The research aims to identify the effect of the inquiry wheel model on the achievement of chemistry among second-grade middle school students in public daytime middle and secondary schools. Umm Al-Qura intermediate school for girls was chosen intentionally, where students were assigned as a research sample affiliated with the Third Rusafa Directorate for the academic year (2024-2025). Two classes of the secondgrade classes were randomly selected, one of which was the first group that studied according to the inquiry wheel model, and the other was the second group that studied according to the traditional method. Equivalence was carried out between the two research groups considering chronological age in months, previous achievement in chemistry, previous information test, and the Raven intelligence test. The research concluded that the two groups were equivalent. As for the research tool, the researchers developed an achievement test consisting of 40 items, 38 objective items, and 2 essay items. The results of research showed that there are statistically significant differences at the level of 0.05 between the average scores of the experimental group, who studied according to the inquiry wheel model, and the average scores of the control group, who studied according to the traditional method, in favor of the experimental group. In light of that, a set of recommendations and conclusions was developed.