Almighty has distinguished by making its rituals in the best of places, which is the Sacred House of God.
Background: Oral Lichen planus (OLP) is a T-cell mediated chronic inflammatory oral mucosal disease of unknown etiology. Recent studies have reported an increased oxidative stress and lipid peroxidation in such patients. This suggests that reactive oxygen species may have a role in the pathogenesis of lichen planus. Oxidative stress in OLP release molecules consisting of granzymes resulting in local tissue damage in the effectors. Antioxidants that can defend against oxidative stress in the body cells include enzymes, as well as non- enzymatic antioxidants, such as melatonin, uric acid, vitamin A and E. Purpose: To study the level of salivary vitamin E and uric acid as antioxidant agents in patients with OLP and compared with healthy con
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