Many conservative sphincter-preserving procedures had been described to be effective in
healing of anal fistula without excision or de roofing.
Objective: To verify the outcome of mere photocoagulation of the fistula tract on healing of low anal
fistula.
Materials and Methods: Using 810nm diode laser, the tracts of low anal fistulae in a cohorts of six male
patients (mean age of 32 yr) had been photocoagulated by retrograde application of laser light through an
orb tip optical fiber threaded in to the tract. Swabs for culture and sensitivity testing were obtained before
and after laser application. Patients were followed up regularly to announce fistula healing.
Results: Mean laser exposure time was 6.6 min., mean operative time was 19 min., mean hospital stay
was 5.9 hrs and mean fistula closure time was 7.7 days. The negative immediate post laser exposure
swabs indicate that laser may have a bacteria killing power. There were no evidences of incontinence or
recurrence within the mean follow up period of 9 weeks. The feasibility of using the selected laser and
accessory was excellent. The basic laser-tissue interaction was thermal photocoagulation without
carbonization.
Conclusions and Recommendations: Mere photocoagulation of the fistula tract may heal a low anal
fistula. Within the chosen parameters of laser application, there was no evidence of damage to the anal
sphincter. It is recommended that larger number of cases to be done to allow for proper statistical
analysis. High, complicated, and recurrent cases may be included. A longer follow up period to assess
intermediate and long term recurrences is recommended.
This work include synthesized and characterization the compound [I] by reaction 1,4-phenylenediamine with chloro acetic acid then this compound reaction with methanol in present sulfuric acid to synthesized ester compound [II] after that reaction with hydrazine hydrate to synthesized acide hydrazide [III] and the later compound reaction with substituted acetophenone[IV]n to synthesized substituted acetophenone hydrazones[V-XI]. In addition synthesized4-formylpyrazole derivatives [XIIXVIII] via cyclisation substituted acetophenone hydrazones [V-XI] with Vilsmeier-Haack reagent DMF/POCl3. The compounds characterized by melting points, FTIR, 1HNMR and mass spectroscopy. The mesomorphic behavior studied by using polarized optical microscopy and
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The nonprescription and huge used pharmaceuticals ibuprofen and diclofenac sodium will be focused in this study. New adsorbent developed using cheap inorganic clay material (bentonite) and organic polymer polyureaformaldehyde (PUF), the combination of these two materials gave the surface more roughness with wide active site distribution. Batch adsorption experiment performed to each pharmaceutical individually to determine the optimum separat
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