Synthesis and Biological Activity of Some New 1,3,4-Oxadiazoles Derived from Carboxylic Acids
(5)
(4)
Publication Date
Sun Jan 01 2023
Journal Name
Materials Today: Proceedings
(1)
(1)
Publication Date
Sat May 27 2017
Journal Name
Journal Of Pharmaceutical Sciences And Research
Synthesis, Preliminary Antimicrobial Evaluation
and Molecular Docking of new Schiff bases of
Ceftizoxime
Aldehydes
Antibacterial activity
Ceftizoxime sodium
Molecular docking
Schiff bases.
Schiff bases of Ceftizoxime sodium were synthesized in an attempt to improve the antimicrobial spectrum of Ceftizoxime. Aminothiazole ring of Ceftizoxime is linked directly through an imino group to different aromatic aldehydes reacted by nucleophilic addition using trimethylamine (TEA), as a catalyst and refluxed in methanol. The antimicrobial activity was evaluated for such Schiff bases using disc diffusion method. Molecular docking was conducted on certain penicillin-binding proteins (PBPs) and carboxypeptidases using 1- click docking software. Schiff bases of Ceftizoxime were prepared with reasonable yields and their chemical structures were confirmed by spectral analysis (FTIR, 1H-NMR) and elemental microanalysis (CHNS). The antibacter
... Show MorePublication Date
Sun Apr 20 2025
Journal Name
Ihjpas
Synthesis, Characterization, and Study of Liquid Crystals Properties of
New Five Heterocyclic Compounds
Heterocyclics
Isotropic
Liquid crystal
Mesomorphic
Thiazolo[4
3-b][1
3
4]
thiadiazol.
Heterocyclic compounds are employed in many applications, and numerous researchers have created liquid crystals by adding heterocyclic to the structures of these molecules. This work includes the synthesis and characterization of new compounds that contain 5H-thiazolo [4,3-b][1,3,4] thiadiazol united in multiple steps, starting with the synthesis of the aldehyde compound [I] by reaction chloro ethyl acetate with 4-hydroxybenzaldehyde in the presence of ethanol and potassium carbonate, followed by reactions with thiosemicarbazide, mercapto acetic acid in sulphuric acid to produce compound [II] then reflux compound [II] with hydrazine hydrate to product compound [III], after that reaction the later compound with nalkoxybenzaldehyde [IV]n and
... Show MorePublication Date
Wed Jul 09 2025
Journal Name
Applied Organometallic Chemistry
Evaluation of Anticancer and Antioxidant Activity of New Metal Ions Fe(III), Co(II), Ru(III), and Rh(III) Complexes With New Azo Dye
anticancer | antioxidant | MCF-7 | metal ions complexes | thermal analysis
The azo dye (LH) was used to synthesize a series of complexes with Fe(III), Co(II), Ru(III), and Rh(III) metal ions. The ligand (LH) was synthesized by the condensation reaction between tryptamine and 2-hydroxyquinoline. Due to the presence of effective donor atoms (-N=N- azo and OH hydroxyl groups), the ligand was subsequently refluxed with various metal ions, leading to the formation of nonelectrolytic [M:L] (1:2). These compounds were characterized using 1H and 13C-NMR, FT-IR, UV–Vis, mass spectrometry, TGA, DSC, and C.H.N. analysis, along with conductivity, magnetic susceptibility, and metal and chlorine content measurements. The results indicated that the ligand acts as a bidentate, with the complexes adopting an octahedral geometry.
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(2)
Publication Date
Mon Jun 01 2020
Journal Name
Life Sciences
(4)
(5)
Publication Date
Tue Oct 01 2024
Journal Name
Results In Chemistry
(3)
Publication Date
Mon Nov 01 2021
Journal Name
Journal Of Physics: Conference Series
Synthesis of Composite from Bacterial Cellulose and Gold Nanoparticles
Abstract<p>A process of bacterial cellulose gold nanocomposite has been investigated based on experimental work and cited literature. A literature review on the production process is carried out in this study. Bacterial cellulose is a high crystalline fabric material generally used in biomedical applications. A Nanocomposite was made by synthesis from gold and bacterial cellulose. The experimental work includes growing, and isolating bacterial cellulose, preparation of gold Nanoparticles and preparation of Nano composite. Nanoparticle’s formation and adsorption on the cellulose tissue have been observed visually, where a colour change was observed. The predicted particle size for the gold nano</p>
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(3)
(1)
Publication Date
Sun Jun 01 2014
Journal Name
Baghdad Science Journal
Preparation and Identification of some new Pyrazolopyrin derivatives and their Polymerizations study
Synthesis
Fused Pyrazoles
1-(3
6-dimethyl-4-oxo-1
4-dihydro-5H-pyrazolo [4
3-C] pyridin-5-yl)-1H-pyrrole-2
5-Dione S1
1-[2-(3
6-dimethyl-4-oxo-1-phenyl-1
4-dihydro-5H-pyrazolo[4
3-C]pyridin-5-yl)ethyl]-1H-pyrrole-2
5-DioneS2 and 1-(3
6-dimethyl-4-oxo-1-phenyl-1
4-dihydro-5H-pyrazolo[4
3-C]pyridin-5-yl)-1H-pyrrole-2
5-Dione S3
reactivity ratios
copolymer composition
Mean Sequence lengths.
Preparation and Identification of some new Pyrazolopyrin derivatives and their Polymerizations study
Publication Date
Sat Dec 01 2018
Journal Name
Engineering And Technology Journal
Publication Date
Thu Jan 01 2015
Journal Name
International Journal Of Science And Research