Objective(s): Ramadan is the Holy month of the Muslims, where they are required to abstain from food and drinks
from dawn till the beginning of night. This study was conducted in Ramadan to investigate the effect of fasting on
hematological incidences, lipid profile, renal and liver function tests among healthy adult males.
Methodology: The present study was carried out in Ramadan – 1431 of Higira (August-September 2010). The study
sample was 56 healthy adult males. Five samples of blood were taken at five intervals (Before, at day 1, 15, 28 and
after Ramadan). Estimation was done for hematological markers, (hemoglobin, white blood cells count, platelet
count); renal function tests (blood urea, serum uric acid, serum albumin, total serum protein); biochemical
parameters, (blood glucose, total serum cholesterol, serum triacylglyceride, high and low density lipoproteins) and
liver function tests (AST, ALT, Alkaline phosphatase, total serum bilirubin).
Results: The mean age of the subjects was 48.4 years (SD 7.15) and mean weight was 79.92 kg (SD 7.94). No
significant changes were observed in weight, hemoglobin, white blood cell count and platelets count, blood urea and
serum albumin values. Whereas, serum uric acid and total serum protein levels were statistically lower during and
aŌer Ramadan (P< 0.05, 0.01).
Blood levels of glucose showed no significant decrease and serum cholesterol and serum triacylglyceride results were
non-significant at first 2 weeks of Ramadan.
The same significant changes (p< 0.05, 0.01) were observed in the lipoprotein at day 15 and 28 of Ramadan. Findings
of liver functions levels showed significant changes. While, total serum bilirubin still with no significant changes during
Ramadan.
Recommendations: The present study recommends performing more studies with both larger groups and in various
categories of healthy and unhealthy subjects.
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... Show MoreTherapeutic contact lenses TCLs is an approach used to enhance corneal residence time and reduce frequent instillation, which is a problem with eye drops. The problem with CLs is loading of hydrophobic drugs. In this research the CLs were prepared with molecular imprinting MI to enhance the loading of itraconazole, which is used as antifungal drug for fungal keratitis. CLs using different concentration of hydroxyethyl methacrylate HEMA and methacrylic acid MAA were prepared with and without MI using PEGDA (25 μL) and AIBN (37 mg) as crosslinker and initiator respectively. All the prepared CLs were clear and have good folding endurance. MICLs had significantly higher drug loading compared to conventional CLs. The release of i
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